Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_single_gel_8d.class.cls
#double_gel_8d_versus_single_gel_8d_repos
Phenotypeclass.cls#double_gel_8d_versus_single_gel_8d_repos
Upregulated in classdouble_gel_8d
GeneSetFLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN
Enrichment Score (ES)0.42729113
Normalized Enrichment Score (NES)1.8577511
Nominal p-value0.0
FDR q-value0.008082366
FWER p-Value0.649
Table: GSEA Results Summary



Fig 1: Enrichment plot: FLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CYP17A1CYP17A1
Entrez,  Source
cytochrome P450, family 17, subfamily A, polypeptide 111.4750.0221Yes
2FABP1FABP1
Entrez,  Source
fatty acid binding protein 1, liver81.2050.0398Yes
3GLYATGLYAT
Entrez,  Source
glycine-N-acyltransferase101.1210.0566Yes
4BBOX1BBOX1
Entrez,  Source
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1160.9330.0702Yes
5G6PCG6PC
Entrez,  Source
glucose-6-phosphatase, catalytic subunit210.8930.0834Yes
6EHHADHEHHADH
Entrez,  Source
enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase240.8640.0962Yes
7PLGPLG
Entrez,  Source
plasminogen440.7730.1064Yes
8GOT1GOT1
Entrez,  Source
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)560.7310.1165Yes
9FBP1FBP1
Entrez,  Source
fructose-1,6-bisphosphatase 1660.7020.1264Yes
10PCPC
Entrez,  Source
pyruvate carboxylase790.6520.1353Yes
11SLC17A1SLC17A1
Entrez,  Source
solute carrier family 17 (sodium phosphate), member 11070.6060.1423Yes
12ABP1ABP1
Entrez,  Source
amiloride binding protein 1 (amine oxidase (copper-containing))1090.6060.1514Yes
13AZGP1AZGP1
Entrez,  Source
alpha-2-glycoprotein 1, zinc1250.5750.1589Yes
14USP2USP2
Entrez,  Source
ubiquitin specific peptidase 21340.5570.1666Yes
15BHMTBHMT
Entrez,  Source
betaine-homocysteine methyltransferase1400.5500.1745Yes
16CTHCTH
Entrez,  Source
cystathionase (cystathionine gamma-lyase)1480.5350.1820Yes
17APOMAPOM
Entrez,  Source
apolipoprotein M1560.5270.1894Yes
18PCK1PCK1
Entrez,  Source
phosphoenolpyruvate carboxykinase 1 (soluble)1670.5050.1963Yes
19HPNHPN
Entrez,  Source
hepsin (transmembrane protease, serine 1)1980.4780.2011Yes
20EPHX2EPHX2
Entrez,  Source
epoxide hydrolase 2, cytoplasmic2160.4600.2068Yes
21AK3L1AK3L1
Entrez,  Source
adenylate kinase 3-like 12320.4500.2124Yes
22AFMAFM
Entrez,  Source
afamin2380.4440.2187Yes
23DEFB1DEFB1
Entrez,  Source
defensin, beta 12420.4410.2251Yes
24DPYSDPYS
Entrez,  Source
dihydropyrimidinase2530.4320.2308Yes
25ECHS1ECHS1
Entrez,  Source
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial2600.4270.2368Yes
26BCKDHBBCKDHB
Entrez,  Source
branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease)2710.4190.2423Yes
27FAHFAH
Entrez,  Source
fumarylacetoacetate hydrolase (fumarylacetoacetase)2770.4160.2482Yes
28SC4MOLSC4MOL
Entrez,  Source
sterol-C4-methyl oxidase-like2840.4090.2539Yes
29KHKKHK
Entrez,  Source
ketohexokinase (fructokinase)2850.4070.2600Yes
30HMGCLHMGCL
Entrez,  Source
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria)3440.3710.2611Yes
31RBP4RBP4
Entrez,  Source
retinol binding protein 4, plasma3510.3610.2661Yes
32BNIP3BNIP3
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 33560.3600.2712Yes
33PRODH2PRODH2
Entrez,  Source
proline dehydrogenase (oxidase) 23650.3560.2759Yes
34GBE1GBE1
Entrez,  Source
glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV)3680.3550.2811Yes
35ACAA2ACAA2
Entrez,  Source
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)3740.3530.2860Yes
36IGFBP2IGFBP2
Entrez,  Source
insulin-like growth factor binding protein 2, 36kDa3780.3520.2911Yes
37ENPEPENPEP
Entrez,  Source
glutamyl aminopeptidase (aminopeptidase A)3880.3450.2956Yes
38CYP4F2CYP4F2
Entrez,  Source
cytochrome P450, family 4, subfamily F, polypeptide 24030.3370.2996Yes
39PAHPAH
Entrez,  Source
phenylalanine hydroxylase4110.3360.3041Yes
40ACOX1ACOX1
Entrez,  Source
acyl-Coenzyme A oxidase 1, palmitoyl4290.3290.3078Yes
41ACAT1ACAT1
Entrez,  Source
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)4300.3290.3127Yes
42MSH3MSH3
Entrez,  Source
mutS homolog 3 (E. coli)4440.3230.3166Yes
43ABATABAT
Entrez,  Source
4-aminobutyrate aminotransferase4500.3200.3210Yes
44IGFBP4IGFBP4
Entrez,  Source
insulin-like growth factor binding protein 44560.3170.3254Yes
45SERPINA5SERPINA5
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 54740.3110.3288Yes
46AHCYAHCY
Entrez,  Source
S-adenosylhomocysteine hydrolase4850.3090.3327Yes
47CD9CD9
Entrez,  Source
CD9 molecule5120.2950.3351Yes
48ALDH6A1ALDH6A1
Entrez,  Source
aldehyde dehydrogenase 6 family, member A15240.2920.3386Yes
49DDTDDT
Entrez,  Source
D-dopachrome tautomerase5830.2710.3383Yes
50VEGFVEGF
Entrez,  Source
vascular endothelial growth factor5850.2710.3423Yes
51ERBB3ERBB3
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)5950.2690.3456Yes
52ASS1ASS1
Entrez,  Source
argininosuccinate synthetase 15980.2670.3495Yes
53SC5DLSC5DL
Entrez,  Source
sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, fungal)-like6170.2610.3520Yes
54SCP2SCP2
Entrez,  Source
sterol carrier protein 26240.2600.3555Yes
55APOHAPOH
Entrez,  Source
apolipoprotein H (beta-2-glycoprotein I)6580.2510.3567Yes
56DCIDCI
Entrez,  Source
dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase)6600.2500.3604Yes
57BPHLBPHL
Entrez,  Source
biphenyl hydrolase-like (serine hydrolase; breast epithelial mucin-associated antigen)6640.2490.3639Yes
58ALDOBALDOB
Entrez,  Source
aldolase B, fructose-bisphosphate6660.2490.3676Yes
59SLC37A4SLC37A4
Entrez,  Source
solute carrier family 37 (glycerol-6-phosphate transporter), member 46750.2460.3707Yes
60SLC17A3SLC17A3
Entrez,  Source
solute carrier family 17 (sodium phosphate), member 36870.2410.3734Yes
61SLC13A3SLC13A3
Entrez,  Source
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 37250.2330.3741Yes
62PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha7360.2300.3768Yes
63HRSP12HRSP12
Entrez,  Source
heat-responsive protein 127370.2300.3803Yes
64PEX7PEX7
Entrez,  Source
peroxisomal biogenesis factor 77380.2300.3837Yes
65CDS1CDS1
Entrez,  Source
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 18170.2180.3810Yes
66SEPHS2SEPHS2
Entrez,  Source
selenophosphate synthetase 28360.2160.3829Yes
67PHYHPHYH
Entrez,  Source
phytanoyl-CoA 2-hydroxylase8490.2140.3852Yes
68ALDH5A1ALDH5A1
Entrez,  Source
aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase)8700.2110.3868Yes
69CATCAT
Entrez,  Source
catalase8840.2090.3890Yes
70GCHFRGCHFR
Entrez,  Source
GTP cyclohydrolase I feedback regulator9210.2040.3892Yes
71TSTTST
Entrez,  Source
thiosulfate sulfurtransferase (rhodanese)9260.2030.3920Yes
72PCBD1PCBD1
Entrez,  Source
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)9360.2020.3943Yes
73TMED5TMED5
Entrez,  Source
transmembrane emp24 protein transport domain containing 59430.2010.3969Yes
74CRYMCRYM
Entrez,  Source
crystallin, mu9450.2010.3998Yes
75SLC25A1SLC25A1
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 19460.2000.4028Yes
76SULT1C1SULT1C1
Entrez,  Source
sulfotransferase family, cytosolic, 1C, member 19640.1990.4045Yes
77ASPAASPA
Entrez,  Source
aspartoacylase (Canavan disease)10270.1890.4026Yes
78ENTPD5ENTPD5
Entrez,  Source
ectonucleoside triphosphate diphosphohydrolase 510310.1890.4052Yes
79PTPN3PTPN3
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 310600.1870.4059Yes
80COMTCOMT
Entrez,  Source
catechol-O-methyltransferase10650.1860.4084Yes
81ABCD3ABCD3
Entrez,  Source
ATP-binding cassette, sub-family D (ALD), member 310760.1840.4104Yes
82PDE8APDE8A
Entrez,  Source
phosphodiesterase 8A11030.1810.4111Yes
83DNAJB9DNAJB9
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 911330.1780.4115Yes
84GJB1GJB1
Entrez,  Source
gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked)11500.1760.4130Yes
85ACADSBACADSB
Entrez,  Source
acyl-Coenzyme A dehydrogenase, short/branched chain11580.1750.4150Yes
86NQO2NQO2
Entrez,  Source
NAD(P)H dehydrogenase, quinone 211740.1730.4165Yes
87IDH1IDH1
Entrez,  Source
isocitrate dehydrogenase 1 (NADP+), soluble11830.1720.4185Yes
88XPNPEP2XPNPEP2
Entrez,  Source
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound11850.1720.4210Yes
89HBLD2HBLD2
Entrez,  Source
HESB like domain containing 211860.1720.4236Yes
90WWP1WWP1
Entrez,  Source
WW domain containing E3 ubiquitin protein ligase 112060.1700.4247Yes
91HPDHPD
Entrez,  Source
4-hydroxyphenylpyruvate dioxygenase12520.1670.4237Yes
92PRDX3PRDX3
Entrez,  Source
peroxiredoxin 312740.1660.4246Yes
93PGM1PGM1
Entrez,  Source
phosphoglucomutase 113440.1610.4217Yes
94GPC3GPC3
Entrez,  Source
glypican 313590.1600.4230Yes
95CBR4CBR4
Entrez,  Source
carbonyl reductase 414010.1570.4222Yes
96ALDH3A2ALDH3A2
Entrez,  Source
aldehyde dehydrogenase 3 family, member A214030.1570.4245Yes
97ENPP2ENPP2
Entrez,  Source
ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin)14160.1560.4259Yes
98LGALS2LGALS2
Entrez,  Source
lectin, galactoside-binding, soluble, 2 (galectin 2)14510.1530.4256Yes
99OATOAT
Entrez,  Source
ornithine aminotransferase (gyrate atrophy)14600.1520.4273Yes
100FBXO9FBXO9
Entrez,  Source
F-box protein 915050.1490.4261No
101UGT8UGT8
Entrez,  Source
UDP glycosyltransferase 8 (UDP-galactose ceramide galactosyltransferase)15280.1470.4267No
102HADHHADH
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase16150.1420.4222No
103DLDDLD
Entrez,  Source
dihydrolipoamide dehydrogenase16280.1410.4234No
104ACY1ACY1
Entrez,  Source
aminoacylase 116310.1410.4254No
105FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES16910.1370.4229No
106MAOBMAOB
Entrez,  Source
monoamine oxidase B17120.1370.4234No
107GPSN2GPSN2
Entrez,  Source
glycoprotein, synaptic 217420.1350.4232No
108HADHBHADHB
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit17470.1340.4249No
109COX7BCOX7B
Entrez,  Source
cytochrome c oxidase subunit VIIb18490.1290.4191No
110SHMT1SHMT1
Entrez,  Source
serine hydroxymethyltransferase 1 (soluble)18920.1270.4177No
111DPP4DPP4
Entrez,  Source
dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2)19190.1250.4176No
112SLC12A3SLC12A3
Entrez,  Source
solute carrier family 12 (sodium/chloride transporters), member 319480.1240.4173No
113CLINT1CLINT1
Entrez,  Source
clathrin interactor 120160.1210.4140No
114LRPPRCLRPPRC
Entrez,  Source
leucine-rich PPR-motif containing20300.1210.4148No
115KLKL
Entrez,  Source
klotho20840.1180.4125No
116RRAGARRAGA
Entrez,  Source
Ras-related GTP binding A20980.1180.4133No
117SLC22A2SLC22A2
Entrez,  Source
solute carrier family 22 (organic cation transporter), member 221770.1150.4090No
118CRYAACRYAA
Entrez,  Source
crystallin, alpha A21880.1150.4100No
119IGFBP5IGFBP5
Entrez,  Source
insulin-like growth factor binding protein 522220.1140.4091No
120SLC31A1SLC31A1
Entrez,  Source
solute carrier family 31 (copper transporters), member 122370.1130.4097No
121SLC4A4SLC4A4
Entrez,  Source
solute carrier family 4, sodium bicarbonate cotransporter, member 422860.1110.4077No
122ECH1ECH1
Entrez,  Source
enoyl Coenzyme A hydratase 1, peroxisomal22940.1110.4088No
123PDZK1IP1PDZK1IP1
Entrez,  Source
PDZK1 interacting protein 122990.1100.4102No
124SLC22A6SLC22A6
Entrez,  Source
solute carrier family 22 (organic anion transporter), member 623320.1090.4094No
125MDH1MDH1
Entrez,  Source
malate dehydrogenase 1, NAD (soluble)23610.1080.4088No
126ADH6ADH6
Entrez,  Source
alcohol dehydrogenase 6 (class V)24020.1070.4074No
127HIBCHHIBCH
Entrez,  Source
3-hydroxyisobutyryl-Coenzyme A hydrolase24130.1060.4082No
128CA4CA4
Entrez,  Source
carbonic anhydrase IV24450.1050.4074No
129ATP5OATP5O
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein)24500.1050.4086No
130GHITMGHITM
Entrez,  Source
growth hormone inducible transmembrane protein24660.1040.4091No
131RAB7L1RAB7L1
Entrez,  Source
RAB7, member RAS oncogene family-like 124940.1030.4085No
132CYB5ACYB5A
Entrez,  Source
cytochrome b5 type A (microsomal)26080.0990.4013No
133ETFAETFA
Entrez,  Source
electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II)26500.0980.3996No
134OGG1OGG1
Entrez,  Source
8-oxoguanine DNA glycosylase26770.0960.3991No
135HAGHHAGH
Entrez,  Source
hydroxyacylglutathione hydrolase27380.0940.3959No
136RNF14RNF14
Entrez,  Source
ring finger protein 1427390.0940.3973No
137MAOAMAOA
Entrez,  Source
monoamine oxidase A28020.0910.3939No
138HPGDHPGD
Entrez,  Source
hydroxyprostaglandin dehydrogenase 15-(NAD)28320.0900.3930No
139NAT8NAT8
Entrez,  Source
N-acetyltransferase 8 (camello like)28620.0890.3921No
140SDHASDHA
Entrez,  Source
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)28860.0880.3917No
141RABGGTBRABGGTB
Entrez,  Source
Rab geranylgeranyltransferase, beta subunit30020.0850.3841No
142PDCD8PDCD8
Entrez,  Source
programmed cell death 8 (apoptosis-inducing factor)30030.0850.3854No
143PGRMC2PGRMC2
Entrez,  Source
progesterone receptor membrane component 230160.0840.3857No
144DSCR1DSCR1
Entrez,  Source
Down syndrome critical region gene 130350.0840.3856No
145TOMM70ATOMM70A
Entrez,  Source
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)30620.0830.3848No
146PEX19PEX19
Entrez,  Source
peroxisomal biogenesis factor 1930690.0830.3856No
147DDCDDC
Entrez,  Source
dopa decarboxylase (aromatic L-amino acid decarboxylase)31300.0810.3822No
148CLTBCLTB
Entrez,  Source
clathrin, light chain (Lcb)31510.0800.3819No
149GSTA2GSTA2
Entrez,  Source
glutathione S-transferase A231730.0790.3815No
150ESRRGESRRG
Entrez,  Source
estrogen-related receptor gamma32220.0780.3789No
151HSPE1HSPE1
Entrez,  Source
heat shock 10kDa protein 1 (chaperonin 10)32270.0780.3798No
152AKR7A2AKR7A2
Entrez,  Source
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)32780.0770.3771No
153FGF9FGF9
Entrez,  Source
fibroblast growth factor 9 (glia-activating factor)32790.0770.3783No
154PDZK1PDZK1
Entrez,  Source
PDZ domain containing 133330.0750.3753No
155KCNJ15KCNJ15
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 1533410.0750.3759No
156APLP2APLP2
Entrez,  Source
amyloid beta (A4) precursor-like protein 233890.0740.3734No
157ACO1ACO1
Entrez,  Source
aconitase 1, soluble34290.0730.3715No
158SLC7A8SLC7A8
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 834360.0730.3721No
159CDC42BPACDC42BPA
Entrez,  Source
CDC42 binding protein kinase alpha (DMPK-like)35120.0710.3674No
160PEX3PEX3
Entrez,  Source
peroxisomal biogenesis factor 335260.0700.3675No
161PGK1PGK1
Entrez,  Source
phosphoglycerate kinase 135660.0690.3655No
162MINPP1MINPP1
Entrez,  Source
multiple inositol polyphosphate histidine phosphatase, 135690.0690.3664No
163SLC26A4SLC26A4
Entrez,  Source
solute carrier family 26, member 435760.0690.3670No
164PPM1BPPM1B
Entrez,  Source
protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform36000.0690.3662No
165GATMGATM
Entrez,  Source
glycine amidinotransferase (L-arginine:glycine amidinotransferase)36910.0670.3603No
166ATP5JATP5J
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F637090.0660.3600No
167QPRTQPRT
Entrez,  Source
quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase (carboxylating))37390.0650.3587No
168TSPYL4TSPYL4
Entrez,  Source
TSPY-like 437400.0650.3597No
169TEGTTEGT
Entrez,  Source
testis enhanced gene transcript (BAX inhibitor 1)37650.0650.3588No
170SLC7A7SLC7A7
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 737740.0650.3592No
171HNMTHNMT
Entrez,  Source
histamine N-methyltransferase37890.0640.3591No
172PIK3R1PIK3R1
Entrez,  Source
phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)38760.0620.3534No
173IMPA2IMPA2
Entrez,  Source
inositol(myo)-1(or 4)-monophosphatase 238870.0620.3536No
174ATP5A1ATP5A1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle38950.0620.3540No
175SDHCSDHC
Entrez,  Source
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa38980.0620.3547No
176PHBPHB
Entrez,  Source
prohibitin39830.0600.3492No
177PHKBPHKB
Entrez,  Source
phosphorylase kinase, beta40160.0590.3476No
178UQCRFS1UQCRFS1
Entrez,  Source
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 140240.0590.3480No
179IGF1RIGF1R
Entrez,  Source
insulin-like growth factor 1 receptor41050.0570.3426No
180UQCRC2UQCRC2
Entrez,  Source
ubiquinol-cytochrome c reductase core protein II41410.0560.3408No
181ACADMACADM
Entrez,  Source
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain43100.0530.3287No
182ACO2ACO2
Entrez,  Source
aconitase 2, mitochondrial43530.0520.3262No
183CAP2CAP2
Entrez,  Source
CAP, adenylate cyclase-associated protein, 2 (yeast)44330.0500.3209No
184CREB3L2CREB3L2
Entrez,  Source
cAMP responsive element binding protein 3-like 244570.0490.3198No
185SERPINI1SERPINI1
Entrez,  Source
serpin peptidase inhibitor, clade I (neuroserpin), member 145330.0480.3148No
186QDPRQDPR
Entrez,  Source
quinoid dihydropteridine reductase46650.0450.3054No
187SLC34A1SLC34A1
Entrez,  Source
solute carrier family 34 (sodium phosphate), member 146900.0440.3042No
188ACSM3ACSM3
Entrez,  Source
acyl-CoA synthetase medium-chain family member 347860.0420.2975No
189UQCRC1UQCRC1
Entrez,  Source
ubiquinol-cytochrome c reductase core protein I48610.0410.2924No
190CGRRF1CGRRF1
Entrez,  Source
cell growth regulator with ring finger domain 148930.0400.2906No
191FPGTFPGT
Entrez,  Source
fucose-1-phosphate guanylyltransferase49710.0380.2853No
192PEX11BPEX11B
Entrez,  Source
peroxisomal biogenesis factor 11B50210.0380.2821No
193DZIP1DZIP1
Entrez,  Source
DAZ interacting protein 151220.0360.2749No
194EFHA1EFHA1
Entrez,  Source
EF-hand domain family, member A151310.0350.2748No
195MYH11MYH11
Entrez,  Source
myosin, heavy chain 11, smooth muscle53150.0320.2612No
196CYCSCYCS
Entrez,  Source
cytochrome c, somatic53200.0320.2614No
197NDUFS1NDUFS1
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)53950.0300.2561No
198SORDSORD
Entrez,  Source
sorbitol dehydrogenase54560.0290.2519No
199CDH1CDH1
Entrez,  Source
cadherin 1, type 1, E-cadherin (epithelial)55580.0260.2445No
200TNFRSF11BTNFRSF11B
Entrez,  Source
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)55770.0260.2435No
201RFKRFK
Entrez,  Source
riboflavin kinase56250.0250.2403No
202PTGER3PTGER3
Entrez,  Source
prostaglandin E receptor 3 (subtype EP3)56260.0250.2407No
203MAFMAF
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)56340.0250.2405No
204BEXL1BEXL1
Entrez,  Source
brain expressed X-linked-like 156780.0240.2376No
205CALB1CALB1
Entrez,  Source
calbindin 1, 28kDa58990.0200.2209No
206AKR7A3AKR7A3
Entrez,  Source
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)59060.0200.2208No
207CLDN8CLDN8
Entrez,  Source
claudin 859100.0200.2208No
208ANK3ANK3
Entrez,  Source
ankyrin 3, node of Ranvier (ankyrin G)60840.0170.2078No
209HSD11B2HSD11B2
Entrez,  Source
hydroxysteroid (11-beta) dehydrogenase 261110.0160.2060No
210ANPEPANPEP
Entrez,  Source
alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150)62550.0130.1952No
211ALDH2ALDH2
Entrez,  Source
aldehyde dehydrogenase 2 family (mitochondrial)62790.0120.1936No
212MRPS18BMRPS18B
Entrez,  Source
mitochondrial ribosomal protein S18B62920.0120.1929No
213STRAPSTRAP
Entrez,  Source
serine/threonine kinase receptor associated protein63870.0100.1858No
214PMPCBPMPCB
Entrez,  Source
peptidase (mitochondrial processing) beta64060.0090.1845No
215VDAC1VDAC1
Entrez,  Source
voltage-dependent anion channel 164210.0090.1836No
216STCHSTCH
Entrez,  Source
stress 70 protein chaperone, microsome-associated, 60kDa64240.0090.1836No
217AQP3AQP3
Entrez,  Source
aquaporin 3 (Gill blood group)64620.0090.1808No
218NDUFS4NDUFS4
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)64770.0080.1799No
219GPR116GPR116
Entrez,  Source
G protein-coupled receptor 11664880.0080.1792No
220LRP2LRP2
Entrez,  Source
low density lipoprotein-related protein 265080.0080.1779No
221NDUFA5NDUFA5
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa65530.0070.1746No
222C1QBPC1QBP
Entrez,  Source
complement component 1, q subcomponent binding protein66970.0040.1637No
223MFAP3LMFAP3L
Entrez,  Source
microfibrillar-associated protein 3-like67160.0040.1623No
224ALBALB
Entrez,  Source
albumin67390.0040.1607No
225PFN2PFN2
Entrez,  Source
profilin 267450.0030.1604No
226HSPD1HSPD1
Entrez,  Source
heat shock 60kDa protein 1 (chaperonin)67720.0030.1584No
227COX6A1COX6A1
Entrez,  Source
cytochrome c oxidase subunit VIa polypeptide 168670.0010.1512No
228IMMTIMMT
Entrez,  Source
inner membrane protein, mitochondrial (mitofilin)68760.0010.1506No
229NEK4NEK4
Entrez,  Source
NIMA (never in mitosis gene a)-related kinase 46956-0.0010.1445No
230TOMM20TOMM20
Entrez,  Source
translocase of outer mitochondrial membrane 20 homolog (yeast)7072-0.0040.1357No
231RAB1ARAB1A
Entrez,  Source
RAB1A, member RAS oncogene family7239-0.0070.1230No
232AQP1AQP1
Entrez,  Source
aquaporin 1 (Colton blood group)7326-0.0090.1165No
233DNM1LDNM1L
Entrez,  Source
dynamin 1-like7354-0.0090.1146No
234COL4A4COL4A4
Entrez,  Source
collagen, type IV, alpha 47382-0.0100.1127No
235CRYZCRYZ
Entrez,  Source
crystallin, zeta (quinone reductase)7414-0.0110.1104No
236TRIM2TRIM2
Entrez,  Source
tripartite motif-containing 27437-0.0110.1089No
237PTHR1PTHR1
Entrez,  Source
parathyroid hormone receptor 17539-0.0130.1013No
238SHANK2SHANK2
Entrez,  Source
SH3 and multiple ankyrin repeat domains 27570-0.0140.0992No
239TMED10TMED10
Entrez,  Source
transmembrane emp24-like trafficking protein 10 (yeast)7641-0.0150.0941No
240FMO1FMO1
Entrez,  Source
flavin containing monooxygenase 17782-0.0180.0836No
241SCAMP1SCAMP1
Entrez,  Source
secretory carrier membrane protein 17837-0.0190.0797No
242SOD1SOD1
Entrez,  Source
superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))7856-0.0200.0786No
243ACPPACPP
Entrez,  Source
acid phosphatase, prostate7892-0.0210.0762No
244NR1D2NR1D2
Entrez,  Source
nuclear receptor subfamily 1, group D, member 27919-0.0210.0745No
245SLC1A1SLC1A1
Entrez,  Source
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 18024-0.0240.0669No
246NARSNARS
Entrez,  Source
asparaginyl-tRNA synthetase8055-0.0250.0650No
247COPS2COPS2
Entrez,  Source
COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)8185-0.0270.0554No
248PGRMC1PGRMC1
Entrez,  Source
progesterone receptor membrane component 18187-0.0270.0558No
249KDRKDR
Entrez,  Source
kinase insert domain receptor (a type III receptor tyrosine kinase)8279-0.0290.0492No
250PJA2PJA2
Entrez,  Source
praja 2, RING-H2 motif containing8319-0.0300.0466No
251VDAC2VDAC2
Entrez,  Source
voltage-dependent anion channel 28404-0.0320.0407No
252CTSLCTSL
Entrez,  Source
cathepsin L8440-0.0330.0385No
253ST13ST13
Entrez,  Source
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)8530-0.0350.0321No
254G3BPG3BP
Entrez,  Source
-8786-0.0400.0131No
255ZMYND11ZMYND11
Entrez,  Source
zinc finger, MYND domain containing 118813-0.0410.0117No
256CYB5R3CYB5R3
Entrez,  Source
cytochrome b5 reductase 38840-0.0420.0104No
257EBNA1BP2EBNA1BP2
Entrez,  Source
EBNA1 binding protein 28885-0.0430.0076No
258COPS5COPS5
Entrez,  Source
COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)8889-0.0430.0080No
259YWHAEYWHAE
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide8995-0.0460.0006No
260SERBP1SERBP1
Entrez,  Source
SERPINE1 mRNA binding protein 19117-0.049-0.0079No
261PEBP1PEBP1
Entrez,  Source
phosphatidylethanolamine binding protein 19172-0.051-0.0113No
262RAB2RAB2
Entrez,  Source
RAB2, member RAS oncogene family9370-0.056-0.0257No
263GRB14GRB14
Entrez,  Source
growth factor receptor-bound protein 149431-0.058-0.0294No
264ANXA7ANXA7
Entrez,  Source
annexin A79552-0.061-0.0377No
265TACSTD1TACSTD1
Entrez,  Source
tumor-associated calcium signal transducer 19570-0.062-0.0381No
266ATP2A2ATP2A2
Entrez,  Source
ATPase, Ca++ transporting, cardiac muscle, slow twitch 29620-0.063-0.0409No
267PPP2R1APPP2R1A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform9656-0.064-0.0427No
268SDC1SDC1
Entrez,  Source
syndecan 19762-0.067-0.0497No
269CFDP1CFDP1
Entrez,  Source
craniofacial development protein 19791-0.068-0.0509No
270SERINC1SERINC1
Entrez,  Source
serine incorporator 19801-0.068-0.0505No
271CTBP1CTBP1
Entrez,  Source
C-terminal binding protein 19803-0.068-0.0496No
272STRN3STRN3
Entrez,  Source
striatin, calmodulin binding protein 39894-0.071-0.0554No
273PRKAR1APRKAR1A
Entrez,  Source
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)9898-0.071-0.0546No
274LRPAP1LRPAP1
Entrez,  Source
low density lipoprotein receptor-related protein associated protein 19995-0.074-0.0609No
275ANKRD15ANKRD15
Entrez,  Source
ankyrin repeat domain 1510069-0.077-0.0653No
276TOB1TOB1
Entrez,  Source
transducer of ERBB2, 110157-0.080-0.0708No
277ADD3ADD3
Entrez,  Source
adducin 3 (gamma)10162-0.080-0.0699No
278PCBP2PCBP2
Entrez,  Source
poly(rC) binding protein 210175-0.081-0.0697No
279ANKRD46ANKRD46
Entrez,  Source
ankyrin repeat domain 4610190-0.081-0.0695No
280NR3C2NR3C2
Entrez,  Source
nuclear receptor subfamily 3, group C, member 210284-0.084-0.0754No
281HSPA8HSPA8
Entrez,  Source
heat shock 70kDa protein 810327-0.086-0.0774No
282MORF4L2MORF4L2
Entrez,  Source
mortality factor 4 like 210413-0.089-0.0826No
283USP14USP14
Entrez,  Source
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)10428-0.089-0.0823No
284PPP2CBPPP2CB
Entrez,  Source
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform10468-0.091-0.0839No
285DAB2DAB2
Entrez,  Source
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)10515-0.092-0.0861No
286CALM1CALM1
Entrez,  Source
calmodulin 1 (phosphorylase kinase, delta)10547-0.093-0.0871No
287SLC25A4SLC25A4
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 410578-0.094-0.0880No
288SELENBP1SELENBP1
Entrez,  Source
selenium binding protein 110631-0.096-0.0905No
289NCKAP1NCKAP1
Entrez,  Source
NCK-associated protein 110650-0.097-0.0905No
290CA2CA2
Entrez,  Source
carbonic anhydrase II10674-0.098-0.0908No
291MXI1MXI1
Entrez,  Source
MAX interactor 110722-0.099-0.0929No
292AKR1A1AKR1A1
Entrez,  Source
aldo-keto reductase family 1, member A1 (aldehyde reductase)10743-0.100-0.0929No
293PLS3PLS3
Entrez,  Source
plastin 3 (T isoform)10786-0.102-0.0946No
294PAFAH1B1PAFAH1B1
Entrez,  Source
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa10819-0.104-0.0955No
295FAM3CFAM3C
Entrez,  Source
family with sequence similarity 3, member C10863-0.105-0.0972No
296COPACOPA
Entrez,  Source
coatomer protein complex, subunit alpha10872-0.106-0.0963No
297PRPSAP2PRPSAP2
Entrez,  Source
phosphoribosyl pyrophosphate synthetase-associated protein 210927-0.108-0.0988No
298HDGFHDGF
Entrez,  Source
hepatoma-derived growth factor (high-mobility group protein 1-like)10997-0.112-0.1024No
299UGDHUGDH
Entrez,  Source
UDP-glucose dehydrogenase11033-0.113-0.1034No
300ITM2BITM2B
Entrez,  Source
integral membrane protein 2B11047-0.114-0.1027No
301AKAP11AKAP11
Entrez,  Source
A kinase (PRKA) anchor protein 1111090-0.116-0.1042No
302SMAD5SMAD5
Entrez,  Source
SMAD, mothers against DPP homolog 5 (Drosophila)11093-0.116-0.1026No
303DDX3XDDX3X
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked11094-0.116-0.1009No
304DAPDAP
Entrez,  Source
death-associated protein11144-0.119-0.1028No
305PRDX2PRDX2
Entrez,  Source
peroxiredoxin 211173-0.120-0.1032No
306ZNF148ZNF148
Entrez,  Source
zinc finger protein 14811301-0.126-0.1111No
307AP3D1AP3D1
Entrez,  Source
adaptor-related protein complex 3, delta 1 subunit11360-0.129-0.1136No
308RDXRDX
Entrez,  Source
radixin11397-0.131-0.1144No
309FOLH1FOLH1
Entrez,  Source
folate hydrolase (prostate-specific membrane antigen) 111469-0.135-0.1178No
310ATF2ATF2
Entrez,  Source
activating transcription factor 211597-0.143-0.1255No
311MYH10MYH10
Entrez,  Source
myosin, heavy chain 10, non-muscle11608-0.144-0.1241No
312KIF3AKIF3A
Entrez,  Source
kinesin family member 3A11743-0.152-0.1321No
313SMAD4SMAD4
Entrez,  Source
SMAD, mothers against DPP homolog 4 (Drosophila)11978-0.171-0.1475No
314ALDH9A1ALDH9A1
Entrez,  Source
aldehyde dehydrogenase 9 family, member A111983-0.171-0.1453No
315PARGPARG
Entrez,  Source
poly (ADP-ribose) glycohydrolase12022-0.175-0.1456No
316TNPO1TNPO1
Entrez,  Source
transportin 112075-0.179-0.1469No
317HTRA1HTRA1
Entrez,  Source
HtrA serine peptidase 112165-0.188-0.1509No
318SLC3A2SLC3A2
Entrez,  Source
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 212198-0.191-0.1505No
319RNASE4RNASE4
Entrez,  Source
ribonuclease, RNase A family, 412272-0.201-0.1531No
320DSTNDSTN
Entrez,  Source
destrin (actin depolymerizing factor)12275-0.202-0.1502No
321SMPDL3ASMPDL3A
Entrez,  Source
sphingomyelin phosphodiesterase, acid-like 3A12339-0.209-0.1519No
322PRNPPRNP
Entrez,  Source
prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)12376-0.212-0.1515No
323PRKCIPRKCI
Entrez,  Source
protein kinase C, iota12399-0.215-0.1500No
324ABCC2ABCC2
Entrez,  Source
ATP-binding cassette, sub-family C (CFTR/MRP), member 212438-0.220-0.1496No
325FMR1FMR1
Entrez,  Source
fragile X mental retardation 112443-0.220-0.1466No
326PTPRDPTPRD
Entrez,  Source
protein tyrosine phosphatase, receptor type, D12478-0.224-0.1458No
327CLASP2CLASP2
Entrez,  Source
cytoplasmic linker associated protein 212533-0.233-0.1465No
328PRKRAPRKRA
Entrez,  Source
protein kinase, interferon-inducible double stranded RNA dependent activator12555-0.237-0.1445No
329DSPDSP
Entrez,  Source
desmoplakin12592-0.244-0.1436No
330HSPA4HSPA4
Entrez,  Source
heat shock 70kDa protein 412608-0.247-0.1411No
331SNRPN /// SNURF12625-0.249-0.1386No
332ITGA6ITGA6
Entrez,  Source
integrin, alpha 612719-0.269-0.1417No
333CDKN1CCDKN1C
Entrez,  Source
cyclin-dependent kinase inhibitor 1C (p57, Kip2)12725-0.270-0.1380No
334CRYABCRYAB
Entrez,  Source
crystallin, alpha B12728-0.271-0.1341No
335CLIC4CLIC4
Entrez,  Source
chloride intracellular channel 412732-0.272-0.1302No
336GGHGGH
Entrez,  Source
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)12824-0.294-0.1328No
337BAMBIBAMBI
Entrez,  Source
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)12826-0.295-0.1284No
338HSPB1HSPB1
Entrez,  Source
heat shock 27kDa protein 112892-0.318-0.1287No
339WEE1WEE1
Entrez,  Source
WEE1 homolog (S. pombe)12897-0.319-0.1242No
340VAT1VAT1
Entrez,  Source
vesicle amine transport protein 1 homolog (T californica)12903-0.323-0.1197No
341HRASLS3HRASLS3
Entrez,  Source
HRAS-like suppressor 312972-0.348-0.1197No
342PODXLPODXL
Entrez,  Source
podocalyxin-like13001-0.365-0.1164No
343RGNRGN
Entrez,  Source
regucalcin (senescence marker protein-30)13038-0.386-0.1133No
344GULP1GULP1
Entrez,  Source
GULP, engulfment adaptor PTB domain containing 113058-0.404-0.1087No
345GLSGLS
Entrez,  Source
glutaminase13118-0.442-0.1066No
346PARD3PARD3
Entrez,  Source
par-3 partitioning defective 3 homolog (C. elegans)13124-0.445-0.1003No
347GPX3GPX3
Entrez,  Source
glutathione peroxidase 3 (plasma)13136-0.457-0.0943No
348ABCC4ABCC4
Entrez,  Source
ATP-binding cassette, sub-family C (CFTR/MRP), member 413157-0.491-0.0884No
349RTN4RTN4
Entrez,  Source
reticulon 413160-0.500-0.0810No
350PDLIM5PDLIM5
Entrez,  Source
PDZ and LIM domain 513173-0.513-0.0742No
351FGF1FGF1
Entrez,  Source
fibroblast growth factor 1 (acidic)13192-0.544-0.0675No
352MPDZMPDZ
Entrez,  Source
multiple PDZ domain protein13220-0.602-0.0605No
353MMEMME
Entrez,  Source
membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)13232-0.631-0.0518No
354TSC22D1TSC22D1
Entrez,  Source
TSC22 domain family, member 113246-0.674-0.0427No
355PPP2R3APPP2R3A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha13267-0.745-0.0330No
356F2RF2R
Entrez,  Source
coagulation factor II (thrombin) receptor13270-0.762-0.0217No
357NDRG1NDRG1
Entrez,  Source
N-myc downstream regulated gene 113282-0.795-0.0106No
358ARMCX2ARMCX2
Entrez,  Source
armadillo repeat containing, X-linked 213310-1.0050.0025No
Table: GSEA details [plain text format]



Fig 2: FLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: FLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN: Random ES distribution   
Gene set null distribution of ES for FLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN