Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | DNA_REPLICATION_REACTOME |
| Enrichment Score (ES) | -0.5929539 |
| Normalized Enrichment Score (NES) | -1.6132946 |
| Nominal p-value | 0.0077669905 |
| FDR q-value | 0.111231446 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | POLD4 | POLD4 Entrez, Source | polymerase (DNA-directed), delta 4 | 294 | 0.400 | 0.0747 | No |
| 2 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 3808 | 0.064 | -0.1737 | No |
| 3 | UBC | UBC Entrez, Source | ubiquitin C | 4204 | 0.055 | -0.1900 | No |
| 4 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 4626 | 0.046 | -0.2106 | No |
| 5 | ORC2L | ORC2L Entrez, Source | origin recognition complex, subunit 2-like (yeast) | 5273 | 0.032 | -0.2512 | No |
| 6 | ORC4L | ORC4L Entrez, Source | origin recognition complex, subunit 4-like (yeast) | 6443 | 0.009 | -0.3369 | No |
| 7 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 8707 | -0.039 | -0.4973 | No |
| 8 | UBA52 | UBA52 Entrez, Source | ubiquitin A-52 residue ribosomal protein fusion product 1 | 8757 | -0.040 | -0.4913 | No |
| 9 | RPS27A | RPS27A Entrez, Source | ribosomal protein S27a | 8887 | -0.043 | -0.4905 | No |
| 10 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 9233 | -0.052 | -0.5038 | No |
| 11 | UBB | UBB Entrez, Source | ubiquitin B | 10179 | -0.081 | -0.5553 | No |
| 12 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 10651 | -0.097 | -0.5672 | Yes |
| 13 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 10774 | -0.102 | -0.5517 | Yes |
| 14 | POLD2 | POLD2 Entrez, Source | polymerase (DNA directed), delta 2, regulatory subunit 50kDa | 11324 | -0.128 | -0.5621 | Yes |
| 15 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 11589 | -0.143 | -0.5474 | Yes |
| 16 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 11672 | -0.148 | -0.5178 | Yes |
| 17 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 11987 | -0.172 | -0.4998 | Yes |
| 18 | ORC3L | ORC3L Entrez, Source | origin recognition complex, subunit 3-like (yeast) | 12302 | -0.205 | -0.4738 | Yes |
| 19 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 12498 | -0.229 | -0.4332 | Yes |
| 20 | ORC6L | ORC6L Entrez, Source | origin recognition complex, subunit 6 like (yeast) | 12525 | -0.232 | -0.3790 | Yes |
| 21 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 12611 | -0.247 | -0.3257 | Yes |
| 22 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12999 | -0.364 | -0.2667 | Yes |
| 23 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13028 | -0.381 | -0.1768 | Yes |
| 24 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13289 | -0.828 | 0.0040 | Yes |
