Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | ESR_FIBROBLAST_UP |
| Enrichment Score (ES) | -0.5911252 |
| Normalized Enrichment Score (NES) | -1.7586486 |
| Nominal p-value | 0.005882353 |
| FDR q-value | 0.060687695 |
| FWER p-Value | 0.986 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 267 | 0.421 | 0.0570 | No |
| 2 | TXNRD2 | TXNRD2 Entrez, Source | thioredoxin reductase 2 | 2200 | 0.114 | -0.0673 | No |
| 3 | ZFP36L1 | ZFP36L1 Entrez, Source | zinc finger protein 36, C3H type-like 1 | 2292 | 0.111 | -0.0538 | No |
| 4 | MARK3 | MARK3 Entrez, Source | MAP/microtubule affinity-regulating kinase 3 | 3431 | 0.073 | -0.1260 | No |
| 5 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 3872 | 0.063 | -0.1476 | No |
| 6 | ATP5I | ATP5I Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E | 3963 | 0.061 | -0.1433 | No |
| 7 | BNIP3L | BNIP3L Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 4011 | 0.059 | -0.1360 | No |
| 8 | TBCA | TBCA Entrez, Source | tubulin-specific chaperone a | 4542 | 0.047 | -0.1671 | No |
| 9 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 5084 | 0.036 | -0.2012 | No |
| 10 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 5186 | 0.034 | -0.2025 | No |
| 11 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 5320 | 0.032 | -0.2067 | No |
| 12 | HGF | HGF Entrez, Source | hepatocyte growth factor (hepapoietin A; scatter factor) | 5893 | 0.020 | -0.2459 | No |
| 13 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 6115 | 0.016 | -0.2596 | No |
| 14 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 6247 | 0.013 | -0.2671 | No |
| 15 | EFNB1 | EFNB1 Entrez, Source | ephrin-B1 | 7378 | -0.010 | -0.3502 | No |
| 16 | FGFR4 | FGFR4 Entrez, Source | fibroblast growth factor receptor 4 | 7668 | -0.016 | -0.3690 | No |
| 17 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 7856 | -0.020 | -0.3794 | No |
| 18 | GOLPH3 | GOLPH3 Entrez, Source | golgi phosphoprotein 3 (coat-protein) | 7961 | -0.023 | -0.3831 | No |
| 19 | OAZ1 | OAZ1 Entrez, Source | ornithine decarboxylase antizyme 1 | 9397 | -0.057 | -0.4805 | No |
| 20 | FN1 | FN1 Entrez, Source | fibronectin 1 | 9917 | -0.072 | -0.5063 | No |
| 21 | EIF3S6IP | EIF3S6IP Entrez, Source | eukaryotic translation initiation factor 3, subunit 6 interacting protein | 10010 | -0.075 | -0.4995 | No |
| 22 | FLOT1 | FLOT1 Entrez, Source | flotillin 1 | 10070 | -0.077 | -0.4899 | No |
| 23 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 10143 | -0.079 | -0.4807 | No |
| 24 | ARPC1B | ARPC1B Entrez, Source | actin related protein 2/3 complex, subunit 1B, 41kDa | 10374 | -0.087 | -0.4820 | No |
| 25 | TPR | TPR Entrez, Source | translocated promoter region (to activated MET oncogene) | 10496 | -0.091 | -0.4744 | No |
| 26 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 11278 | -0.125 | -0.5101 | No |
| 27 | PRDX4 | PRDX4 Entrez, Source | peroxiredoxin 4 | 11707 | -0.150 | -0.5149 | No |
| 28 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 12723 | -0.270 | -0.5418 | Yes |
| 29 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 12902 | -0.323 | -0.4960 | Yes |
| 30 | NGFRAP1 | NGFRAP1 Entrez, Source | nerve growth factor receptor (TNFRSF16) associated protein 1 | 13127 | -0.447 | -0.4311 | Yes |
| 31 | VIM | VIM Entrez, Source | vimentin | 13164 | -0.501 | -0.3420 | Yes |
| 32 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 13282 | -0.795 | -0.2053 | Yes |
| 33 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13327 | -1.146 | 0.0011 | Yes |
