Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | ELECTRON_CARRIER_ACTIVITY |
| Enrichment Score (ES) | 0.5147742 |
| Normalized Enrichment Score (NES) | 1.6994048 |
| Nominal p-value | 0.0042462847 |
| FDR q-value | 0.03305892 |
| FWER p-Value | 0.998 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DMGDH | DMGDH Entrez, Source | dimethylglycine dehydrogenase | 128 | 0.569 | 0.0710 | Yes |
| 2 | KMO | KMO Entrez, Source | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 174 | 0.497 | 0.1381 | Yes |
| 3 | HAAO | HAAO Entrez, Source | 3-hydroxyanthranilate 3,4-dioxygenase | 196 | 0.479 | 0.2044 | Yes |
| 4 | SARDH | SARDH Entrez, Source | sarcosine dehydrogenase | 245 | 0.438 | 0.2628 | Yes |
| 5 | SRD5A1 | SRD5A1 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 343 | 0.371 | 0.3080 | Yes |
| 6 | ETFDH | ETFDH Entrez, Source | electron-transferring-flavoprotein dehydrogenase | 363 | 0.357 | 0.3572 | Yes |
| 7 | POR | POR Entrez, Source | P450 (cytochrome) oxidoreductase | 384 | 0.346 | 0.4048 | Yes |
| 8 | PHYH | PHYH Entrez, Source | phytanoyl-CoA 2-hydroxylase | 849 | 0.214 | 0.4002 | Yes |
| 9 | ETFB | ETFB Entrez, Source | electron-transfer-flavoprotein, beta polypeptide | 865 | 0.212 | 0.4291 | Yes |
| 10 | NQO2 | NQO2 Entrez, Source | NAD(P)H dehydrogenase, quinone 2 | 1174 | 0.173 | 0.4305 | Yes |
| 11 | SDHD | SDHD Entrez, Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 1404 | 0.157 | 0.4354 | Yes |
| 12 | PHGDH | PHGDH Entrez, Source | phosphoglycerate dehydrogenase | 1496 | 0.150 | 0.4499 | Yes |
| 13 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1535 | 0.147 | 0.4678 | Yes |
| 14 | HMOX2 | HMOX2 Entrez, Source | heme oxygenase (decycling) 2 | 1546 | 0.146 | 0.4877 | Yes |
| 15 | DLD | DLD Entrez, Source | dihydrolipoamide dehydrogenase | 1628 | 0.141 | 0.5017 | Yes |
| 16 | MAOB | MAOB Entrez, Source | monoamine oxidase B | 1712 | 0.137 | 0.5148 | Yes |
| 17 | TXNRD2 | TXNRD2 Entrez, Source | thioredoxin reductase 2 | 2200 | 0.114 | 0.4943 | No |
| 18 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 2402 | 0.107 | 0.4943 | No |
| 19 | ETFA | ETFA Entrez, Source | electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II) | 2650 | 0.098 | 0.4896 | No |
| 20 | NDUFS7 | NDUFS7 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 2674 | 0.096 | 0.5015 | No |
| 21 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 2909 | 0.088 | 0.4963 | No |
| 22 | NDUFS2 | NDUFS2 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | 2926 | 0.087 | 0.5075 | No |
| 23 | AKR7A2 | AKR7A2 Entrez, Source | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 3278 | 0.077 | 0.4919 | No |
| 24 | CYB5R2 | CYB5R2 Entrez, Source | cytochrome b5 reductase 2 | 3428 | 0.073 | 0.4911 | No |
| 25 | IDH3B | IDH3B Entrez, Source | isocitrate dehydrogenase 3 (NAD+) beta | 3545 | 0.070 | 0.4922 | No |
| 26 | MTRR | MTRR Entrez, Source | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | 3648 | 0.068 | 0.4941 | No |
| 27 | GSR | GSR Entrez, Source | glutathione reductase | 4018 | 0.059 | 0.4747 | No |
| 28 | CYP1A2 | CYP1A2 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 2 | 4085 | 0.058 | 0.4779 | No |
| 29 | QDPR | QDPR Entrez, Source | quinoid dihydropteridine reductase | 4665 | 0.045 | 0.4407 | No |
| 30 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 5320 | 0.032 | 0.3960 | No |
| 31 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 5395 | 0.030 | 0.3947 | No |
| 32 | COX5A | COX5A Entrez, Source | cytochrome c oxidase subunit Va | 5800 | 0.022 | 0.3674 | No |
| 33 | AKR7A3 | AKR7A3 Entrez, Source | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 5906 | 0.020 | 0.3624 | No |
| 34 | NCF1 | NCF1 Entrez, Source | neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) | 6242 | 0.013 | 0.3390 | No |
| 35 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 6279 | 0.012 | 0.3381 | No |
| 36 | NDUFS4 | NDUFS4 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 6477 | 0.008 | 0.3244 | No |
| 37 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 6602 | 0.006 | 0.3159 | No |
| 38 | NDUFA9 | NDUFA9 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa | 6665 | 0.005 | 0.3119 | No |
| 39 | NOX4 | NOX4 Entrez, Source | NADPH oxidase 4 | 6694 | 0.004 | 0.3104 | No |
| 40 | NQO1 | NQO1 Entrez, Source | NAD(P)H dehydrogenase, quinone 1 | 6707 | 0.004 | 0.3101 | No |
| 41 | FDXR | FDXR Entrez, Source | ferredoxin reductase | 7908 | -0.021 | 0.2228 | No |
| 42 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 8124 | -0.026 | 0.2103 | No |
| 43 | GPX2 | GPX2 Entrez, Source | glutathione peroxidase 2 (gastrointestinal) | 8597 | -0.037 | 0.1800 | No |
| 44 | CYB5R3 | CYB5R3 Entrez, Source | cytochrome b5 reductase 3 | 8840 | -0.042 | 0.1678 | No |
| 45 | DEGS1 | DEGS1 Entrez, Source | degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) | 10024 | -0.075 | 0.0894 | No |
| 46 | CYB5R4 | CYB5R4 Entrez, Source | cytochrome b5 reductase 4 | 10050 | -0.076 | 0.0983 | No |
| 47 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 10743 | -0.100 | 0.0604 | No |
| 48 | FDX1 | FDX1 Entrez, Source | ferredoxin 1 | 10969 | -0.110 | 0.0591 | No |
| 49 | UGDH | UGDH Entrez, Source | UDP-glucose dehydrogenase | 11033 | -0.113 | 0.0704 | No |
| 50 | TXNRD1 | TXNRD1 Entrez, Source | thioredoxin reductase 1 | 11903 | -0.166 | 0.0285 | No |
| 51 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 12291 | -0.203 | 0.0282 | No |
| 52 | CYBA | CYBA Entrez, Source | cytochrome b-245, alpha polypeptide | 12989 | -0.359 | 0.0266 | No |
