Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | CELL_CYCLE_CHECKPOINT |
| Enrichment Score (ES) | -0.6335361 |
| Normalized Enrichment Score (NES) | -1.620657 |
| Nominal p-value | 0.021400778 |
| FDR q-value | 0.10736355 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MSH3 | MSH3 Entrez, Source | mutS homolog 3 (E. coli) | 444 | 0.323 | 0.0722 | No |
| 2 | RAD17 | RAD17 Entrez, Source | RAD17 homolog (S. pombe) | 2601 | 0.099 | -0.0572 | No |
| 3 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 4925 | 0.039 | -0.2186 | No |
| 4 | LCMT2 | LCMT2 Entrez, Source | leucine carboxyl methyltransferase 2 | 8973 | -0.045 | -0.5075 | No |
| 5 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 9083 | -0.048 | -0.5000 | No |
| 6 | RAD50 | RAD50 Entrez, Source | RAD50 homolog (S. cerevisiae) | 10151 | -0.080 | -0.5540 | No |
| 7 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 11212 | -0.122 | -0.5937 | Yes |
| 8 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 11523 | -0.139 | -0.5717 | Yes |
| 9 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 11589 | -0.143 | -0.5300 | Yes |
| 10 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 11690 | -0.149 | -0.4888 | Yes |
| 11 | CHEK2 | CHEK2 Entrez, Source | CHK2 checkpoint homolog (S. pombe) | 12031 | -0.176 | -0.4570 | Yes |
| 12 | MRE11A | MRE11A Entrez, Source | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 12243 | -0.198 | -0.4082 | Yes |
| 13 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 12821 | -0.294 | -0.3557 | Yes |
| 14 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13028 | -0.381 | -0.2469 | Yes |
| 15 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13289 | -0.828 | 0.0040 | Yes |
