Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | GLUTAMATE_METABOLISM |
| Enrichment Score (ES) | 0.6623235 |
| Normalized Enrichment Score (NES) | 1.7849338 |
| Nominal p-value | 0.002074689 |
| FDR q-value | 0.015742766 |
| FWER p-Value | 0.925 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 56 | 0.731 | 0.1715 | Yes |
| 2 | CPS1 | CPS1 Entrez, Source | carbamoyl-phosphate synthetase 1, mitochondrial | 91 | 0.631 | 0.3208 | Yes |
| 3 | GPT | GPT Entrez, Source | glutamic-pyruvate transaminase (alanine aminotransferase) | 137 | 0.555 | 0.4510 | Yes |
| 4 | GLS2 | GLS2 Entrez, Source | glutaminase 2 (liver, mitochondrial) | 291 | 0.403 | 0.5365 | Yes |
| 5 | ABAT | ABAT Entrez, Source | 4-aminobutyrate aminotransferase | 450 | 0.320 | 0.6017 | Yes |
| 6 | ALDH5A1 | ALDH5A1 Entrez, Source | aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 870 | 0.211 | 0.6211 | Yes |
| 7 | NADSYN1 | NADSYN1 Entrez, Source | NAD synthetase 1 | 959 | 0.199 | 0.6623 | Yes |
| 8 | GLUD1 | GLUD1 Entrez, Source | glutamate dehydrogenase 1 | 1864 | 0.128 | 0.6252 | No |
| 9 | EPRS | EPRS Entrez, Source | glutamyl-prolyl-tRNA synthetase | 2170 | 0.115 | 0.6301 | No |
| 10 | GSS | GSS Entrez, Source | glutathione synthetase | 3596 | 0.069 | 0.5397 | No |
| 11 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 5183 | 0.034 | 0.4289 | No |
| 12 | GLUL | GLUL Entrez, Source | glutamate-ammonia ligase (glutamine synthetase) | 6150 | 0.015 | 0.3601 | No |
| 13 | GCLC | GCLC Entrez, Source | glutamate-cysteine ligase, catalytic subunit | 6525 | 0.007 | 0.3338 | No |
| 14 | GFPT1 | GFPT1 Entrez, Source | glutamine-fructose-6-phosphate transaminase 1 | 6698 | 0.004 | 0.3219 | No |
| 15 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 7234 | -0.007 | 0.2834 | No |
| 16 | GCLM | GCLM Entrez, Source | glutamate-cysteine ligase, modifier subunit | 8939 | -0.045 | 0.1662 | No |
| 17 | GAD2 | GAD2 Entrez, Source | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 9551 | -0.061 | 0.1350 | No |
| 18 | PPAT | PPAT Entrez, Source | phosphoribosyl pyrophosphate amidotransferase | 10398 | -0.088 | 0.0927 | No |
| 19 | GMPS | GMPS Entrez, Source | guanine monphosphate synthetase | 10477 | -0.091 | 0.1087 | No |
| 20 | GLS | GLS Entrez, Source | glutaminase | 13118 | -0.442 | 0.0168 | No |
