Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | COENZYME_METABOLIC_PROCESS |
| Enrichment Score (ES) | 0.7924493 |
| Normalized Enrichment Score (NES) | 2.1509044 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.8160118E-4 |
| FWER p-Value | 0.01 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FTCD | FTCD Entrez, Source | formiminotransferase cyclodeaminase | 9 | 1.171 | 0.1953 | Yes |
| 2 | GLYAT | GLYAT Entrez, Source | glycine-N-acyltransferase | 10 | 1.121 | 0.3828 | Yes |
| 3 | ACLY | ACLY Entrez, Source | ATP citrate lyase | 186 | 0.487 | 0.4511 | Yes |
| 4 | ACOT12 | ACOT12 Entrez, Source | acyl-CoA thioesterase 12 | 212 | 0.461 | 0.5264 | Yes |
| 5 | ACOT2 | ACOT2 Entrez, Source | acyl-CoA thioesterase 2 | 231 | 0.450 | 0.6004 | Yes |
| 6 | MOCS2 | MOCS2 Entrez, Source | molybdenum cofactor synthesis 2 | 352 | 0.361 | 0.6518 | Yes |
| 7 | MLYCD | MLYCD Entrez, Source | malonyl-CoA decarboxylase | 584 | 0.271 | 0.6799 | Yes |
| 8 | ALDH1L1 | ALDH1L1 Entrez, Source | aldehyde dehydrogenase 1 family, member L1 | 750 | 0.228 | 0.7055 | Yes |
| 9 | PDHB | PDHB Entrez, Source | pyruvate dehydrogenase (lipoamide) beta | 858 | 0.213 | 0.7331 | Yes |
| 10 | COQ3 | COQ3 Entrez, Source | coenzyme Q3 homolog, methyltransferase (S. cerevisiae) | 932 | 0.202 | 0.7614 | Yes |
| 11 | SDHD | SDHD Entrez, Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 1404 | 0.157 | 0.7523 | Yes |
| 12 | COQ7 | COQ7 Entrez, Source | coenzyme Q7 homolog, ubiquinone (yeast) | 1476 | 0.151 | 0.7722 | Yes |
| 13 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1535 | 0.147 | 0.7924 | Yes |
| 14 | SDHA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 2886 | 0.088 | 0.7059 | No |
| 15 | COASY | COASY Entrez, Source | Coenzyme A synthase | 3537 | 0.070 | 0.6688 | No |
| 16 | GLRX2 | GLRX2 Entrez, Source | glutaredoxin 2 | 3592 | 0.069 | 0.6763 | No |
| 17 | SDHC | SDHC Entrez, Source | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 3898 | 0.062 | 0.6638 | No |
| 18 | ACO2 | ACO2 Entrez, Source | aconitase 2, mitochondrial | 4353 | 0.052 | 0.6383 | No |
| 19 | GCLC | GCLC Entrez, Source | glutamate-cysteine ligase, catalytic subunit | 6525 | 0.007 | 0.4765 | No |
| 20 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 7856 | -0.020 | 0.3800 | No |
| 21 | GCLM | GCLM Entrez, Source | glutamate-cysteine ligase, modifier subunit | 8939 | -0.045 | 0.3062 | No |
| 22 | GPX1 | GPX1 Entrez, Source | glutathione peroxidase 1 | 11620 | -0.145 | 0.1293 | No |
