Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | G1_TO_S_CELL_CYCLE_REACTOME |
| Enrichment Score (ES) | -0.64180857 |
| Normalized Enrichment Score (NES) | -2.0035493 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.008116647 |
| FWER p-Value | 0.111 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CREB3L3 | CREB3L3 Entrez, Source | cAMP responsive element binding protein 3-like 3 | 690 | 0.241 | -0.0190 | No |
| 2 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 2307 | 0.110 | -0.1255 | No |
| 3 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 3805 | 0.064 | -0.2294 | No |
| 4 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 3808 | 0.064 | -0.2208 | No |
| 5 | CCNE1 | CCNE1 Entrez, Source | cyclin E1 | 4056 | 0.058 | -0.2314 | No |
| 6 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4801 | 0.042 | -0.2817 | No |
| 7 | ORC2L | ORC2L Entrez, Source | origin recognition complex, subunit 2-like (yeast) | 5273 | 0.032 | -0.3126 | No |
| 8 | CCNA1 | CCNA1 Entrez, Source | cyclin A1 | 5345 | 0.031 | -0.3137 | No |
| 9 | ORC4L | ORC4L Entrez, Source | origin recognition complex, subunit 4-like (yeast) | 6443 | 0.009 | -0.3950 | No |
| 10 | CCNH | CCNH Entrez, Source | cyclin H | 7280 | -0.008 | -0.4568 | No |
| 11 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 7589 | -0.014 | -0.4780 | No |
| 12 | CCND3 | CCND3 Entrez, Source | cyclin D3 | 7859 | -0.020 | -0.4955 | No |
| 13 | CREB3L4 | CREB3L4 Entrez, Source | cAMP responsive element binding protein 3-like 4 | 8167 | -0.027 | -0.5149 | No |
| 14 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 8322 | -0.030 | -0.5224 | No |
| 15 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 8707 | -0.039 | -0.5459 | No |
| 16 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 9083 | -0.048 | -0.5675 | No |
| 17 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 9233 | -0.052 | -0.5716 | No |
| 18 | CDKN2D | CDKN2D Entrez, Source | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 9788 | -0.068 | -0.6040 | No |
| 19 | CDK7 | CDK7 Entrez, Source | cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) | 9912 | -0.072 | -0.6035 | No |
| 20 | GBA2 | GBA2 Entrez, Source | glucosidase, beta (bile acid) 2 | 10142 | -0.079 | -0.6099 | No |
| 21 | CREB3L1 | CREB3L1 Entrez, Source | cAMP responsive element binding protein 3-like 1 | 10249 | -0.083 | -0.6065 | No |
| 22 | CREBL1 | CREBL1 Entrez, Source | cAMP responsive element binding protein-like 1 | 10383 | -0.088 | -0.6045 | No |
| 23 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 10651 | -0.097 | -0.6114 | No |
| 24 | MNAT1 | MNAT1 Entrez, Source | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 10832 | -0.104 | -0.6107 | No |
| 25 | CREB3 | CREB3 Entrez, Source | cAMP responsive element binding protein 3 | 11134 | -0.119 | -0.6171 | No |
| 26 | E2F5 | E2F5 Entrez, Source | E2F transcription factor 5, p130-binding | 11463 | -0.135 | -0.6234 | Yes |
| 27 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 11589 | -0.143 | -0.6133 | Yes |
| 28 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 11673 | -0.148 | -0.5994 | Yes |
| 29 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 11690 | -0.149 | -0.5802 | Yes |
| 30 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 12163 | -0.188 | -0.5901 | Yes |
| 31 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 12251 | -0.199 | -0.5695 | Yes |
| 32 | ORC3L | ORC3L Entrez, Source | origin recognition complex, subunit 3-like (yeast) | 12302 | -0.205 | -0.5453 | Yes |
| 33 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 12498 | -0.229 | -0.5288 | Yes |
| 34 | ORC6L | ORC6L Entrez, Source | origin recognition complex, subunit 6 like (yeast) | 12525 | -0.232 | -0.4991 | Yes |
| 35 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 12725 | -0.270 | -0.4772 | Yes |
| 36 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 12794 | -0.284 | -0.4435 | Yes |
| 37 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12897 | -0.319 | -0.4076 | Yes |
| 38 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 12986 | -0.357 | -0.3655 | Yes |
| 39 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12999 | -0.364 | -0.3167 | Yes |
| 40 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 13016 | -0.374 | -0.2669 | Yes |
| 41 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13028 | -0.381 | -0.2158 | Yes |
| 42 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 13099 | -0.425 | -0.1631 | Yes |
| 43 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13162 | -0.500 | -0.0996 | Yes |
| 44 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13289 | -0.828 | 0.0040 | Yes |
