Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | CELL_PROJECTION |
| Enrichment Score (ES) | -0.57755166 |
| Normalized Enrichment Score (NES) | -1.9138585 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.02052445 |
| FWER p-Value | 0.402 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PDPN | PDPN Entrez, Source | podoplanin | 1169 | 0.174 | -0.0649 | No |
| 2 | CDH13 | CDH13 Entrez, Source | cadherin 13, H-cadherin (heart) | 1338 | 0.162 | -0.0562 | No |
| 3 | CDK5R1 | CDK5R1 Entrez, Source | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 1630 | 0.141 | -0.0593 | No |
| 4 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 2067 | 0.119 | -0.0764 | No |
| 5 | SI | SI Entrez, Source | sucrase-isomaltase (alpha-glucosidase) | 2838 | 0.090 | -0.1225 | No |
| 6 | USH1C | USH1C Entrez, Source | Usher syndrome 1C (autosomal recessive, severe) | 3303 | 0.076 | -0.1473 | No |
| 7 | DFNB31 | DFNB31 Entrez, Source | deafness, autosomal recessive 31 | 3314 | 0.076 | -0.1380 | No |
| 8 | DNALI1 | DNALI1 Entrez, Source | dynein, axonemal, light intermediate chain 1 | 3330 | 0.075 | -0.1292 | No |
| 9 | GHSR | GHSR Entrez, Source | growth hormone secretagogue receptor | 3367 | 0.074 | -0.1220 | No |
| 10 | CACNA1A | CACNA1A Entrez, Source | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 4740 | 0.043 | -0.2196 | No |
| 11 | SLC22A12 | SLC22A12 Entrez, Source | solute carrier family 22 (organic anion/cation transporter), member 12 | 4810 | 0.042 | -0.2193 | No |
| 12 | MAPT | MAPT Entrez, Source | microtubule-associated protein tau | 4812 | 0.042 | -0.2138 | No |
| 13 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 5159 | 0.035 | -0.2353 | No |
| 14 | ABI3 | ABI3 Entrez, Source | ABI gene family, member 3 | 5293 | 0.032 | -0.2411 | No |
| 15 | EVL | EVL Entrez, Source | Enah/Vasp-like | 5460 | 0.029 | -0.2497 | No |
| 16 | TSC1 | TSC1 Entrez, Source | tuberous sclerosis 1 | 5506 | 0.028 | -0.2495 | No |
| 17 | AKAP4 | AKAP4 Entrez, Source | A kinase (PRKA) anchor protein 4 | 5529 | 0.027 | -0.2475 | No |
| 18 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 6561 | 0.007 | -0.3243 | No |
| 19 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 6686 | 0.004 | -0.3330 | No |
| 20 | FGD4 | FGD4 Entrez, Source | FYVE, RhoGEF and PH domain containing 4 | 6928 | -0.000 | -0.3511 | No |
| 21 | PIB5PA | PIB5PA Entrez, Source | phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A | 7047 | -0.003 | -0.3596 | No |
| 22 | ALS2 | ALS2 Entrez, Source | amyotrophic lateral sclerosis 2 (juvenile) | 7100 | -0.004 | -0.3630 | No |
| 23 | DTNBP1 | DTNBP1 Entrez, Source | dystrobrevin binding protein 1 | 7116 | -0.004 | -0.3635 | No |
| 24 | ARFIP2 | ARFIP2 Entrez, Source | ADP-ribosylation factor interacting protein 2 (arfaptin 2) | 7224 | -0.007 | -0.3707 | No |
| 25 | WASF2 | WASF2 Entrez, Source | WAS protein family, member 2 | 7261 | -0.008 | -0.3724 | No |
| 26 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 7461 | -0.012 | -0.3858 | No |
| 27 | NME2 | NME2 Entrez, Source | non-metastatic cells 2, protein (NM23B) expressed in | 7595 | -0.014 | -0.3939 | No |
| 28 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 7856 | -0.020 | -0.4109 | No |
| 29 | SYNPO | SYNPO Entrez, Source | synaptopodin | 8210 | -0.028 | -0.4338 | No |
| 30 | CDH23 | CDH23 Entrez, Source | cadherin-like 23 | 8219 | -0.028 | -0.4307 | No |
| 31 | ESPN | ESPN Entrez, Source | espin | 8501 | -0.034 | -0.4472 | No |
| 32 | FAP | FAP Entrez, Source | fibroblast activation protein, alpha | 8649 | -0.038 | -0.4533 | No |
| 33 | GHRL | GHRL Entrez, Source | ghrelin/obestatin preprohormone | 8739 | -0.040 | -0.4547 | No |
| 34 | PPT1 | PPT1 Entrez, Source | palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) | 9878 | -0.071 | -0.5311 | No |
| 35 | DBNL | DBNL Entrez, Source | drebrin-like | 10114 | -0.079 | -0.5383 | No |
| 36 | APBB1 | APBB1 Entrez, Source | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 10220 | -0.082 | -0.5354 | No |
| 37 | TBC1D10A | TBC1D10A Entrez, Source | TBC1 domain family, member 10A | 10325 | -0.086 | -0.5319 | No |
| 38 | CTTN | CTTN Entrez, Source | cortactin | 10911 | -0.107 | -0.5617 | No |
| 39 | BCAR1 | BCAR1 Entrez, Source | breast cancer anti-estrogen resistance 1 | 11123 | -0.118 | -0.5619 | Yes |
| 40 | TLN1 | TLN1 Entrez, Source | talin 1 | 11127 | -0.118 | -0.5464 | Yes |
| 41 | MYO5A | MYO5A Entrez, Source | myosin VA (heavy chain 12, myoxin) | 11192 | -0.121 | -0.5352 | Yes |
| 42 | NF1 | NF1 Entrez, Source | neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) | 11321 | -0.127 | -0.5279 | Yes |
| 43 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 11366 | -0.129 | -0.5141 | Yes |
| 44 | ITPR3 | ITPR3 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 3 | 11479 | -0.136 | -0.5045 | Yes |
| 45 | GAS8 | GAS8 Entrez, Source | growth arrest-specific 8 | 11506 | -0.138 | -0.4882 | Yes |
| 46 | NEFH | NEFH Entrez, Source | neurofilament, heavy polypeptide 200kDa | 11557 | -0.141 | -0.4733 | Yes |
| 47 | MYO1C | MYO1C Entrez, Source | myosin IC | 11628 | -0.145 | -0.4594 | Yes |
| 48 | S100B | S100B Entrez, Source | S100 calcium binding protein B | 11736 | -0.151 | -0.4474 | Yes |
| 49 | ABI1 | ABI1 Entrez, Source | abl-interactor 1 | 12095 | -0.181 | -0.4503 | Yes |
| 50 | FGD1 | FGD1 Entrez, Source | FYVE, RhoGEF and PH domain containing 1 (faciogenital dysplasia) | 12106 | -0.182 | -0.4269 | Yes |
| 51 | CDK5 | CDK5 Entrez, Source | cyclin-dependent kinase 5 | 12107 | -0.182 | -0.4027 | Yes |
| 52 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 12269 | -0.201 | -0.3883 | Yes |
| 53 | CLIC5 | CLIC5 Entrez, Source | chloride intracellular channel 5 | 12338 | -0.209 | -0.3657 | Yes |
| 54 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 12585 | -0.241 | -0.3522 | Yes |
| 55 | S100A11 | S100A11 Entrez, Source | S100 calcium binding protein A11 | 12634 | -0.251 | -0.3226 | Yes |
| 56 | CLIC4 | CLIC4 Entrez, Source | chloride intracellular channel 4 | 12732 | -0.272 | -0.2938 | Yes |
| 57 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 12832 | -0.296 | -0.2620 | Yes |
| 58 | S100A6 | S100A6 Entrez, Source | S100 calcium binding protein A6 | 12854 | -0.305 | -0.2232 | Yes |
| 59 | CLIC1 | CLIC1 Entrez, Source | chloride intracellular channel 1 | 13030 | -0.381 | -0.1859 | Yes |
| 60 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13226 | -0.619 | -0.1185 | Yes |
| 61 | NEFL | NEFL Entrez, Source | neurofilament, light polypeptide 68kDa | 13304 | -0.959 | 0.0029 | Yes |
