Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | CANCER_UNDIFFERENTIATED_META_UP |
| Enrichment Score (ES) | -0.63049746 |
| Normalized Enrichment Score (NES) | -1.9157455 |
| Nominal p-value | 0.0020120724 |
| FDR q-value | 0.021430586 |
| FWER p-Value | 0.397 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CXCL9 | CXCL9 Entrez, Source | chemokine (C-X-C motif) ligand 9 | 1860 | 0.128 | -0.1172 | No |
| 2 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 2379 | 0.107 | -0.1372 | No |
| 3 | SLC16A1 | SLC16A1 Entrez, Source | solute carrier family 16, member 1 (monocarboxylic acid transporter 1) | 2935 | 0.087 | -0.1636 | No |
| 4 | ADRM1 | ADRM1 Entrez, Source | adhesion regulating molecule 1 | 3505 | 0.071 | -0.1938 | No |
| 5 | KPNA2 | KPNA2 Entrez, Source | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 3717 | 0.066 | -0.1980 | No |
| 6 | NUDT1 | NUDT1 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | 4723 | 0.043 | -0.2659 | No |
| 7 | GARS | GARS Entrez, Source | glycyl-tRNA synthetase | 5484 | 0.028 | -0.3181 | No |
| 8 | EIF2S2 | EIF2S2 Entrez, Source | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 6438 | 0.009 | -0.3881 | No |
| 9 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 6709 | 0.004 | -0.4077 | No |
| 10 | PSMB7 | PSMB7 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 7 | 6920 | -0.000 | -0.4235 | No |
| 11 | SSBP1 | SSBP1 Entrez, Source | single-stranded DNA binding protein 1 | 7057 | -0.003 | -0.4331 | No |
| 12 | NME1 | NME1 Entrez, Source | non-metastatic cells 1, protein (NM23A) expressed in | 8399 | -0.032 | -0.5282 | No |
| 13 | CTSL | CTSL Entrez, Source | cathepsin L | 8440 | -0.033 | -0.5254 | No |
| 14 | GAS6 | GAS6 Entrez, Source | growth arrest-specific 6 | 8485 | -0.034 | -0.5227 | No |
| 15 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 8540 | -0.035 | -0.5205 | No |
| 16 | SLC7A5 | SLC7A5 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 8548 | -0.036 | -0.5147 | No |
| 17 | GCLM | GCLM Entrez, Source | glutamate-cysteine ligase, modifier subunit | 8939 | -0.045 | -0.5362 | No |
| 18 | CCT6A | CCT6A Entrez, Source | chaperonin containing TCP1, subunit 6A (zeta 1) | 9113 | -0.049 | -0.5406 | No |
| 19 | TMSB10 | TMSB10 Entrez, Source | thymosin, beta 10 | 9124 | -0.049 | -0.5326 | No |
| 20 | CDKN3 | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 9252 | -0.053 | -0.5328 | No |
| 21 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 9272 | -0.054 | -0.5248 | No |
| 22 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 10651 | -0.097 | -0.6112 | Yes |
| 23 | FOXM1 | FOXM1 Entrez, Source | forkhead box M1 | 10847 | -0.105 | -0.6074 | Yes |
| 24 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 11099 | -0.117 | -0.6057 | Yes |
| 25 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 11117 | -0.118 | -0.5862 | Yes |
| 26 | PRDX4 | PRDX4 Entrez, Source | peroxiredoxin 4 | 11707 | -0.150 | -0.6041 | Yes |
| 27 | KIF2C | KIF2C Entrez, Source | kinesin family member 2C | 11889 | -0.164 | -0.5888 | Yes |
| 28 | TAP1 | TAP1 Entrez, Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 12194 | -0.191 | -0.5780 | Yes |
| 29 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 12504 | -0.229 | -0.5608 | Yes |
| 30 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 12818 | -0.293 | -0.5327 | Yes |
| 31 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 12822 | -0.294 | -0.4811 | Yes |
| 32 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12824 | -0.294 | -0.4294 | Yes |
| 33 | TUBB | TUBB Entrez, Source | tubulin, beta | 12961 | -0.344 | -0.3789 | Yes |
| 34 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 12986 | -0.357 | -0.3178 | Yes |
| 35 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13128 | -0.448 | -0.2495 | Yes |
| 36 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 13247 | -0.677 | -0.1390 | Yes |
| 37 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13289 | -0.828 | 0.0040 | Yes |
