Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | ET743_HELA_UP |
| Enrichment Score (ES) | -0.5759756 |
| Normalized Enrichment Score (NES) | -1.7418895 |
| Nominal p-value | 0.009416196 |
| FDR q-value | 0.06464474 |
| FWER p-Value | 0.997 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CBS | CBS Entrez, Source | cystathionine-beta-synthase | 158 | 0.523 | 0.0384 | No |
| 2 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 383 | 0.346 | 0.0549 | No |
| 3 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 417 | 0.334 | 0.0845 | No |
| 4 | PHYH | PHYH Entrez, Source | phytanoyl-CoA 2-hydroxylase | 849 | 0.214 | 0.0727 | No |
| 5 | TGFBI | TGFBI Entrez, Source | transforming growth factor, beta-induced, 68kDa | 1217 | 0.169 | 0.0614 | No |
| 6 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 1414 | 0.156 | 0.0616 | No |
| 7 | PROS1 | PROS1 Entrez, Source | protein S (alpha) | 2217 | 0.114 | 0.0123 | No |
| 8 | ASNS | ASNS Entrez, Source | asparagine synthetase | 2424 | 0.106 | 0.0070 | No |
| 9 | FOLR1 | FOLR1 Entrez, Source | folate receptor 1 (adult) | 2549 | 0.101 | 0.0074 | No |
| 10 | CLDN7 | CLDN7 Entrez, Source | claudin 7 | 2563 | 0.101 | 0.0161 | No |
| 11 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 2909 | 0.088 | -0.0014 | No |
| 12 | CASP4 | CASP4 Entrez, Source | caspase 4, apoptosis-related cysteine peptidase | 3096 | 0.082 | -0.0075 | No |
| 13 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 3320 | 0.076 | -0.0170 | No |
| 14 | DDR2 | DDR2 Entrez, Source | discoidin domain receptor family, member 2 | 3366 | 0.074 | -0.0133 | No |
| 15 | CFD | CFD Entrez, Source | complement factor D (adipsin) | 4814 | 0.042 | -0.1181 | No |
| 16 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 4898 | 0.040 | -0.1205 | No |
| 17 | FGG | FGG Entrez, Source | fibrinogen gamma chain | 4933 | 0.039 | -0.1192 | No |
| 18 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 5204 | 0.034 | -0.1363 | No |
| 19 | GARS | GARS Entrez, Source | glycyl-tRNA synthetase | 5484 | 0.028 | -0.1545 | No |
| 20 | EML2 | EML2 Entrez, Source | echinoderm microtubule associated protein like 2 | 5714 | 0.023 | -0.1695 | No |
| 21 | NID2 | NID2 Entrez, Source | nidogen 2 (osteonidogen) | 6093 | 0.016 | -0.1964 | No |
| 22 | NUCB2 | NUCB2 Entrez, Source | nucleobindin 2 | 8348 | -0.031 | -0.3628 | No |
| 23 | CASP9 | CASP9 Entrez, Source | caspase 9, apoptosis-related cysteine peptidase | 8748 | -0.040 | -0.3890 | No |
| 24 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 9083 | -0.048 | -0.4095 | No |
| 25 | ARL6IP1 | ARL6IP1 Entrez, Source | ADP-ribosylation factor-like 6 interacting protein 1 | 9427 | -0.058 | -0.4297 | No |
| 26 | AES | AES Entrez, Source | amino-terminal enhancer of split | 9813 | -0.069 | -0.4520 | No |
| 27 | GSTA4 | GSTA4 Entrez, Source | glutathione S-transferase A4 | 9961 | -0.073 | -0.4560 | No |
| 28 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 10123 | -0.079 | -0.4605 | No |
| 29 | ANXA4 | ANXA4 Entrez, Source | annexin A4 | 11026 | -0.113 | -0.5175 | No |
| 30 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 11608 | -0.144 | -0.5473 | No |
| 31 | CLU | CLU Entrez, Source | clusterin | 11779 | -0.155 | -0.5452 | No |
| 32 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 12163 | -0.188 | -0.5559 | Yes |
| 33 | CSRP2 | CSRP2 Entrez, Source | cysteine and glycine-rich protein 2 | 12431 | -0.219 | -0.5549 | Yes |
| 34 | IL18 | IL18 Entrez, Source | interleukin 18 (interferon-gamma-inducing factor) | 12497 | -0.228 | -0.5378 | Yes |
| 35 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 12723 | -0.270 | -0.5288 | Yes |
| 36 | CLIC4 | CLIC4 Entrez, Source | chloride intracellular channel 4 | 12732 | -0.272 | -0.5033 | Yes |
| 37 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 13198 | -0.561 | -0.4842 | Yes |
| 38 | GPNMB | GPNMB Entrez, Source | glycoprotein (transmembrane) nmb | 13207 | -0.576 | -0.4295 | Yes |
| 39 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 13233 | -0.633 | -0.3705 | Yes |
| 40 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 13309 | -0.997 | -0.2802 | Yes |
| 41 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13327 | -1.146 | -0.1713 | Yes |
| 42 | CPE | CPE Entrez, Source | carboxypeptidase E | 13342 | -1.792 | 0.0000 | Yes |
