Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | CELL_CYCLE |
| Enrichment Score (ES) | -0.7017938 |
| Normalized Enrichment Score (NES) | -2.1698728 |
| Nominal p-value | 0.0 |
| FDR q-value | 8.9846196E-4 |
| FWER p-Value | 0.0050 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 2067 | 0.119 | -0.1411 | No |
| 2 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 2307 | 0.110 | -0.1457 | No |
| 3 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 3808 | 0.064 | -0.2508 | No |
| 4 | CCNE1 | CCNE1 Entrez, Source | cyclin E1 | 4056 | 0.058 | -0.2623 | No |
| 5 | HDAC5 | HDAC5 Entrez, Source | histone deacetylase 5 | 4333 | 0.052 | -0.2768 | No |
| 6 | MAD2L2 | MAD2L2 Entrez, Source | MAD2 mitotic arrest deficient-like 2 (yeast) | 4562 | 0.047 | -0.2882 | No |
| 7 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4801 | 0.042 | -0.3010 | No |
| 8 | ORC2L | ORC2L Entrez, Source | origin recognition complex, subunit 2-like (yeast) | 5273 | 0.032 | -0.3325 | No |
| 9 | CCNA1 | CCNA1 Entrez, Source | cyclin A1 | 5345 | 0.031 | -0.3341 | No |
| 10 | HDAC3 | HDAC3 Entrez, Source | histone deacetylase 3 | 6040 | 0.017 | -0.3842 | No |
| 11 | ORC4L | ORC4L Entrez, Source | origin recognition complex, subunit 4-like (yeast) | 6443 | 0.009 | -0.4133 | No |
| 12 | CCNH | CCNH Entrez, Source | cyclin H | 7280 | -0.008 | -0.4752 | No |
| 13 | CCND3 | CCND3 Entrez, Source | cyclin D3 | 7859 | -0.020 | -0.5163 | No |
| 14 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 8707 | -0.039 | -0.5752 | No |
| 15 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 8782 | -0.040 | -0.5759 | No |
| 16 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 9083 | -0.048 | -0.5926 | No |
| 17 | BUB1B | BUB1B Entrez, Source | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 10391 | -0.088 | -0.6803 | No |
| 18 | YWHAG | YWHAG Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 10619 | -0.096 | -0.6857 | No |
| 19 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 10651 | -0.097 | -0.6763 | No |
| 20 | BUB3 | BUB3 Entrez, Source | BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) | 10991 | -0.111 | -0.6883 | Yes |
| 21 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 11099 | -0.117 | -0.6823 | Yes |
| 22 | CDC25B | CDC25B Entrez, Source | cell division cycle 25B | 11352 | -0.129 | -0.6856 | Yes |
| 23 | E2F5 | E2F5 Entrez, Source | E2F transcription factor 5, p130-binding | 11463 | -0.135 | -0.6775 | Yes |
| 24 | PTTG1 | PTTG1 Entrez, Source | pituitary tumor-transforming 1 | 11624 | -0.145 | -0.6720 | Yes |
| 25 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 11673 | -0.148 | -0.6577 | Yes |
| 26 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 11690 | -0.149 | -0.6408 | Yes |
| 27 | CHEK2 | CHEK2 Entrez, Source | CHK2 checkpoint homolog (S. pombe) | 12031 | -0.176 | -0.6451 | Yes |
| 28 | HDAC7A | HDAC7A Entrez, Source | histone deacetylase 7A | 12032 | -0.176 | -0.6239 | Yes |
| 29 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 12163 | -0.188 | -0.6109 | Yes |
| 30 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 12251 | -0.199 | -0.5934 | Yes |
| 31 | ORC3L | ORC3L Entrez, Source | origin recognition complex, subunit 3-like (yeast) | 12302 | -0.205 | -0.5723 | Yes |
| 32 | HDAC6 | HDAC6 Entrez, Source | histone deacetylase 6 | 12329 | -0.208 | -0.5491 | Yes |
| 33 | ORC6L | ORC6L Entrez, Source | origin recognition complex, subunit 6 like (yeast) | 12525 | -0.232 | -0.5357 | Yes |
| 34 | HDAC2 | HDAC2 Entrez, Source | histone deacetylase 2 | 12630 | -0.250 | -0.5132 | Yes |
| 35 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 12794 | -0.284 | -0.4911 | Yes |
| 36 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 12821 | -0.294 | -0.4575 | Yes |
| 37 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12897 | -0.319 | -0.4244 | Yes |
| 38 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 12954 | -0.340 | -0.3875 | Yes |
| 39 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 12986 | -0.357 | -0.3466 | Yes |
| 40 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 13016 | -0.374 | -0.3035 | Yes |
| 41 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13028 | -0.381 | -0.2582 | Yes |
| 42 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 13047 | -0.395 | -0.2118 | Yes |
| 43 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 13099 | -0.425 | -0.1642 | Yes |
| 44 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 13247 | -0.677 | -0.0932 | Yes |
| 45 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13289 | -0.828 | 0.0040 | Yes |
