Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_single_gel_8d.class.cls
#double_gel_8d_versus_single_gel_8d_repos
Phenotypeclass.cls#double_gel_8d_versus_single_gel_8d_repos
Upregulated in classsingle_gel_8d
GeneSetCELL_CYCLE_GO_0007049
Enrichment Score (ES)-0.48063856
Normalized Enrichment Score (NES)-1.8628359
Nominal p-value0.0
FDR q-value0.029655136
FWER p-Value0.655
Table: GSEA Results Summary



Fig 1: Enrichment plot: CELL_CYCLE_GO_0007049   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1BMP2BMP2
Entrez,  Source
bone morphogenetic protein 23700.355-0.0108No
2MDM4MDM4
Entrez,  Source
Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse)6050.265-0.0156No
3BMP7BMP7
Entrez,  Source
bone morphogenetic protein 7 (osteogenic protein 1)6350.257-0.0053No
4TGFATGFA
Entrez,  Source
transforming growth factor, alpha7400.230-0.0019No
5PTPRCPTPRC
Entrez,  Source
protein tyrosine phosphatase, receptor type, C12380.168-0.0315No
6EGFL6EGFL6
Entrez,  Source
EGF-like-domain, multiple 614860.151-0.0429No
7CDK5R1CDK5R1
Entrez,  Source
cyclin-dependent kinase 5, regulatory subunit 1 (p35)16300.141-0.0468No
8EGFEGF
Entrez,  Source
epidermal growth factor (beta-urogastrone)16950.137-0.0450No
9SPDYASPDYA
Entrez,  Source
speedy homolog A (Drosophila)19940.122-0.0616No
10ZWINTZWINT
Entrez,  Source
ZW10 interactor20550.119-0.0604No
11CDK6CDK6
Entrez,  Source
cyclin-dependent kinase 620670.119-0.0554No
12BMP4BMP4
Entrez,  Source
bone morphogenetic protein 421160.117-0.0534No
13RB1RB1
Entrez,  Source
retinoblastoma 1 (including osteosarcoma)23070.110-0.0624No
14ASNSASNS
Entrez,  Source
asparagine synthetase24240.106-0.0661No
15RAD17RAD17
Entrez,  Source
RAD17 homolog (S. pombe)26010.099-0.0746No
16RUNX3RUNX3
Entrez,  Source
runt-related transcription factor 327070.095-0.0779No
17HPGDHPGD
Entrez,  Source
hydroxyprostaglandin dehydrogenase 15-(NAD)28320.090-0.0829No
18PPP5CPPP5C
Entrez,  Source
protein phosphatase 5, catalytic subunit29450.087-0.0872No
19TBRG4TBRG4
Entrez,  Source
transforming growth factor beta regulator 431010.081-0.0950No
20SMC1ASMC1A
Entrez,  Source
structural maintenance of chromosomes 1A31090.081-0.0915No
21SUGT1SUGT1
Entrez,  Source
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)31980.079-0.0944No
22USH1CUSH1C
Entrez,  Source
Usher syndrome 1C (autosomal recessive, severe)33030.076-0.0986No
23SYCP1SYCP1
Entrez,  Source
synaptonemal complex protein 133230.075-0.0963No
24CDK5RAP1CDK5RAP1
Entrez,  Source
CDK5 regulatory subunit associated protein 135680.069-0.1114No
25EREGEREG
Entrez,  Source
epiregulin36250.068-0.1124No
26KPNA2KPNA2
Entrez,  Source
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)37170.066-0.1161No
27MYCMYC
Entrez,  Source
v-myc myelocytomatosis viral oncogene homolog (avian)38050.064-0.1195No
28CDK2CDK2
Entrez,  Source
cyclin-dependent kinase 238080.064-0.1166No
29AIF1AIF1
Entrez,  Source
allograft inflammatory factor 138390.063-0.1158No
30CENTD2CENTD2
Entrez,  Source
centaurin, delta 238600.063-0.1142No
31RHOBRHOB
Entrez,  Source
ras homolog gene family, member B38720.063-0.1120No
32TBX3TBX3
Entrez,  Source
T-box 3 (ulnar mammary syndrome)41430.056-0.1298No
33INHAINHA
Entrez,  Source
inhibin, alpha41830.055-0.1300No
34PCAFPCAF
Entrez,  Source
p300/CBP-associated factor42090.055-0.1292No
35TTNTTN
Entrez,  Source
titin44010.050-0.1413No
36CDK5RAP3CDK5RAP3
Entrez,  Source
CDK5 regulatory subunit associated protein 344590.049-0.1432No
37MAD2L2MAD2L2
Entrez,  Source
MAD2 mitotic arrest deficient-like 2 (yeast)45620.047-0.1486No
38CDC25ACDC25A
Entrez,  Source
cell division cycle 25A48010.042-0.1646No
39GAS7GAS7
Entrez,  Source
growth arrest-specific 750730.036-0.1834No
40STAG3STAG3
Entrez,  Source
stromal antigen 351670.035-0.1888No
41CCNA1CCNA1
Entrez,  Source
cyclin A153450.031-0.2007No
42NEK6NEK6
Entrez,  Source
NIMA (never in mitosis gene a)-related kinase 653930.030-0.2028No
43GFI1GFI1
Entrez,  Source
growth factor independent 156400.025-0.2202No
44DUSP13DUSP13
Entrez,  Source
dual specificity phosphatase 1357020.024-0.2237No
45BTG4BTG4
Entrez,  Source
B-cell translocation gene 457690.022-0.2276No
46ZBTB17ZBTB17
Entrez,  Source
zinc finger and BTB domain containing 1758590.021-0.2333No
47CDC2L5CDC2L5
Entrez,  Source
cell division cycle 2-like 5 (cholinesterase-related cell division controller)59250.020-0.2373No
48UHMK1UHMK1
Entrez,  Source
U2AF homology motif (UHM) kinase 166510.005-0.2920No
49PLAGL1PLAGL1
Entrez,  Source
pleiomorphic adenoma gene-like 166680.005-0.2930No
50CETN3CETN3
Entrez,  Source
centrin, EF-hand protein, 3 (CDC31 homolog, yeast)68560.001-0.3071No
51SNF1LKSNF1LK
Entrez,  Source
SNF1-like kinase6978-0.002-0.3162No
52PPM1GPPM1G
Entrez,  Source
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform7035-0.003-0.3203No
53SERTAD1SERTAD1
Entrez,  Source
SERTA domain containing 17125-0.005-0.3269No
54MFN2MFN2
Entrez,  Source
mitofusin 27196-0.006-0.3319No
55INHBAINHBA
Entrez,  Source
inhibin, beta A (activin A, activin AB alpha polypeptide)7375-0.010-0.3449No
56CDKN2BCDKN2B
Entrez,  Source
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)7589-0.014-0.3604No
57GTPBP4GTPBP4
Entrez,  Source
GTP binding protein 47656-0.016-0.3646No
58MAP2K6MAP2K6
Entrez,  Source
mitogen-activated protein kinase kinase 67666-0.016-0.3645No
59KATNA1KATNA1
Entrez,  Source
katanin p60 (ATPase-containing) subunit A 17746-0.018-0.3697No
60CCND3CCND3
Entrez,  Source
cyclin D37859-0.020-0.3772No
61DLG1DLG1
Entrez,  Source
discs, large homolog 1 (Drosophila)8008-0.024-0.3873No
62NPM1NPM1
Entrez,  Source
nucleophosmin (nucleolar phosphoprotein B23, numatrin)8204-0.028-0.4007No
63CDKN2CCDKN2C
Entrez,  Source
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)8322-0.030-0.4081No
64MAP3K11MAP3K11
Entrez,  Source
mitogen-activated protein kinase kinase kinase 118842-0.042-0.4454No
65PA2G4PA2G4
Entrez,  Source
proliferation-associated 2G4, 38kDa8877-0.043-0.4459No
66PPP6CPPP6C
Entrez,  Source
protein phosphatase 6, catalytic subunit8915-0.044-0.4466No
67NASPNASP
Entrez,  Source
nuclear autoantigenic sperm protein (histone-binding)8949-0.045-0.4469No
68GADD45AGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha9083-0.048-0.4546No
69NOLC1NOLC1
Entrez,  Source
nucleolar and coiled-body phosphoprotein 19128-0.050-0.4555No
70NPM2NPM2
Entrez,  Source
nucleophosmin/nucleoplasmin, 29187-0.051-0.4575No
71GPS1GPS1
Entrez,  Source
G protein pathway suppressor 19208-0.051-0.4565No
72CUL5CUL5
Entrez,  Source
cullin 59220-0.052-0.4548No
73CDKN3CDKN3
Entrez,  Source
cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase)9252-0.053-0.4546No
74PTENPTEN
Entrez,  Source
phosphatase and tensin homolog (mutated in multiple advanced cancers 1)9345-0.056-0.4588No
75RANRAN
Entrez,  Source
RAN, member RAS oncogene family9534-0.061-0.4701No
76GSPT1GSPT1
Entrez,  Source
G1 to S phase transition 19560-0.061-0.4690No
77TARDBPTARDBP
Entrez,  Source
TAR DNA binding protein9617-0.063-0.4702No
78ZW10ZW10
Entrez,  Source
ZW10, kinetochore associated, homolog (Drosophila)9627-0.063-0.4678No
79CDKN2DCDKN2D
Entrez,  Source
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)9788-0.068-0.4766No
80ANAPC4ANAPC4
Entrez,  Source
anaphase promoting complex subunit 49814-0.069-0.4752No
81TUBG1TUBG1
Entrez,  Source
tubulin, gamma 19827-0.069-0.4727No
82PPP1R9BPPP1R9B
Entrez,  Source
protein phosphatase 1, regulatory subunit 9B, spinophilin9861-0.070-0.4718No
83STRN3STRN3
Entrez,  Source
striatin, calmodulin binding protein 39894-0.071-0.4707No
84CDK7CDK7
Entrez,  Source
cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)9912-0.072-0.4685No
85BRCA2BRCA2
Entrez,  Source
breast cancer 2, early onset10026-0.075-0.4734No
86NBNNBN
Entrez,  Source
nibrin10122-0.079-0.4768Yes
87ERCC3ERCC3
Entrez,  Source
excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)10127-0.079-0.4732Yes
88RAD50RAD50
Entrez,  Source
RAD50 homolog (S. cerevisiae)10151-0.080-0.4711Yes
89UBBUBB
Entrez,  Source
ubiquitin B10179-0.081-0.4692Yes
90APBB1APBB1
Entrez,  Source
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)10220-0.082-0.4683Yes
91PLK1PLK1
Entrez,  Source
polo-like kinase 1 (Drosophila)10276-0.084-0.4683Yes
92APCAPC
Entrez,  Source
adenomatosis polyposis coli10296-0.085-0.4657Yes
93DCTN2DCTN2
Entrez,  Source
dynactin 2 (p50)10303-0.085-0.4620Yes
94LIG3LIG3
Entrez,  Source
ligase III, DNA, ATP-dependent10312-0.085-0.4585Yes
95BUB1BBUB1B
Entrez,  Source
BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)10391-0.088-0.4601Yes
96SC65SC65
Entrez,  Source
-10443-0.090-0.4596Yes
97CETN1CETN1
Entrez,  Source
centrin, EF-hand protein, 110599-0.095-0.4667Yes
98RASSF1RASSF1
Entrez,  Source
Ras association (RalGDS/AF-6) domain family 110613-0.096-0.4630Yes
99EIF4G2EIF4G2
Entrez,  Source
eukaryotic translation initiation factor 4 gamma, 210707-0.099-0.4653Yes
100CHFRCHFR
Entrez,  Source
checkpoint with forkhead and ring finger domains10712-0.099-0.4608Yes
101PAFAH1B1PAFAH1B1
Entrez,  Source
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa10819-0.104-0.4637Yes
102MADDMADD
Entrez,  Source
MAP-kinase activating death domain10825-0.104-0.4590Yes
103MNAT1MNAT1
Entrez,  Source
menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)10832-0.104-0.4544Yes
104CITED2CITED2
Entrez,  Source
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 211087-0.116-0.4680Yes
105CDC20CDC20
Entrez,  Source
CDC20 cell division cycle 20 homolog (S. cerevisiae)11099-0.117-0.4632Yes
106BIRC5BIRC5
Entrez,  Source
baculoviral IAP repeat-containing 5 (survivin)11117-0.118-0.4587Yes
107AKAP8AKAP8
Entrez,  Source
A kinase (PRKA) anchor protein 811248-0.124-0.4626Yes
108CDC25BCDC25B
Entrez,  Source
cell division cycle 25B11352-0.129-0.4641Yes
109CDC16CDC16
Entrez,  Source
CDC16 cell division cycle 16 homolog (S. cerevisiae)11467-0.135-0.4661Yes
110CDK10CDK10
Entrez,  Source
cyclin-dependent kinase (CDC2-like) 1011493-0.137-0.4614Yes
111SMAD3SMAD3
Entrez,  Source
SMAD, mothers against DPP homolog 3 (Drosophila)11527-0.139-0.4571Yes
112AHRAHR
Entrez,  Source
aryl hydrocarbon receptor11529-0.139-0.4504Yes
113NDE1NDE1
Entrez,  Source
nudE nuclear distribution gene E homolog 1 (A. nidulans)11603-0.144-0.4489Yes
114MYH10MYH10
Entrez,  Source
myosin, heavy chain 10, non-muscle11608-0.144-0.4422Yes
115CITCIT
Entrez,  Source
citron (rho-interacting, serine/threonine kinase 21)11639-0.146-0.4374Yes
116CDC27CDC27
Entrez,  Source
cell division cycle 2711658-0.148-0.4315Yes
117BTG3BTG3
Entrez,  Source
BTG family, member 311661-0.148-0.4245Yes
118POLD1POLD1
Entrez,  Source
polymerase (DNA directed), delta 1, catalytic subunit 125kDa11672-0.148-0.4180Yes
119E2F1E2F1
Entrez,  Source
E2F transcription factor 111673-0.148-0.4108Yes
120TP53TP53
Entrez,  Source
tumor protein p53 (Li-Fraumeni syndrome)11690-0.149-0.4048Yes
121TBRG1TBRG1
Entrez,  Source
transforming growth factor beta regulator 111701-0.150-0.3982Yes
122CCNG1CCNG1
Entrez,  Source
cyclin G111744-0.152-0.3940Yes
123CD28CD28
Entrez,  Source
CD28 molecule11745-0.152-0.3866Yes
124DDB1DDB1
Entrez,  Source
damage-specific DNA binding protein 1, 127kDa11887-0.163-0.3893Yes
125KIF2CKIF2C
Entrez,  Source
kinesin family member 2C11889-0.164-0.3814Yes
126SMC4SMC4
Entrez,  Source
structural maintenance of chromosomes 411916-0.167-0.3753Yes
127ACVR1ACVR1
Entrez,  Source
activin A receptor, type I11998-0.173-0.3730Yes
128SMC3SMC3
Entrez,  Source
structural maintenance of chromosomes 312021-0.175-0.3662Yes
129CHEK2CHEK2
Entrez,  Source
CHK2 checkpoint homolog (S. pombe)12031-0.176-0.3583Yes
130KHDRBS1KHDRBS1
Entrez,  Source
KH domain containing, RNA binding, signal transduction associated 112056-0.178-0.3514Yes
131HSPA2HSPA2
Entrez,  Source
heat shock 70kDa protein 212146-0.186-0.3491Yes
132CDKN1ACDKN1A
Entrez,  Source
cyclin-dependent kinase inhibitor 1A (p21, Cip1)12163-0.188-0.3412Yes
133CDC23CDC23
Entrez,  Source
CDC23 (cell division cycle 23, yeast, homolog)12182-0.190-0.3333Yes
134MAPK12MAPK12
Entrez,  Source
mitogen-activated protein kinase 1212219-0.194-0.3266Yes
135MRE11AMRE11A
Entrez,  Source
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)12243-0.198-0.3187Yes
136CDKN1BCDKN1B
Entrez,  Source
cyclin-dependent kinase inhibitor 1B (p27, Kip1)12251-0.199-0.3095Yes
137ANAPC2ANAPC2
Entrez,  Source
anaphase promoting complex subunit 212258-0.199-0.3003Yes
138CDC37CDC37
Entrez,  Source
CDC37 cell division cycle 37 homolog (S. cerevisiae)12294-0.204-0.2930Yes
139SH3BP4SH3BP4
Entrez,  Source
SH3-domain binding protein 412316-0.206-0.2845Yes
140ING4ING4
Entrez,  Source
inhibitor of growth family, member 412380-0.212-0.2790Yes
141NUMA1NUMA1
Entrez,  Source
nuclear mitotic apparatus protein 112531-0.233-0.2790Yes
142AURKAAURKA
Entrez,  Source
aurora kinase A12548-0.235-0.2687Yes
143CKAP5CKAP5
Entrez,  Source
cytoskeleton associated protein 512613-0.247-0.2615Yes
144TIMELESSTIMELESS
Entrez,  Source
timeless homolog (Drosophila)12644-0.253-0.2515Yes
145SPHK1SPHK1
Entrez,  Source
sphingosine kinase 112700-0.264-0.2428Yes
146KIF22KIF22
Entrez,  Source
kinesin family member 2212713-0.267-0.2307Yes
147CDKN1CCDKN1C
Entrez,  Source
cyclin-dependent kinase inhibitor 1C (p57, Kip2)12725-0.270-0.2183Yes
148NOTCH2NOTCH2
Entrez,  Source
Notch homolog 2 (Drosophila)12734-0.272-0.2057Yes
149CDK4CDK4
Entrez,  Source
cyclin-dependent kinase 412794-0.284-0.1963Yes
150CHEK1CHEK1
Entrez,  Source
CHK1 checkpoint homolog (S. pombe)12821-0.294-0.1839Yes
151TGFB2TGFB2
Entrez,  Source
transforming growth factor, beta 212832-0.296-0.1703Yes
152CCND2CCND2
Entrez,  Source
cyclin D213016-0.374-0.1659Yes
153TGFB1TGFB1
Entrez,  Source
transforming growth factor, beta 1 (Camurati-Engelmann disease)13047-0.395-0.1489Yes
154CDKN2ACDKN2A
Entrez,  Source
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)13099-0.425-0.1321Yes
155CCND1CCND1
Entrez,  Source
cyclin D113162-0.500-0.1125Yes
156BCAT1BCAT1
Entrez,  Source
branched chain aminotransferase 1, cytosolic13167-0.505-0.0882Yes
157PAMPAM
Entrez,  Source
peptidylglycine alpha-amidating monooxygenase13208-0.576-0.0631Yes
158CCNA2CCNA2
Entrez,  Source
cyclin A213247-0.677-0.0330Yes
159STMN1STMN1
Entrez,  Source
stathmin 1/oncoprotein 1813288-0.8230.0041Yes
Table: GSEA details [plain text format]



Fig 2: CELL_CYCLE_GO_0007049   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: CELL_CYCLE_GO_0007049: Random ES distribution   
Gene set null distribution of ES for CELL_CYCLE_GO_0007049