Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | CMV_24HRS_DN |
| Enrichment Score (ES) | -0.50954014 |
| Normalized Enrichment Score (NES) | -1.6556225 |
| Nominal p-value | 0.009803922 |
| FDR q-value | 0.09598693 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MBL2 | MBL2 Entrez, Source | mannose-binding lectin (protein C) 2, soluble (opsonic defect) | 263 | 0.424 | 0.0177 | No |
| 2 | HSD17B2 | HSD17B2 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 2 | 280 | 0.415 | 0.0531 | No |
| 3 | CXCL12 | CXCL12 Entrez, Source | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | 407 | 0.337 | 0.0734 | No |
| 4 | SULT1E1 | SULT1E1 Entrez, Source | sulfotransferase family 1E, estrogen-preferring, member 1 | 571 | 0.277 | 0.0856 | No |
| 5 | IGF2 | IGF2 Entrez, Source | insulin-like growth factor 2 (somatomedin A) | 867 | 0.212 | 0.0821 | No |
| 6 | PTGIS | PTGIS Entrez, Source | prostaglandin I2 (prostacyclin) synthase | 894 | 0.208 | 0.0985 | No |
| 7 | CDH11 | CDH11 Entrez, Source | cadherin 11, type 2, OB-cadherin (osteoblast) | 1034 | 0.189 | 0.1047 | No |
| 8 | EPO | EPO Entrez, Source | erythropoietin | 1097 | 0.182 | 0.1162 | No |
| 9 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 1920 | 0.125 | 0.0654 | No |
| 10 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 1938 | 0.125 | 0.0751 | No |
| 11 | COL6A2 | COL6A2 Entrez, Source | collagen, type VI, alpha 2 | 2097 | 0.118 | 0.0736 | No |
| 12 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 2222 | 0.114 | 0.0743 | No |
| 13 | CHN1 | CHN1 Entrez, Source | chimerin (chimaerin) 1 | 2335 | 0.109 | 0.0755 | No |
| 14 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 2467 | 0.104 | 0.0749 | No |
| 15 | TGFBR3 | TGFBR3 Entrez, Source | transforming growth factor, beta receptor III (betaglycan, 300kDa) | 2590 | 0.100 | 0.0745 | No |
| 16 | DDR2 | DDR2 Entrez, Source | discoidin domain receptor family, member 2 | 3366 | 0.074 | 0.0227 | No |
| 17 | ACO1 | ACO1 Entrez, Source | aconitase 1, soluble | 3429 | 0.073 | 0.0245 | No |
| 18 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 4105 | 0.057 | -0.0212 | No |
| 19 | CRHBP | CRHBP Entrez, Source | corticotropin releasing hormone binding protein | 4478 | 0.049 | -0.0449 | No |
| 20 | NR3C1 | NR3C1 Entrez, Source | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 4791 | 0.042 | -0.0647 | No |
| 21 | CFD | CFD Entrez, Source | complement factor D (adipsin) | 4814 | 0.042 | -0.0627 | No |
| 22 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 6077 | 0.017 | -0.1561 | No |
| 23 | ANPEP | ANPEP Entrez, Source | alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) | 6255 | 0.013 | -0.1683 | No |
| 24 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 7328 | -0.009 | -0.2482 | No |
| 25 | PDGFRA | PDGFRA Entrez, Source | platelet-derived growth factor receptor, alpha polypeptide | 7572 | -0.014 | -0.2653 | No |
| 26 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 8087 | -0.025 | -0.3017 | No |
| 27 | MATK | MATK Entrez, Source | megakaryocyte-associated tyrosine kinase | 8223 | -0.028 | -0.3094 | No |
| 28 | ADRA2A | ADRA2A Entrez, Source | adrenergic, alpha-2A-, receptor | 8458 | -0.033 | -0.3241 | No |
| 29 | EFEMP1 | EFEMP1 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 1 | 9375 | -0.057 | -0.3880 | No |
| 30 | PAFAH1B1 | PAFAH1B1 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa | 10819 | -0.104 | -0.4874 | No |
| 31 | C1R | C1R Entrez, Source | complement component 1, r subcomponent | 10987 | -0.111 | -0.4902 | No |
| 32 | CYP1B1 | CYP1B1 Entrez, Source | cytochrome P450, family 1, subfamily B, polypeptide 1 | 11000 | -0.112 | -0.4812 | No |
| 33 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 11212 | -0.122 | -0.4863 | No |
| 34 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 11420 | -0.132 | -0.4902 | No |
| 35 | AHR | AHR Entrez, Source | aryl hydrocarbon receptor | 11529 | -0.139 | -0.4861 | No |
| 36 | GPX1 | GPX1 Entrez, Source | glutathione peroxidase 1 | 11620 | -0.145 | -0.4801 | No |
| 37 | RAB13 | RAB13 Entrez, Source | RAB13, member RAS oncogene family | 11994 | -0.172 | -0.4929 | Yes |
| 38 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 12216 | -0.193 | -0.4925 | Yes |
| 39 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 12405 | -0.215 | -0.4876 | Yes |
| 40 | CXCR7 | CXCR7 Entrez, Source | chemokine (C-X-C motif) receptor 7 | 12489 | -0.226 | -0.4739 | Yes |
| 41 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 12760 | -0.277 | -0.4697 | Yes |
| 42 | ADM | ADM Entrez, Source | adrenomedullin | 12796 | -0.285 | -0.4472 | Yes |
| 43 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 12818 | -0.293 | -0.4229 | Yes |
| 44 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12897 | -0.319 | -0.4006 | Yes |
| 45 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 12902 | -0.323 | -0.3724 | Yes |
| 46 | RUNX1 | RUNX1 Entrez, Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 12949 | -0.338 | -0.3460 | Yes |
| 47 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12998 | -0.364 | -0.3174 | Yes |
| 48 | HIVEP2 | HIVEP2 Entrez, Source | human immunodeficiency virus type I enhancer binding protein 2 | 13020 | -0.376 | -0.2858 | Yes |
| 49 | TSPAN6 | TSPAN6 Entrez, Source | tetraspanin 6 | 13052 | -0.400 | -0.2528 | Yes |
| 50 | SGCG | SGCG Entrez, Source | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | 13113 | -0.440 | -0.2185 | Yes |
| 51 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13162 | -0.500 | -0.1780 | Yes |
| 52 | LAMB2 | LAMB2 Entrez, Source | laminin, beta 2 (laminin S) | 13313 | -1.021 | -0.0991 | Yes |
| 53 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13327 | -1.146 | 0.0011 | Yes |
