Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | G2PATHWAY |
| Enrichment Score (ES) | -0.73737633 |
| Normalized Enrichment Score (NES) | -1.8018049 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.047937892 |
| FWER p-Value | 0.912 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RPS6KA1 | RPS6KA1 Entrez, Source | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 4300 | 0.053 | -0.3010 | No |
| 2 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4801 | 0.042 | -0.3214 | No |
| 3 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 9083 | -0.048 | -0.6228 | No |
| 4 | CDKN2D | CDKN2D Entrez, Source | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 9788 | -0.068 | -0.6480 | No |
| 5 | YWHAH | YWHAH Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 9794 | -0.068 | -0.6206 | No |
| 6 | CDC25B | CDC25B Entrez, Source | cell division cycle 25B | 11352 | -0.129 | -0.6846 | Yes |
| 7 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 11523 | -0.139 | -0.6406 | Yes |
| 8 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 11690 | -0.149 | -0.5919 | Yes |
| 9 | CHEK2 | CHEK2 Entrez, Source | CHK2 checkpoint homolog (S. pombe) | 12031 | -0.176 | -0.5454 | Yes |
| 10 | YWHAQ | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 12130 | -0.184 | -0.4774 | Yes |
| 11 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 12163 | -0.188 | -0.4028 | Yes |
| 12 | EP300 | EP300 Entrez, Source | E1A binding protein p300 | 12496 | -0.228 | -0.3342 | Yes |
| 13 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 12821 | -0.294 | -0.2382 | Yes |
| 14 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12897 | -0.319 | -0.1130 | Yes |
| 15 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 12986 | -0.357 | 0.0267 | Yes |
