Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | CARBON_CARBON_LYASE_ACTIVITY |
| Enrichment Score (ES) | 0.8173289 |
| Normalized Enrichment Score (NES) | 2.1639018 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.1256397E-4 |
| FWER p-Value | 0.0060 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 167 | 0.505 | 0.1137 | Yes |
| 2 | HACL1 | HACL1 Entrez, Source | 2-hydroxyacyl-CoA lyase 1 | 177 | 0.496 | 0.2370 | Yes |
| 3 | ACMSD | ACMSD Entrez, Source | aminocarboxymuconate semialdehyde decarboxylase | 269 | 0.420 | 0.3350 | Yes |
| 4 | BCKDHB | BCKDHB Entrez, Source | branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease) | 271 | 0.419 | 0.4397 | Yes |
| 5 | MVD | MVD Entrez, Source | mevalonate (diphospho) decarboxylase | 328 | 0.380 | 0.5303 | Yes |
| 6 | BCKDHA | BCKDHA Entrez, Source | branched chain keto acid dehydrogenase E1, alpha polypeptide | 389 | 0.344 | 0.6118 | Yes |
| 7 | MLYCD | MLYCD Entrez, Source | malonyl-CoA decarboxylase | 584 | 0.271 | 0.6650 | Yes |
| 8 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 666 | 0.249 | 0.7211 | Yes |
| 9 | ALDOC | ALDOC Entrez, Source | aldolase C, fructose-bisphosphate | 1047 | 0.187 | 0.7394 | Yes |
| 10 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 1205 | 0.170 | 0.7701 | Yes |
| 11 | HDC | HDC Entrez, Source | histidine decarboxylase | 1256 | 0.167 | 0.8081 | Yes |
| 12 | AMD1 | AMD1 Entrez, Source | adenosylmethionine decarboxylase 1 | 1608 | 0.143 | 0.8173 | Yes |
| 13 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 3130 | 0.081 | 0.7233 | No |
| 14 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 5183 | 0.034 | 0.5779 | No |
| 15 | UMPS | UMPS Entrez, Source | uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) | 7149 | -0.005 | 0.4318 | No |
| 16 | GGCX | GGCX Entrez, Source | gamma-glutamyl carboxylase | 7862 | -0.020 | 0.3833 | No |
| 17 | UROD | UROD Entrez, Source | uroporphyrinogen decarboxylase | 8955 | -0.045 | 0.3126 | No |
| 18 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 9745 | -0.066 | 0.2699 | No |
