Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | CROMER_HYPOPHARYNGEAL_MET_VS_NON_DN |
| Enrichment Score (ES) | -0.628058 |
| Normalized Enrichment Score (NES) | -1.9333816 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.019567639 |
| FWER p-Value | 0.319 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EPAS1 | EPAS1 Entrez, Source | endothelial PAS domain protein 1 | 871 | 0.211 | -0.0359 | No |
| 2 | AFG3L2 | AFG3L2 Entrez, Source | AFG3 ATPase family gene 3-like 2 (yeast) | 1449 | 0.153 | -0.0578 | No |
| 3 | TNNT3 | TNNT3 Entrez, Source | troponin T type 3 (skeletal, fast) | 2118 | 0.117 | -0.0916 | No |
| 4 | FLNB | FLNB Entrez, Source | filamin B, beta (actin binding protein 278) | 3317 | 0.076 | -0.1711 | No |
| 5 | KLK10 | KLK10 Entrez, Source | kallikrein 10 | 3478 | 0.072 | -0.1730 | No |
| 6 | IMPA2 | IMPA2 Entrez, Source | inositol(myo)-1(or 4)-monophosphatase 2 | 3887 | 0.062 | -0.1950 | No |
| 7 | ATP5A1 | ATP5A1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle | 3895 | 0.062 | -0.1868 | No |
| 8 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 4054 | 0.058 | -0.1905 | No |
| 9 | VSNL1 | VSNL1 Entrez, Source | visinin-like 1 | 4526 | 0.048 | -0.2192 | No |
| 10 | SDC4 | SDC4 Entrez, Source | syndecan 4 (amphiglycan, ryudocan) | 4826 | 0.041 | -0.2359 | No |
| 11 | ATP5D | ATP5D Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit | 5013 | 0.038 | -0.2446 | No |
| 12 | PRODH | PRODH Entrez, Source | proline dehydrogenase (oxidase) 1 | 5569 | 0.026 | -0.2826 | No |
| 13 | MALL | MALL Entrez, Source | mal, T-cell differentiation protein-like | 6872 | 0.001 | -0.3804 | No |
| 14 | VDAC3 | VDAC3 Entrez, Source | voltage-dependent anion channel 3 | 7025 | -0.003 | -0.3915 | No |
| 15 | PSMD8 | PSMD8 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 7178 | -0.006 | -0.4021 | No |
| 16 | PA2G4 | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 8877 | -0.043 | -0.5237 | No |
| 17 | PPP4C | PPP4C Entrez, Source | protein phosphatase 4 (formerly X), catalytic subunit | 8977 | -0.045 | -0.5248 | No |
| 18 | BMP1 | BMP1 Entrez, Source | bone morphogenetic protein 1 | 9411 | -0.057 | -0.5493 | No |
| 19 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 9745 | -0.066 | -0.5651 | No |
| 20 | ZC3H8 | ZC3H8 Entrez, Source | zinc finger CCCH-type containing 8 | 10584 | -0.095 | -0.6148 | Yes |
| 21 | SLC20A2 | SLC20A2 Entrez, Source | solute carrier family 20 (phosphate transporter), member 2 | 10687 | -0.098 | -0.6087 | Yes |
| 22 | PLEC1 | PLEC1 Entrez, Source | plectin 1, intermediate filament binding protein 500kDa | 10694 | -0.098 | -0.5954 | Yes |
| 23 | SERPINB5 | SERPINB5 Entrez, Source | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 10823 | -0.104 | -0.5904 | Yes |
| 24 | FXYD3 | FXYD3 Entrez, Source | FXYD domain containing ion transport regulator 3 | 10861 | -0.105 | -0.5785 | Yes |
| 25 | ST6GALNAC2 | ST6GALNAC2 Entrez, Source | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 11077 | -0.115 | -0.5785 | Yes |
| 26 | SMTN | SMTN Entrez, Source | smoothelin | 11525 | -0.139 | -0.5926 | Yes |
| 27 | BAIAP2 | BAIAP2 Entrez, Source | BAI1-associated protein 2 | 11565 | -0.141 | -0.5758 | Yes |
| 28 | DUSP7 | DUSP7 Entrez, Source | dual specificity phosphatase 7 | 11765 | -0.153 | -0.5692 | Yes |
| 29 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 11774 | -0.155 | -0.5481 | Yes |
| 30 | ITGB4 | ITGB4 Entrez, Source | integrin, beta 4 | 11844 | -0.160 | -0.5309 | Yes |
| 31 | GJB3 | GJB3 Entrez, Source | gap junction protein, beta 3, 31kDa (connexin 31) | 12077 | -0.180 | -0.5232 | Yes |
| 32 | CAV2 | CAV2 Entrez, Source | caveolin 2 | 12113 | -0.183 | -0.5002 | Yes |
| 33 | HSPA2 | HSPA2 Entrez, Source | heat shock 70kDa protein 2 | 12146 | -0.186 | -0.4766 | Yes |
| 34 | SH3GL1 | SH3GL1 Entrez, Source | SH3-domain GRB2-like 1 | 12238 | -0.197 | -0.4557 | Yes |
| 35 | LMNA | LMNA Entrez, Source | lamin A/C | 12337 | -0.209 | -0.4338 | Yes |
| 36 | JUP | JUP Entrez, Source | junction plakoglobin | 12351 | -0.210 | -0.4054 | Yes |
| 37 | S100A11 | S100A11 Entrez, Source | S100 calcium binding protein A11 | 12634 | -0.251 | -0.3914 | Yes |
| 38 | DTX2 | DTX2 Entrez, Source | deltex homolog 2 (Drosophila) | 12704 | -0.265 | -0.3594 | Yes |
| 39 | CKB | CKB Entrez, Source | creatine kinase, brain | 12974 | -0.349 | -0.3307 | Yes |
| 40 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 13154 | -0.487 | -0.2759 | Yes |
| 41 | TPBG | TPBG Entrez, Source | trophoblast glycoprotein | 13155 | -0.487 | -0.2077 | Yes |
| 42 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.581 | 0.0002 | Yes |
