Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | CITRATE_CYCLE_TCA_CYCLE |
| Enrichment Score (ES) | 0.6252672 |
| Normalized Enrichment Score (NES) | 1.5418559 |
| Nominal p-value | 0.04621849 |
| FDR q-value | 0.09917738 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PC | PC Entrez, Source | pyruvate carboxylase | 79 | 0.652 | 0.3109 | Yes |
| 2 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 167 | 0.505 | 0.5498 | Yes |
| 3 | IDH1 | IDH1 Entrez, Source | isocitrate dehydrogenase 1 (NADP+), soluble | 1183 | 0.172 | 0.5573 | Yes |
| 4 | DLD | DLD Entrez, Source | dihydrolipoamide dehydrogenase | 1628 | 0.141 | 0.5926 | Yes |
| 5 | MDH1 | MDH1 Entrez, Source | malate dehydrogenase 1, NAD (soluble) | 2361 | 0.108 | 0.5902 | Yes |
| 6 | SDHA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 2886 | 0.088 | 0.5938 | Yes |
| 7 | ACO1 | ACO1 Entrez, Source | aconitase 1, soluble | 3429 | 0.073 | 0.5886 | Yes |
| 8 | IDH3B | IDH3B Entrez, Source | isocitrate dehydrogenase 3 (NAD+) beta | 3545 | 0.070 | 0.6139 | Yes |
| 9 | MDH2 | MDH2 Entrez, Source | malate dehydrogenase 2, NAD (mitochondrial) | 4168 | 0.056 | 0.5943 | Yes |
| 10 | ACO2 | ACO2 Entrez, Source | aconitase 2, mitochondrial | 4353 | 0.052 | 0.6055 | Yes |
| 11 | SUCLG2 | SUCLG2 Entrez, Source | succinate-CoA ligase, GDP-forming, beta subunit | 4416 | 0.050 | 0.6253 | Yes |
| 12 | SUCLG1 | SUCLG1 Entrez, Source | succinate-CoA ligase, GDP-forming, alpha subunit | 5260 | 0.033 | 0.5779 | No |
| 13 | IDH3A | IDH3A Entrez, Source | isocitrate dehydrogenase 3 (NAD+) alpha | 6433 | 0.009 | 0.4944 | No |
| 14 | CS | CS Entrez, Source | citrate synthase | 7513 | -0.013 | 0.4195 | No |
| 15 | IDH3G | IDH3G Entrez, Source | isocitrate dehydrogenase 3 (NAD+) gamma | 8587 | -0.037 | 0.3568 | No |
