Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | FATTY_ACID_METABOLIC_PROCESS |
| Enrichment Score (ES) | 0.6835602 |
| Normalized Enrichment Score (NES) | 2.1840672 |
| Nominal p-value | 0.0 |
| FDR q-value | 8.668304E-5 |
| FWER p-Value | 0.0040 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GLYAT | GLYAT Entrez, Source | glycine-N-acyltransferase | 10 | 1.121 | 0.1190 | Yes |
| 2 | FADS2 | FADS2 Entrez, Source | fatty acid desaturase 2 | 98 | 0.617 | 0.1783 | Yes |
| 3 | HACL1 | HACL1 Entrez, Source | 2-hydroxyacyl-CoA lyase 1 | 177 | 0.496 | 0.2254 | Yes |
| 4 | ACOT12 | ACOT12 Entrez, Source | acyl-CoA thioesterase 12 | 212 | 0.461 | 0.2721 | Yes |
| 5 | ACOT2 | ACOT2 Entrez, Source | acyl-CoA thioesterase 2 | 231 | 0.450 | 0.3188 | Yes |
| 6 | ECHS1 | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 260 | 0.427 | 0.3623 | Yes |
| 7 | SC4MOL | SC4MOL Entrez, Source | sterol-C4-methyl oxidase-like | 284 | 0.409 | 0.4043 | Yes |
| 8 | SLC27A5 | SLC27A5 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 5 | 392 | 0.341 | 0.4327 | Yes |
| 9 | FADS1 | FADS1 Entrez, Source | fatty acid desaturase 1 | 401 | 0.338 | 0.4682 | Yes |
| 10 | CYP4F2 | CYP4F2 Entrez, Source | cytochrome P450, family 4, subfamily F, polypeptide 2 | 403 | 0.337 | 0.5041 | Yes |
| 11 | FAAH | FAAH Entrez, Source | fatty acid amide hydrolase | 501 | 0.299 | 0.5288 | Yes |
| 12 | ACADVL | ACADVL Entrez, Source | acyl-Coenzyme A dehydrogenase, very long chain | 537 | 0.288 | 0.5569 | Yes |
| 13 | MLYCD | MLYCD Entrez, Source | malonyl-CoA decarboxylase | 584 | 0.271 | 0.5824 | Yes |
| 14 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 732 | 0.231 | 0.5961 | Yes |
| 15 | ALDH5A1 | ALDH5A1 Entrez, Source | aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 870 | 0.211 | 0.6083 | Yes |
| 16 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 950 | 0.200 | 0.6238 | Yes |
| 17 | ACADSB | ACADSB Entrez, Source | acyl-Coenzyme A dehydrogenase, short/branched chain | 1158 | 0.175 | 0.6269 | Yes |
| 18 | HAO2 | HAO2 Entrez, Source | hydroxyacid oxidase 2 (long chain) | 1180 | 0.172 | 0.6437 | Yes |
| 19 | CPT1B | CPT1B Entrez, Source | carnitine palmitoyltransferase 1B (muscle) | 1278 | 0.165 | 0.6541 | Yes |
| 20 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 1296 | 0.164 | 0.6704 | Yes |
| 21 | PECI | PECI Entrez, Source | peroxisomal D3,D2-enoyl-CoA isomerase | 1680 | 0.138 | 0.6563 | Yes |
| 22 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 1747 | 0.134 | 0.6657 | Yes |
| 23 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 1770 | 0.133 | 0.6782 | Yes |
| 24 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 1920 | 0.125 | 0.6804 | Yes |
| 25 | PTGES | PTGES Entrez, Source | prostaglandin E synthase | 2249 | 0.113 | 0.6678 | Yes |
| 26 | ECH1 | ECH1 Entrez, Source | enoyl Coenzyme A hydratase 1, peroxisomal | 2294 | 0.111 | 0.6763 | Yes |
| 27 | MIF | MIF Entrez, Source | macrophage migration inhibitory factor (glycosylation-inhibiting factor) | 2352 | 0.108 | 0.6836 | Yes |
| 28 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 2832 | 0.090 | 0.6572 | No |
| 29 | ADIPOR2 | ADIPOR2 Entrez, Source | adiponectin receptor 2 | 3114 | 0.081 | 0.6447 | No |
| 30 | PPARD | PPARD Entrez, Source | peroxisome proliferative activated receptor, delta | 3231 | 0.078 | 0.6443 | No |
| 31 | ACOX3 | ACOX3 Entrez, Source | acyl-Coenzyme A oxidase 3, pristanoyl | 4291 | 0.053 | 0.5703 | No |
| 32 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 4310 | 0.053 | 0.5746 | No |
| 33 | ABCD2 | ABCD2 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 2 | 4613 | 0.046 | 0.5568 | No |
| 34 | PTGDS | PTGDS Entrez, Source | prostaglandin D2 synthase 21kDa (brain) | 5784 | 0.022 | 0.4712 | No |
| 35 | PTGS1 | PTGS1 Entrez, Source | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | 6103 | 0.016 | 0.4490 | No |
| 36 | ADIPOR1 | ADIPOR1 Entrez, Source | adiponectin receptor 1 | 7451 | -0.011 | 0.3490 | No |
| 37 | GNPAT | GNPAT Entrez, Source | glyceronephosphate O-acyltransferase | 7996 | -0.023 | 0.3106 | No |
| 38 | DEGS1 | DEGS1 Entrez, Source | degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) | 10024 | -0.075 | 0.1662 | No |
| 39 | LYPLA3 | LYPLA3 Entrez, Source | lysophospholipase 3 (lysosomal phospholipase A2) | 10907 | -0.107 | 0.1113 | No |
| 40 | CD74 | CD74 Entrez, Source | CD74 molecule, major histocompatibility complex, class II invariant chain | 10944 | -0.109 | 0.1203 | No |
| 41 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 11523 | -0.139 | 0.0916 | No |
| 42 | LTA4H | LTA4H Entrez, Source | leukotriene A4 hydrolase | 12246 | -0.198 | 0.0585 | No |
| 43 | CROT | CROT Entrez, Source | carnitine O-octanoyltransferase | 12469 | -0.223 | 0.0656 | No |
