Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | CHANG_SERUM_RESPONSE_DN |
| Enrichment Score (ES) | 0.46449238 |
| Normalized Enrichment Score (NES) | 1.639438 |
| Nominal p-value | 0.004166667 |
| FDR q-value | 0.053005658 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | LPIN1 | LPIN1 Entrez, Source | lipin 1 | 43 | 0.774 | 0.0421 | Yes |
| 2 | INSIG1 | INSIG1 Entrez, Source | insulin induced gene 1 | 83 | 0.642 | 0.0768 | Yes |
| 3 | SCD | SCD Entrez, Source | stearoyl-CoA desaturase (delta-9-desaturase) | 84 | 0.641 | 0.1144 | Yes |
| 4 | FADS2 | FADS2 Entrez, Source | fatty acid desaturase 2 | 98 | 0.617 | 0.1496 | Yes |
| 5 | IDI1 | IDI1 Entrez, Source | isopentenyl-diphosphate delta isomerase 1 | 110 | 0.603 | 0.1841 | Yes |
| 6 | LSS | LSS Entrez, Source | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | 126 | 0.572 | 0.2165 | Yes |
| 7 | F10 | F10 Entrez, Source | coagulation factor X | 141 | 0.550 | 0.2477 | Yes |
| 8 | SQLE | SQLE Entrez, Source | squalene epoxidase | 188 | 0.485 | 0.2726 | Yes |
| 9 | HMGCS1 | HMGCS1 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) | 199 | 0.477 | 0.2998 | Yes |
| 10 | SC4MOL | SC4MOL Entrez, Source | sterol-C4-methyl oxidase-like | 284 | 0.409 | 0.3174 | Yes |
| 11 | FDPS | FDPS Entrez, Source | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | 315 | 0.386 | 0.3378 | Yes |
| 12 | MVD | MVD Entrez, Source | mevalonate (diphospho) decarboxylase | 328 | 0.380 | 0.3591 | Yes |
| 13 | POR | POR Entrez, Source | P450 (cytochrome) oxidoreductase | 384 | 0.346 | 0.3753 | Yes |
| 14 | FADS1 | FADS1 Entrez, Source | fatty acid desaturase 1 | 401 | 0.338 | 0.3939 | Yes |
| 15 | SLC40A1 | SLC40A1 Entrez, Source | solute carrier family 40 (iron-regulated transporter), member 1 | 500 | 0.300 | 0.4041 | Yes |
| 16 | SLC5A3 | SLC5A3 Entrez, Source | solute carrier family 5 (inositol transporters), member 3 | 565 | 0.279 | 0.4156 | Yes |
| 17 | CYP27A1 | CYP27A1 Entrez, Source | cytochrome P450, family 27, subfamily A, polypeptide 1 | 578 | 0.274 | 0.4308 | Yes |
| 18 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 581 | 0.272 | 0.4466 | Yes |
| 19 | LDLR | LDLR Entrez, Source | low density lipoprotein receptor (familial hypercholesterolemia) | 592 | 0.270 | 0.4616 | Yes |
| 20 | ATP6V0A1 | ATP6V0A1 Entrez, Source | ATPase, H+ transporting, lysosomal V0 subunit a1 | 869 | 0.212 | 0.4532 | Yes |
| 21 | CLIC2 | CLIC2 Entrez, Source | chloride intracellular channel 2 | 935 | 0.202 | 0.4602 | Yes |
| 22 | IL6ST | IL6ST Entrez, Source | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 1026 | 0.189 | 0.4645 | Yes |
| 23 | PDK2 | PDK2 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 2 | 1243 | 0.168 | 0.4580 | No |
| 24 | AXIN2 | AXIN2 Entrez, Source | axin 2 (conductin, axil) | 1488 | 0.151 | 0.4485 | No |
| 25 | CCNL2 | CCNL2 Entrez, Source | cyclin L2 | 1869 | 0.128 | 0.4273 | No |
| 26 | CNTNAP1 | CNTNAP1 Entrez, Source | contactin associated protein 1 | 2078 | 0.118 | 0.4186 | No |
| 27 | APOD | APOD Entrez, Source | apolipoprotein D | 2491 | 0.103 | 0.3935 | No |
| 28 | WBP2 | WBP2 Entrez, Source | WW domain binding protein 2 | 2728 | 0.095 | 0.3813 | No |
| 29 | IGBP1 | IGBP1 Entrez, Source | immunoglobulin (CD79A) binding protein 1 | 2784 | 0.092 | 0.3826 | No |
| 30 | SERPING1 | SERPING1 Entrez, Source | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) | 3378 | 0.074 | 0.3422 | No |
| 31 | GATM | GATM Entrez, Source | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 3691 | 0.067 | 0.3226 | No |
| 32 | CSF1 | CSF1 Entrez, Source | colony stimulating factor 1 (macrophage) | 3716 | 0.066 | 0.3247 | No |
| 33 | SFTPB | SFTPB Entrez, Source | surfactant, pulmonary-associated protein B | 3861 | 0.063 | 0.3175 | No |
| 34 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 4035 | 0.059 | 0.3079 | No |
| 35 | HDAC5 | HDAC5 Entrez, Source | histone deacetylase 5 | 4333 | 0.052 | 0.2886 | No |
| 36 | TNFSF12 | TNFSF12 Entrez, Source | tumor necrosis factor (ligand) superfamily, member 12 | 4529 | 0.048 | 0.2766 | No |
| 37 | MEF2D | MEF2D Entrez, Source | MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) | 4769 | 0.042 | 0.2611 | No |
| 38 | PTPRU | PTPRU Entrez, Source | protein tyrosine phosphatase, receptor type, U | 4946 | 0.039 | 0.2501 | No |
| 39 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 5634 | 0.025 | 0.1998 | No |
| 40 | PGCP | PGCP Entrez, Source | - | 7097 | -0.004 | 0.0898 | No |
| 41 | KIT | KIT Entrez, Source | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 7340 | -0.009 | 0.0721 | No |
| 42 | MBP | MBP Entrez, Source | myelin basic protein | 7470 | -0.012 | 0.0631 | No |
| 43 | WSB1 | WSB1 Entrez, Source | WD repeat and SOCS box-containing 1 | 7573 | -0.014 | 0.0562 | No |
| 44 | DNM1 | DNM1 Entrez, Source | dynamin 1 | 7697 | -0.017 | 0.0479 | No |
| 45 | PKIG | PKIG Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 7811 | -0.019 | 0.0405 | No |
| 46 | FCGRT | FCGRT Entrez, Source | Fc fragment of IgG, receptor, transporter, alpha | 8110 | -0.026 | 0.0196 | No |
| 47 | BBC3 | BBC3 Entrez, Source | BCL2 binding component 3 | 8410 | -0.033 | -0.0011 | No |
| 48 | LRP1 | LRP1 Entrez, Source | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 8598 | -0.037 | -0.0130 | No |
| 49 | LUM | LUM Entrez, Source | lumican | 8618 | -0.037 | -0.0123 | No |
| 50 | ADD3 | ADD3 Entrez, Source | adducin 3 (gamma) | 10162 | -0.080 | -0.1239 | No |
| 51 | NCOA3 | NCOA3 Entrez, Source | nuclear receptor coactivator 3 | 10363 | -0.087 | -0.1338 | No |
| 52 | CST3 | CST3 Entrez, Source | cystatin C (amyloid angiopathy and cerebral hemorrhage) | 10427 | -0.089 | -0.1333 | No |
| 53 | ITPKB | ITPKB Entrez, Source | inositol 1,4,5-trisphosphate 3-kinase B | 10615 | -0.096 | -0.1418 | No |
| 54 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 10631 | -0.096 | -0.1373 | No |
| 55 | MXI1 | MXI1 Entrez, Source | MAX interactor 1 | 10722 | -0.099 | -0.1383 | No |
| 56 | KLHL5 | KLHL5 Entrez, Source | kelch-like 5 (Drosophila) | 11028 | -0.113 | -0.1547 | No |
| 57 | ZNF219 | ZNF219 Entrez, Source | zinc finger protein 219 | 11170 | -0.120 | -0.1583 | No |
| 58 | CAMLG | CAMLG Entrez, Source | calcium modulating ligand | 11201 | -0.121 | -0.1534 | No |
| 59 | MFGE8 | MFGE8 Entrez, Source | milk fat globule-EGF factor 8 protein | 11372 | -0.130 | -0.1586 | No |
| 60 | APP | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 11404 | -0.131 | -0.1533 | No |
| 61 | TBRG1 | TBRG1 Entrez, Source | transforming growth factor beta regulator 1 | 11701 | -0.150 | -0.1668 | No |
| 62 | CTSF | CTSF Entrez, Source | cathepsin F | 11996 | -0.172 | -0.1789 | No |
| 63 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 12163 | -0.188 | -0.1804 | No |
| 64 | GABBR1 | GABBR1 Entrez, Source | gamma-aminobutyric acid (GABA) B receptor, 1 | 12170 | -0.189 | -0.1698 | No |
| 65 | GSN | GSN Entrez, Source | gelsolin (amyloidosis, Finnish type) | 12307 | -0.205 | -0.1680 | No |
| 66 | PLD3 | PLD3 Entrez, Source | phospholipase D family, member 3 | 12403 | -0.215 | -0.1625 | No |
| 67 | FABP3 | FABP3 Entrez, Source | fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) | 12473 | -0.224 | -0.1546 | No |
| 68 | REV3L | REV3L Entrez, Source | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 12493 | -0.227 | -0.1428 | No |
| 69 | SATB1 | SATB1 Entrez, Source | special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's) | 12659 | -0.255 | -0.1402 | No |
| 70 | PBXIP1 | PBXIP1 Entrez, Source | pre-B-cell leukemia transcription factor interacting protein 1 | 12721 | -0.269 | -0.1291 | No |
| 71 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 12725 | -0.270 | -0.1135 | No |
| 72 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 12840 | -0.300 | -0.1045 | No |
| 73 | GLS | GLS Entrez, Source | glutaminase | 13118 | -0.442 | -0.0995 | No |
| 74 | DPP7 | DPP7 Entrez, Source | dipeptidyl-peptidase 7 | 13210 | -0.577 | -0.0725 | No |
| 75 | TIMP2 | TIMP2 Entrez, Source | TIMP metallopeptidase inhibitor 2 | 13217 | -0.592 | -0.0383 | No |
| 76 | JAG1 | JAG1 Entrez, Source | jagged 1 (Alagille syndrome) | 13287 | -0.812 | 0.0041 | No |
