Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | CELLCYCLEPATHWAY |
| Enrichment Score (ES) | -0.6708355 |
| Normalized Enrichment Score (NES) | -1.7754551 |
| Nominal p-value | 0.0059288535 |
| FDR q-value | 0.053663876 |
| FWER p-Value | 0.968 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 2067 | 0.119 | -0.1170 | No |
| 2 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 2307 | 0.110 | -0.0996 | No |
| 3 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 3808 | 0.064 | -0.1917 | No |
| 4 | CCNE1 | CCNE1 Entrez, Source | cyclin E1 | 4056 | 0.058 | -0.1915 | No |
| 5 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4801 | 0.042 | -0.2339 | No |
| 6 | CCNA1 | CCNA1 Entrez, Source | cyclin A1 | 5345 | 0.031 | -0.2646 | No |
| 7 | CCNH | CCNH Entrez, Source | cyclin H | 7280 | -0.008 | -0.4072 | No |
| 8 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 7589 | -0.014 | -0.4257 | No |
| 9 | CCND3 | CCND3 Entrez, Source | cyclin D3 | 7859 | -0.020 | -0.4395 | No |
| 10 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 8322 | -0.030 | -0.4644 | No |
| 11 | CDKN2D | CDKN2D Entrez, Source | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 9788 | -0.068 | -0.5526 | No |
| 12 | CDK7 | CDK7 Entrez, Source | cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) | 9912 | -0.072 | -0.5387 | No |
| 13 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 11673 | -0.148 | -0.6232 | Yes |
| 14 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 12163 | -0.188 | -0.5995 | Yes |
| 15 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 12251 | -0.199 | -0.5422 | Yes |
| 16 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 12794 | -0.284 | -0.4914 | Yes |
| 17 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 12986 | -0.357 | -0.3910 | Yes |
| 18 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 13016 | -0.374 | -0.2728 | Yes |
| 19 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 13099 | -0.425 | -0.1425 | Yes |
| 20 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13162 | -0.500 | 0.0135 | Yes |
