Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | ELECTRON_TRANSPORT_GO_0006118 |
| Enrichment Score (ES) | 0.547006 |
| Normalized Enrichment Score (NES) | 1.5545557 |
| Nominal p-value | 0.015350877 |
| FDR q-value | 0.09219745 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 50 | 0.751 | 0.1891 | Yes |
| 2 | CDO1 | CDO1 Entrez, Source | cysteine dioxygenase, type I | 104 | 0.612 | 0.3421 | Yes |
| 3 | POR | POR Entrez, Source | P450 (cytochrome) oxidoreductase | 384 | 0.346 | 0.4101 | Yes |
| 4 | AKR1D1 | AKR1D1 Entrez, Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 656 | 0.251 | 0.4543 | Yes |
| 5 | PDIA5 | PDIA5 Entrez, Source | protein disulfide isomerase family A, member 5 | 864 | 0.212 | 0.4931 | Yes |
| 6 | ALDH5A1 | ALDH5A1 Entrez, Source | aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 870 | 0.211 | 0.5470 | Yes |
| 7 | DHRS4 | DHRS4 Entrez, Source | dehydrogenase/reductase (SDR family) member 4 | 1941 | 0.124 | 0.4986 | No |
| 8 | SPR | SPR Entrez, Source | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 2551 | 0.101 | 0.4788 | No |
| 9 | SDHA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 2886 | 0.088 | 0.4765 | No |
| 10 | SURF1 | SURF1 Entrez, Source | surfeit 1 | 3098 | 0.082 | 0.4816 | No |
| 11 | CYB5R2 | CYB5R2 Entrez, Source | cytochrome b5 reductase 2 | 3428 | 0.073 | 0.4756 | No |
| 12 | MTRR | MTRR Entrez, Source | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | 3648 | 0.068 | 0.4765 | No |
| 13 | SDHC | SDHC Entrez, Source | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 3898 | 0.062 | 0.4738 | No |
| 14 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 4305 | 0.053 | 0.4568 | No |
| 15 | UQCRC1 | UQCRC1 Entrez, Source | ubiquinol-cytochrome c reductase core protein I | 4861 | 0.041 | 0.4256 | No |
| 16 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 4870 | 0.040 | 0.4353 | No |
| 17 | BLVRA | BLVRA Entrez, Source | biliverdin reductase A | 4973 | 0.038 | 0.4375 | No |
| 18 | DUOX2 | DUOX2 Entrez, Source | dual oxidase 2 | 6346 | 0.011 | 0.3372 | No |
| 19 | NOX4 | NOX4 Entrez, Source | NADPH oxidase 4 | 6694 | 0.004 | 0.3123 | No |
| 20 | GPX4 | GPX4 Entrez, Source | glutathione peroxidase 4 (phospholipid hydroperoxidase) | 6721 | 0.004 | 0.3113 | No |
| 21 | RETSAT | RETSAT Entrez, Source | retinol saturase (all-trans-retinol 13,14-reductase) | 6880 | 0.001 | 0.2996 | No |
| 22 | TXNL1 | TXNL1 Entrez, Source | thioredoxin-like 1 | 7208 | -0.006 | 0.2767 | No |
| 23 | FDXR | FDXR Entrez, Source | ferredoxin reductase | 7908 | -0.021 | 0.2297 | No |
| 24 | PLOD1 | PLOD1 Entrez, Source | procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1 | 10791 | -0.102 | 0.0395 | No |
| 25 | CYP1B1 | CYP1B1 Entrez, Source | cytochrome P450, family 1, subfamily B, polypeptide 1 | 11000 | -0.112 | 0.0526 | No |
| 26 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 11983 | -0.171 | 0.0229 | No |
| 27 | LOXL1 | LOXL1 Entrez, Source | lysyl oxidase-like 1 | 12864 | -0.308 | 0.0359 | No |
