Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | FSH_OVARY_MCV152_UP |
| Enrichment Score (ES) | 0.5732611 |
| Normalized Enrichment Score (NES) | 1.75567 |
| Nominal p-value | 0.004032258 |
| FDR q-value | 0.020262301 |
| FWER p-Value | 0.973 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FADS2 | FADS2 Entrez, Source | fatty acid desaturase 2 | 98 | 0.617 | 0.0669 | Yes |
| 2 | IDI1 | IDI1 Entrez, Source | isopentenyl-diphosphate delta isomerase 1 | 110 | 0.603 | 0.1386 | Yes |
| 3 | CYP51A1 | CYP51A1 Entrez, Source | cytochrome P450, family 51, subfamily A, polypeptide 1 | 157 | 0.524 | 0.1982 | Yes |
| 4 | SQLE | SQLE Entrez, Source | squalene epoxidase | 188 | 0.485 | 0.2543 | Yes |
| 5 | FDFT1 | FDFT1 Entrez, Source | farnesyl-diphosphate farnesyltransferase 1 | 194 | 0.481 | 0.3118 | Yes |
| 6 | FASN | FASN Entrez, Source | fatty acid synthase | 213 | 0.460 | 0.3659 | Yes |
| 7 | TM7SF2 | TM7SF2 Entrez, Source | transmembrane 7 superfamily member 2 | 258 | 0.428 | 0.4140 | Yes |
| 8 | FDPS | FDPS Entrez, Source | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | 315 | 0.386 | 0.4562 | Yes |
| 9 | MVD | MVD Entrez, Source | mevalonate (diphospho) decarboxylase | 328 | 0.380 | 0.5010 | Yes |
| 10 | FADS1 | FADS1 Entrez, Source | fatty acid desaturase 1 | 401 | 0.338 | 0.5363 | Yes |
| 11 | HMGCR | HMGCR Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase | 434 | 0.327 | 0.5733 | Yes |
| 12 | NAB1 | NAB1 Entrez, Source | NGFI-A binding protein 1 (EGR1 binding protein 1) | 1245 | 0.167 | 0.5325 | No |
| 13 | PIR | PIR Entrez, Source | pirin (iron-binding nuclear protein) | 1602 | 0.143 | 0.5230 | No |
| 14 | GOSR1 | GOSR1 Entrez, Source | golgi SNAP receptor complex member 1 | 2439 | 0.105 | 0.4728 | No |
| 15 | ATP5I | ATP5I Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E | 3963 | 0.061 | 0.3656 | No |
| 16 | SPOP | SPOP Entrez, Source | speckle-type POZ protein | 4316 | 0.052 | 0.3455 | No |
| 17 | RBP1 | RBP1 Entrez, Source | retinol binding protein 1, cellular | 4881 | 0.040 | 0.3079 | No |
| 18 | ANK3 | ANK3 Entrez, Source | ankyrin 3, node of Ranvier (ankyrin G) | 6084 | 0.017 | 0.2196 | No |
| 19 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 6556 | 0.007 | 0.1850 | No |
| 20 | COL16A1 | COL16A1 Entrez, Source | collagen, type XVI, alpha 1 | 7444 | -0.011 | 0.1197 | No |
| 21 | EEF1A1 | EEF1A1 Entrez, Source | eukaryotic translation elongation factor 1 alpha 1 | 7913 | -0.021 | 0.0871 | No |
| 22 | SLC4A3 | SLC4A3 Entrez, Source | solute carrier family 4, anion exchanger, member 3 | 7978 | -0.023 | 0.0851 | No |
| 23 | BFSP1 | BFSP1 Entrez, Source | beaded filament structural protein 1, filensin | 8014 | -0.024 | 0.0853 | No |
| 24 | FCGRT | FCGRT Entrez, Source | Fc fragment of IgG, receptor, transporter, alpha | 8110 | -0.026 | 0.0812 | No |
| 25 | PDCD4 | PDCD4 Entrez, Source | programmed cell death 4 (neoplastic transformation inhibitor) | 8221 | -0.028 | 0.0764 | No |
| 26 | CASP1 | CASP1 Entrez, Source | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 8454 | -0.033 | 0.0629 | No |
| 27 | PSMB4 | PSMB4 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 4 | 9019 | -0.046 | 0.0261 | No |
| 28 | HIST2H2AA3 | HIST2H2AA3 Entrez, Source | histone cluster 2, H2aa3 | 9131 | -0.050 | 0.0237 | No |
| 29 | CTNNB1 | CTNNB1 Entrez, Source | catenin (cadherin-associated protein), beta 1, 88kDa | 10376 | -0.087 | -0.0592 | No |
| 30 | ZNF148 | ZNF148 Entrez, Source | zinc finger protein 148 | 11301 | -0.126 | -0.1135 | No |
| 31 | CLU | CLU Entrez, Source | clusterin | 11779 | -0.155 | -0.1307 | No |
| 32 | PSMB9 | PSMB9 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 11832 | -0.159 | -0.1154 | No |
| 33 | CASP6 | CASP6 Entrez, Source | caspase 6, apoptosis-related cysteine peptidase | 11970 | -0.171 | -0.1052 | No |
| 34 | TNPO1 | TNPO1 Entrez, Source | transportin 1 | 12075 | -0.179 | -0.0914 | No |
| 35 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 12902 | -0.323 | -0.1146 | No |
| 36 | AXL | AXL Entrez, Source | AXL receptor tyrosine kinase | 13219 | -0.601 | -0.0660 | No |
| 37 | DPYSL3 | DPYSL3 Entrez, Source | dihydropyrimidinase-like 3 | 13228 | -0.625 | 0.0086 | No |
