Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | G1PATHWAY |
| Enrichment Score (ES) | -0.6842307 |
| Normalized Enrichment Score (NES) | -1.7613034 |
| Nominal p-value | 0.01002004 |
| FDR q-value | 0.060313676 |
| FWER p-Value | 0.983 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DHFR | DHFR Entrez, Source | dihydrofolate reductase | 457 | 0.317 | 0.0419 | No |
| 2 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 2067 | 0.119 | -0.0503 | No |
| 3 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 2307 | 0.110 | -0.0418 | No |
| 4 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 3808 | 0.064 | -0.1391 | No |
| 5 | CCNE1 | CCNE1 Entrez, Source | cyclin E1 | 4056 | 0.058 | -0.1436 | No |
| 6 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4801 | 0.042 | -0.1894 | No |
| 7 | CCNA1 | CCNA1 Entrez, Source | cyclin A1 | 5345 | 0.031 | -0.2227 | No |
| 8 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 7589 | -0.014 | -0.3876 | No |
| 9 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 8782 | -0.040 | -0.4673 | No |
| 10 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 11673 | -0.148 | -0.6486 | Yes |
| 11 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 11690 | -0.149 | -0.6140 | Yes |
| 12 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 12163 | -0.188 | -0.6043 | Yes |
| 13 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 12251 | -0.199 | -0.5631 | Yes |
| 14 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 12794 | -0.284 | -0.5354 | Yes |
| 15 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 12832 | -0.296 | -0.4672 | Yes |
| 16 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 13047 | -0.395 | -0.3884 | Yes |
| 17 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 13099 | -0.425 | -0.2902 | Yes |
| 18 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13162 | -0.500 | -0.1747 | Yes |
| 19 | TGFB3 | TGFB3 Entrez, Source | transforming growth factor, beta 3 | 13277 | -0.783 | 0.0049 | Yes |
