Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | FLECHNER_KIDNEY_TRANSPLANT_REJECTION_PBL_UP |
| Enrichment Score (ES) | -0.55585593 |
| Normalized Enrichment Score (NES) | -1.6841122 |
| Nominal p-value | 0.007561437 |
| FDR q-value | 0.081015475 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ZFP161 | ZFP161 Entrez, Source | zinc finger protein 161 homolog (mouse) | 2364 | 0.108 | -0.1532 | No |
| 2 | CANX | CANX Entrez, Source | calnexin | 2961 | 0.086 | -0.1785 | No |
| 3 | XRCC5 | XRCC5 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa) | 2976 | 0.086 | -0.1602 | No |
| 4 | HNRPA3 | HNRPA3 Entrez, Source | heterogeneous nuclear ribonucleoprotein A3 | 3804 | 0.064 | -0.2079 | No |
| 5 | MTDH | MTDH Entrez, Source | metadherin | 4365 | 0.051 | -0.2384 | No |
| 6 | SERPINE2 | SERPINE2 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 4745 | 0.043 | -0.2572 | No |
| 7 | LITAF | LITAF Entrez, Source | lipopolysaccharide-induced TNF factor | 4957 | 0.039 | -0.2643 | No |
| 8 | PARP1 | PARP1 Entrez, Source | poly (ADP-ribose) polymerase family, member 1 | 5026 | 0.037 | -0.2609 | No |
| 9 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 5855 | 0.021 | -0.3184 | No |
| 10 | PTPN12 | PTPN12 Entrez, Source | protein tyrosine phosphatase, non-receptor type 12 | 6058 | 0.017 | -0.3297 | No |
| 11 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 6115 | 0.016 | -0.3303 | No |
| 12 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 6561 | 0.007 | -0.3622 | No |
| 13 | ARHGEF1 | ARHGEF1 Entrez, Source | Rho guanine nucleotide exchange factor (GEF) 1 | 7096 | -0.004 | -0.4015 | No |
| 14 | ICAM2 | ICAM2 Entrez, Source | intercellular adhesion molecule 2 | 7636 | -0.015 | -0.4385 | No |
| 15 | TMED10 | TMED10 Entrez, Source | transmembrane emp24-like trafficking protein 10 (yeast) | 7641 | -0.015 | -0.4353 | No |
| 16 | NFYA | NFYA Entrez, Source | nuclear transcription factor Y, alpha | 7730 | -0.017 | -0.4381 | No |
| 17 | OTUD4 | OTUD4 Entrez, Source | OTU domain containing 4 | 8435 | -0.033 | -0.4835 | No |
| 18 | B2M | B2M Entrez, Source | beta-2-microglobulin | 8650 | -0.038 | -0.4910 | No |
| 19 | TAX1BP3 | TAX1BP3 Entrez, Source | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 8849 | -0.042 | -0.4964 | No |
| 20 | TAX1BP1 | TAX1BP1 Entrez, Source | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 9632 | -0.064 | -0.5407 | Yes |
| 21 | PSMD6 | PSMD6 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 9834 | -0.069 | -0.5402 | Yes |
| 22 | CDK7 | CDK7 Entrez, Source | cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) | 9912 | -0.072 | -0.5297 | Yes |
| 23 | SPINT2 | SPINT2 Entrez, Source | serine peptidase inhibitor, Kunitz type, 2 | 9927 | -0.073 | -0.5143 | Yes |
| 24 | CCDC131 | CCDC131 Entrez, Source | coiled-coil domain containing 131 | 10222 | -0.082 | -0.5179 | Yes |
| 25 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 10400 | -0.088 | -0.5112 | Yes |
| 26 | AGPAT1 | AGPAT1 Entrez, Source | 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) | 10638 | -0.097 | -0.5072 | Yes |
| 27 | ANXA4 | ANXA4 Entrez, Source | annexin A4 | 11026 | -0.113 | -0.5107 | Yes |
| 28 | DNPEP | DNPEP Entrez, Source | aspartyl aminopeptidase | 11066 | -0.115 | -0.4877 | Yes |
| 29 | SHOC2 | SHOC2 Entrez, Source | soc-2 suppressor of clear homolog (C. elegans) | 11458 | -0.135 | -0.4866 | Yes |
| 30 | CD47 | CD47 Entrez, Source | CD47 molecule | 11473 | -0.136 | -0.4570 | Yes |
| 31 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 11589 | -0.143 | -0.4333 | Yes |
| 32 | TXNRD1 | TXNRD1 Entrez, Source | thioredoxin reductase 1 | 11903 | -0.166 | -0.4194 | Yes |
| 33 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 12725 | -0.270 | -0.4200 | Yes |
| 34 | KNS2 | KNS2 Entrez, Source | kinesin 2 | 12768 | -0.278 | -0.3603 | Yes |
| 35 | TSC22D3 | TSC22D3 Entrez, Source | TSC22 domain family, member 3 | 13117 | -0.441 | -0.2867 | Yes |
| 36 | PDLIM5 | PDLIM5 Entrez, Source | PDZ and LIM domain 5 | 13173 | -0.513 | -0.1748 | Yes |
| 37 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13289 | -0.828 | 0.0040 | Yes |
