Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | CENTROSOME |
| Enrichment Score (ES) | -0.66174066 |
| Normalized Enrichment Score (NES) | -1.8384405 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.03638226 |
| FWER p-Value | 0.774 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 1225 | 0.169 | -0.0425 | No |
| 2 | NUDT21 | NUDT21 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 3927 | 0.061 | -0.2273 | No |
| 3 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 6709 | 0.004 | -0.4350 | No |
| 4 | CETN3 | CETN3 Entrez, Source | centrin, EF-hand protein, 3 (CDC31 homolog, yeast) | 6856 | 0.001 | -0.4456 | No |
| 5 | ALS2 | ALS2 Entrez, Source | amyotrophic lateral sclerosis 2 (juvenile) | 7100 | -0.004 | -0.4627 | No |
| 6 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 8204 | -0.028 | -0.5374 | No |
| 7 | MAP3K11 | MAP3K11 Entrez, Source | mitogen-activated protein kinase kinase kinase 11 | 8842 | -0.042 | -0.5729 | No |
| 8 | BRCA2 | BRCA2 Entrez, Source | breast cancer 2, early onset | 10026 | -0.075 | -0.6396 | Yes |
| 9 | PLK1 | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 10276 | -0.084 | -0.6338 | Yes |
| 10 | APC | APC Entrez, Source | adenomatosis polyposis coli | 10296 | -0.085 | -0.6104 | Yes |
| 11 | DCTN2 | DCTN2 Entrez, Source | dynactin 2 (p50) | 10303 | -0.085 | -0.5859 | Yes |
| 12 | CETN1 | CETN1 Entrez, Source | centrin, EF-hand protein, 1 | 10599 | -0.095 | -0.5802 | Yes |
| 13 | KATNB1 | KATNB1 Entrez, Source | katanin p80 (WD repeat containing) subunit B 1 | 10749 | -0.101 | -0.5618 | Yes |
| 14 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 11117 | -0.118 | -0.5548 | Yes |
| 15 | AKAP9 | AKAP9 Entrez, Source | A kinase (PRKA) anchor protein (yotiao) 9 | 11273 | -0.125 | -0.5296 | Yes |
| 16 | CDC16 | CDC16 Entrez, Source | CDC16 cell division cycle 16 homolog (S. cerevisiae) | 11467 | -0.135 | -0.5045 | Yes |
| 17 | TUBGCP3 | TUBGCP3 Entrez, Source | tubulin, gamma complex associated protein 3 | 11484 | -0.136 | -0.4657 | Yes |
| 18 | NDE1 | NDE1 Entrez, Source | nudE nuclear distribution gene E homolog 1 (A. nidulans) | 11603 | -0.144 | -0.4323 | Yes |
| 19 | CDC27 | CDC27 Entrez, Source | cell division cycle 27 | 11658 | -0.148 | -0.3931 | Yes |
| 20 | PCM1 | PCM1 Entrez, Source | pericentriolar material 1 | 11860 | -0.161 | -0.3609 | Yes |
| 21 | CDK5RAP2 | CDK5RAP2 Entrez, Source | CDK5 regulatory subunit associated protein 2 | 11990 | -0.172 | -0.3201 | Yes |
| 22 | TSGA14 | TSGA14 Entrez, Source | testis specific, 14 | 12175 | -0.189 | -0.2784 | Yes |
| 23 | DCTN4 | DCTN4 Entrez, Source | dynactin 4 (p62) | 12513 | -0.230 | -0.2360 | Yes |
| 24 | CKAP5 | CKAP5 Entrez, Source | cytoskeleton associated protein 5 | 12613 | -0.247 | -0.1708 | Yes |
| 25 | CLASP1 | CLASP1 Entrez, Source | cytoplasmic linker associated protein 1 | 12909 | -0.326 | -0.0974 | Yes |
| 26 | CEP57 | CEP57 Entrez, Source | centrosomal protein 57kDa | 13119 | -0.442 | 0.0167 | Yes |
