Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | CHIARETTI_T_ALL |
| Enrichment Score (ES) | -0.45361418 |
| Normalized Enrichment Score (NES) | -1.7427284 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.06555826 |
| FWER p-Value | 0.996 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 6 | 1.218 | 0.0467 | No |
| 2 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 192 | 0.482 | 0.0513 | No |
| 3 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 267 | 0.421 | 0.0620 | No |
| 4 | SC4MOL | SC4MOL Entrez, Source | sterol-C4-methyl oxidase-like | 284 | 0.409 | 0.0766 | No |
| 5 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 299 | 0.398 | 0.0910 | No |
| 6 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 335 | 0.375 | 0.1028 | No |
| 7 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 447 | 0.321 | 0.1069 | No |
| 8 | RGS1 | RGS1 Entrez, Source | regulator of G-protein signalling 1 | 510 | 0.296 | 0.1136 | No |
| 9 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 581 | 0.272 | 0.1189 | No |
| 10 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 720 | 0.235 | 0.1175 | No |
| 11 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 736 | 0.230 | 0.1253 | No |
| 12 | IFRD1 | IFRD1 Entrez, Source | interferon-related developmental regulator 1 | 837 | 0.215 | 0.1260 | No |
| 13 | CEBPB | CEBPB Entrez, Source | CCAAT/enhancer binding protein (C/EBP), beta | 862 | 0.212 | 0.1324 | No |
| 14 | BCL11A | BCL11A Entrez, Source | B-cell CLL/lymphoma 11A (zinc finger protein) | 875 | 0.211 | 0.1397 | No |
| 15 | ADFP | ADFP Entrez, Source | adipose differentiation-related protein | 1069 | 0.185 | 0.1322 | No |
| 16 | NFIL3 | NFIL3 Entrez, Source | nuclear factor, interleukin 3 regulated | 1319 | 0.163 | 0.1197 | No |
| 17 | TSHR | TSHR Entrez, Source | thyroid stimulating hormone receptor | 1351 | 0.160 | 0.1235 | No |
| 18 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 1414 | 0.156 | 0.1249 | No |
| 19 | CD97 | CD97 Entrez, Source | CD97 molecule | 1481 | 0.151 | 0.1257 | No |
| 20 | MAL | MAL Entrez, Source | mal, T-cell differentiation protein | 1572 | 0.144 | 0.1245 | No |
| 21 | HIST1H2BL | HIST1H2BL Entrez, Source | histone cluster 1, H2bl | 1720 | 0.136 | 0.1186 | No |
| 22 | PSPH | PSPH Entrez, Source | phosphoserine phosphatase | 1863 | 0.128 | 0.1128 | No |
| 23 | LMO4 | LMO4 Entrez, Source | LIM domain only 4 | 1984 | 0.122 | 0.1084 | No |
| 24 | ISG20 | ISG20 Entrez, Source | interferon stimulated exonuclease gene 20kDa | 2032 | 0.120 | 0.1095 | No |
| 25 | ALAS2 | ALAS2 Entrez, Source | aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | 2203 | 0.114 | 0.1011 | No |
| 26 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 2379 | 0.107 | 0.0920 | No |
| 27 | ST18 | ST18 Entrez, Source | suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein) | 2437 | 0.105 | 0.0917 | No |
| 28 | ARNTL | ARNTL Entrez, Source | aryl hydrocarbon receptor nuclear translocator-like | 2555 | 0.101 | 0.0868 | No |
| 29 | ZBTB16 | ZBTB16 Entrez, Source | zinc finger and BTB domain containing 16 | 2598 | 0.099 | 0.0874 | No |
| 30 | RUNX3 | RUNX3 Entrez, Source | runt-related transcription factor 3 | 2707 | 0.095 | 0.0829 | No |
| 31 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 2781 | 0.092 | 0.0810 | No |
| 32 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 2832 | 0.090 | 0.0807 | No |
| 33 | GUCY1A3 | GUCY1A3 Entrez, Source | guanylate cyclase 1, soluble, alpha 3 | 3179 | 0.079 | 0.0576 | No |
| 34 | PTTG1IP | PTTG1IP Entrez, Source | pituitary tumor-transforming 1 interacting protein | 3230 | 0.078 | 0.0568 | No |
| 35 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 3275 | 0.077 | 0.0564 | No |
| 36 | NOTCH3 | NOTCH3 Entrez, Source | Notch homolog 3 (Drosophila) | 3339 | 0.075 | 0.0545 | No |
| 37 | HES1 | HES1 Entrez, Source | hairy and enhancer of split 1, (Drosophila) | 3410 | 0.073 | 0.0521 | No |
| 38 | IGJ | IGJ Entrez, Source | immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides | 3441 | 0.073 | 0.0526 | No |
| 39 | SPON1 | SPON1 Entrez, Source | spondin 1, extracellular matrix protein | 3459 | 0.072 | 0.0541 | No |
| 40 | MINPP1 | MINPP1 Entrez, Source | multiple inositol polyphosphate histidine phosphatase, 1 | 3569 | 0.069 | 0.0485 | No |
| 41 | DUSP2 | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 3802 | 0.064 | 0.0334 | No |
| 42 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 3805 | 0.064 | 0.0358 | No |
| 43 | RCBTB2 | RCBTB2 Entrez, Source | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 3911 | 0.062 | 0.0302 | No |
| 44 | PLK2 | PLK2 Entrez, Source | polo-like kinase 2 (Drosophila) | 4002 | 0.059 | 0.0257 | No |
| 45 | ALOX5 | ALOX5 Entrez, Source | arachidonate 5-lipoxygenase | 4403 | 0.050 | -0.0027 | No |
| 46 | CD8A | CD8A Entrez, Source | CD8a molecule | 4554 | 0.047 | -0.0122 | No |
| 47 | IL4R | IL4R Entrez, Source | interleukin 4 receptor | 4588 | 0.047 | -0.0129 | No |
| 48 | SERPINE2 | SERPINE2 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 4745 | 0.043 | -0.0231 | No |
| 49 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 4819 | 0.041 | -0.0270 | No |
| 50 | IL12A | IL12A Entrez, Source | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) | 4872 | 0.040 | -0.0293 | No |
| 51 | CD2 | CD2 Entrez, Source | CD2 molecule | 4873 | 0.040 | -0.0278 | No |
| 52 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 4898 | 0.040 | -0.0281 | No |
| 53 | S100A9 | S100A9 Entrez, Source | S100 calcium binding protein A9 | 5107 | 0.036 | -0.0424 | No |
| 54 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 5560 | 0.026 | -0.0756 | No |
| 55 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 5634 | 0.025 | -0.0802 | No |
| 56 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 5855 | 0.021 | -0.0961 | No |
| 57 | FXYD2 | FXYD2 Entrez, Source | FXYD domain containing ion transport regulator 2 | 5862 | 0.021 | -0.0957 | No |
| 58 | GAB2 | GAB2 Entrez, Source | GRB2-associated binding protein 2 | 6013 | 0.018 | -0.1064 | No |
| 59 | PF4 | PF4 Entrez, Source | platelet factor 4 (chemokine (C-X-C motif) ligand 4) | 6018 | 0.018 | -0.1060 | No |
| 60 | NID2 | NID2 Entrez, Source | nidogen 2 (osteonidogen) | 6093 | 0.016 | -0.1109 | No |
| 61 | FGFR1 | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 6165 | 0.015 | -0.1157 | No |
| 62 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 6404 | 0.009 | -0.1334 | No |
| 63 | AQP3 | AQP3 Entrez, Source | aquaporin 3 (Gill blood group) | 6462 | 0.009 | -0.1374 | No |
| 64 | SLC4A1 | SLC4A1 Entrez, Source | solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) | 6479 | 0.008 | -0.1383 | No |
| 65 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 6556 | 0.007 | -0.1438 | No |
| 66 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 6561 | 0.007 | -0.1438 | No |
| 67 | SCG2 | SCG2 Entrez, Source | secretogranin II (chromogranin C) | 6564 | 0.007 | -0.1437 | No |
| 68 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 6602 | 0.006 | -0.1463 | No |
| 69 | PLAGL1 | PLAGL1 Entrez, Source | pleiomorphic adenoma gene-like 1 | 6668 | 0.005 | -0.1510 | No |
| 70 | SLC2A3 | SLC2A3 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 3 | 6683 | 0.004 | -0.1519 | No |
| 71 | ARID5A | ARID5A Entrez, Source | AT rich interactive domain 5A (MRF1-like) | 6828 | 0.002 | -0.1627 | No |
| 72 | RASGRP1 | RASGRP1 Entrez, Source | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 6836 | 0.002 | -0.1632 | No |
| 73 | CD200 | CD200 Entrez, Source | CD200 molecule | 6909 | 0.000 | -0.1687 | No |
| 74 | SNF1LK | SNF1LK Entrez, Source | SNF1-like kinase | 6978 | -0.002 | -0.1737 | No |
| 75 | CSDA | CSDA Entrez, Source | cold shock domain protein A | 7299 | -0.008 | -0.1977 | No |
| 76 | CD52 | CD52 Entrez, Source | CD52 molecule | 7395 | -0.010 | -0.2045 | No |
| 77 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 7461 | -0.012 | -0.2089 | No |
| 78 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 7521 | -0.013 | -0.2129 | No |
| 79 | TES | TES Entrez, Source | testis derived transcript (3 LIM domains) | 7914 | -0.021 | -0.2418 | No |
| 80 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 8322 | -0.030 | -0.2714 | No |
| 81 | LAT | LAT Entrez, Source | linker for activation of T cells | 8330 | -0.031 | -0.2708 | No |
| 82 | SELL | SELL Entrez, Source | selectin L (lymphocyte adhesion molecule 1) | 8569 | -0.036 | -0.2874 | No |
| 83 | KLF10 | KLF10 Entrez, Source | Kruppel-like factor 10 | 8626 | -0.037 | -0.2902 | No |
| 84 | STK17B | STK17B Entrez, Source | serine/threonine kinase 17b (apoptosis-inducing) | 9039 | -0.047 | -0.3196 | No |
| 85 | SKAP2 | SKAP2 Entrez, Source | src kinase associated phosphoprotein 2 | 9093 | -0.049 | -0.3217 | No |
| 86 | PTPRE | PTPRE Entrez, Source | protein tyrosine phosphatase, receptor type, E | 9160 | -0.050 | -0.3248 | No |
| 87 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 9270 | -0.054 | -0.3310 | No |
| 88 | CLEC11A | CLEC11A Entrez, Source | C-type lectin domain family 11, member A | 9373 | -0.057 | -0.3365 | No |
| 89 | PPBP | PPBP Entrez, Source | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 9692 | -0.065 | -0.3581 | No |
| 90 | ID1 | ID1 Entrez, Source | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 10098 | -0.078 | -0.3857 | No |
| 91 | TOB1 | TOB1 Entrez, Source | transducer of ERBB2, 1 | 10157 | -0.080 | -0.3870 | No |
| 92 | S100A8 | S100A8 Entrez, Source | S100 calcium binding protein A8 | 10280 | -0.084 | -0.3930 | No |
| 93 | LMO2 | LMO2 Entrez, Source | LIM domain only 2 (rhombotin-like 1) | 10340 | -0.086 | -0.3941 | No |
| 94 | HOXA5 | HOXA5 Entrez, Source | homeobox A5 | 10345 | -0.086 | -0.3911 | No |
| 95 | BUB1B | BUB1B Entrez, Source | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 10391 | -0.088 | -0.3911 | No |
| 96 | CXADR | CXADR Entrez, Source | coxsackie virus and adenovirus receptor | 10484 | -0.091 | -0.3945 | No |
| 97 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 10631 | -0.096 | -0.4019 | No |
| 98 | EMP3 | EMP3 Entrez, Source | epithelial membrane protein 3 | 10906 | -0.107 | -0.4185 | No |
| 99 | GARNL1 | GARNL1 Entrez, Source | GTPase activating Rap/RanGAP domain-like 1 | 10929 | -0.108 | -0.4160 | No |
| 100 | PDLIM1 | PDLIM1 Entrez, Source | PDZ and LIM domain 1 (elfin) | 10965 | -0.110 | -0.4144 | No |
| 101 | FHL1 | FHL1 Entrez, Source | four and a half LIM domains 1 | 10972 | -0.110 | -0.4106 | No |
| 102 | HHEX | HHEX Entrez, Source | homeobox, hematopoietically expressed | 11122 | -0.118 | -0.4173 | No |
| 103 | PRDX2 | PRDX2 Entrez, Source | peroxiredoxin 2 | 11173 | -0.120 | -0.4164 | No |
| 104 | H1F0 | H1F0 Entrez, Source | H1 histone family, member 0 | 11275 | -0.125 | -0.4192 | No |
| 105 | SFPQ | SFPQ Entrez, Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 11277 | -0.125 | -0.4144 | No |
| 106 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 11401 | -0.131 | -0.4187 | No |
| 107 | ITPR3 | ITPR3 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 3 | 11479 | -0.136 | -0.4193 | No |
| 108 | AHR | AHR Entrez, Source | aryl hydrocarbon receptor | 11529 | -0.139 | -0.4176 | No |
| 109 | CTSH | CTSH Entrez, Source | cathepsin H | 11951 | -0.169 | -0.4429 | No |
| 110 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 12093 | -0.181 | -0.4466 | Yes |
| 111 | LGALS1 | LGALS1 Entrez, Source | lectin, galactoside-binding, soluble, 1 (galectin 1) | 12094 | -0.181 | -0.4396 | Yes |
| 112 | WASF1 | WASF1 Entrez, Source | WAS protein family, member 1 | 12111 | -0.182 | -0.4337 | Yes |
| 113 | TAP1 | TAP1 Entrez, Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 12194 | -0.191 | -0.4326 | Yes |
| 114 | FRMD4B | FRMD4B Entrez, Source | FERM domain containing 4B | 12201 | -0.192 | -0.4256 | Yes |
| 115 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 12251 | -0.199 | -0.4216 | Yes |
| 116 | S100A10 | S100A10 Entrez, Source | S100 calcium binding protein A10 | 12432 | -0.219 | -0.4268 | Yes |
| 117 | ALCAM | ALCAM Entrez, Source | activated leukocyte cell adhesion molecule | 12557 | -0.237 | -0.4270 | Yes |
| 118 | PTGER4 | PTGER4 Entrez, Source | prostaglandin E receptor 4 (subtype EP4) | 12657 | -0.255 | -0.4246 | Yes |
| 119 | QKI | QKI Entrez, Source | quaking homolog, KH domain RNA binding (mouse) | 12675 | -0.260 | -0.4159 | Yes |
| 120 | S100A4 | S100A4 Entrez, Source | S100 calcium binding protein A4 | 12689 | -0.262 | -0.4067 | Yes |
| 121 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 12692 | -0.262 | -0.3967 | Yes |
| 122 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 12719 | -0.269 | -0.3883 | Yes |
| 123 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 12723 | -0.270 | -0.3781 | Yes |
| 124 | CLIC4 | CLIC4 Entrez, Source | chloride intracellular channel 4 | 12732 | -0.272 | -0.3682 | Yes |
| 125 | PCTK2 | PCTK2 Entrez, Source | PCTAIRE protein kinase 2 | 12886 | -0.316 | -0.3675 | Yes |
| 126 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 13016 | -0.374 | -0.3628 | Yes |
| 127 | EPHB6 | EPHB6 Entrez, Source | EPH receptor B6 | 13050 | -0.399 | -0.3499 | Yes |
| 128 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13077 | -0.411 | -0.3359 | Yes |
| 129 | SPRY2 | SPRY2 Entrez, Source | sprouty homolog 2 (Drosophila) | 13095 | -0.423 | -0.3209 | Yes |
| 130 | TSC22D3 | TSC22D3 Entrez, Source | TSC22 domain family, member 3 | 13117 | -0.441 | -0.3054 | Yes |
| 131 | CD69 | CD69 Entrez, Source | CD69 molecule | 13130 | -0.450 | -0.2889 | Yes |
| 132 | RAP2B | RAP2B Entrez, Source | RAP2B, member of RAS oncogene family | 13168 | -0.507 | -0.2721 | Yes |
| 133 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 13198 | -0.561 | -0.2525 | Yes |
| 134 | CTBP2 | CTBP2 Entrez, Source | C-terminal binding protein 2 | 13212 | -0.580 | -0.2311 | Yes |
| 135 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 13233 | -0.633 | -0.2081 | Yes |
| 136 | AHNAK | AHNAK Entrez, Source | AHNAK nucleoprotein (desmoyokin) | 13291 | -0.852 | -0.1795 | Yes |
| 137 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 13309 | -0.997 | -0.1422 | Yes |
| 138 | ARMCX2 | ARMCX2 Entrez, Source | armadillo repeat containing, X-linked 2 | 13310 | -1.005 | -0.1033 | Yes |
| 139 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13327 | -1.146 | -0.0601 | Yes |
| 140 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.581 | 0.0002 | Yes |
