Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | HADDAD_CD45CD7_PLUS_VS_MINUS_DN |
| Enrichment Score (ES) | -0.5004797 |
| Normalized Enrichment Score (NES) | -1.6159022 |
| Nominal p-value | 0.0055555557 |
| FDR q-value | 0.11101249 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GRK5 | GRK5 Entrez, Source | G protein-coupled receptor kinase 5 | 176 | 0.496 | 0.0317 | No |
| 2 | PDE4B | PDE4B Entrez, Source | phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) | 367 | 0.356 | 0.0497 | No |
| 3 | CHN2 | CHN2 Entrez, Source | chimerin (chimaerin) 2 | 376 | 0.352 | 0.0810 | No |
| 4 | INPP4B | INPP4B Entrez, Source | inositol polyphosphate-4-phosphatase, type II, 105kDa | 463 | 0.314 | 0.1030 | No |
| 5 | FOXO1A | FOXO1A Entrez, Source | forkhead box O1A (rhabdomyosarcoma) | 596 | 0.268 | 0.1174 | No |
| 6 | HSPA5 | HSPA5 Entrez, Source | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 1061 | 0.186 | 0.0993 | No |
| 7 | F2RL1 | F2RL1 Entrez, Source | coagulation factor II (thrombin) receptor-like 1 | 1102 | 0.181 | 0.1128 | No |
| 8 | PRG2 | PRG2 Entrez, Source | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 1878 | 0.127 | 0.0660 | No |
| 9 | CFH | CFH Entrez, Source | complement factor H | 2176 | 0.115 | 0.0541 | No |
| 10 | HMGA2 | HMGA2 Entrez, Source | high mobility group AT-hook 2 | 2267 | 0.112 | 0.0574 | No |
| 11 | ARG2 | ARG2 Entrez, Source | arginase, type II | 3449 | 0.072 | -0.0249 | No |
| 12 | GP1BB /// SEPT5 | 3618 | 0.068 | -0.0314 | No | ||
| 13 | CACNB2 | CACNB2 Entrez, Source | calcium channel, voltage-dependent, beta 2 subunit | 3644 | 0.068 | -0.0271 | No |
| 14 | DLK1 | DLK1 Entrez, Source | delta-like 1 homolog (Drosophila) | 4057 | 0.058 | -0.0528 | No |
| 15 | CRHBP | CRHBP Entrez, Source | corticotropin releasing hormone binding protein | 4478 | 0.049 | -0.0800 | No |
| 16 | SERPINI1 | SERPINI1 Entrez, Source | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 4533 | 0.048 | -0.0798 | No |
| 17 | PDZD2 | PDZD2 Entrez, Source | PDZ domain containing 2 | 4758 | 0.043 | -0.0928 | No |
| 18 | COL5A1 | COL5A1 Entrez, Source | collagen, type V, alpha 1 | 5666 | 0.024 | -0.1588 | No |
| 19 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 5670 | 0.024 | -0.1569 | No |
| 20 | ANK3 | ANK3 Entrez, Source | ankyrin 3, node of Ranvier (ankyrin G) | 6084 | 0.017 | -0.1864 | No |
| 21 | STCH | STCH Entrez, Source | stress 70 protein chaperone, microsome-associated, 60kDa | 6424 | 0.009 | -0.2111 | No |
| 22 | HTR1F | HTR1F Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 1F | 7630 | -0.015 | -0.3004 | No |
| 23 | PLCB4 | PLCB4 Entrez, Source | phospholipase C, beta 4 | 7829 | -0.019 | -0.3136 | No |
| 24 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 9441 | -0.058 | -0.4295 | No |
| 25 | MLLT3 | MLLT3 Entrez, Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 9964 | -0.074 | -0.4621 | No |
| 26 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 9992 | -0.074 | -0.4574 | No |
| 27 | HLF | HLF Entrez, Source | hepatic leukemia factor | 9998 | -0.075 | -0.4511 | No |
| 28 | NPR3 | NPR3 Entrez, Source | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | 10036 | -0.076 | -0.4470 | No |
| 29 | KLF9 | KLF9 Entrez, Source | Kruppel-like factor 9 | 10129 | -0.079 | -0.4467 | No |
| 30 | PHLPP | PHLPP Entrez, Source | PH domain and leucine rich repeat protein phosphatase | 10612 | -0.095 | -0.4744 | No |
| 31 | RASA1 | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 10778 | -0.102 | -0.4775 | No |
| 32 | FAM3C | FAM3C Entrez, Source | family with sequence similarity 3, member C | 10863 | -0.105 | -0.4743 | No |
| 33 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 11212 | -0.122 | -0.4894 | Yes |
| 34 | ZNF148 | ZNF148 Entrez, Source | zinc finger protein 148 | 11301 | -0.126 | -0.4846 | Yes |
| 35 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 11444 | -0.134 | -0.4831 | Yes |
| 36 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 11608 | -0.144 | -0.4823 | Yes |
| 37 | BCLAF1 | BCLAF1 Entrez, Source | BCL2-associated transcription factor 1 | 11717 | -0.150 | -0.4768 | Yes |
| 38 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 11914 | -0.167 | -0.4765 | Yes |
| 39 | TJP2 | TJP2 Entrez, Source | tight junction protein 2 (zona occludens 2) | 12109 | -0.182 | -0.4746 | Yes |
| 40 | SMARCA2 | SMARCA2 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 12295 | -0.204 | -0.4700 | Yes |
| 41 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 12401 | -0.215 | -0.4585 | Yes |
| 42 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 12413 | -0.216 | -0.4397 | Yes |
| 43 | BAG3 | BAG3 Entrez, Source | BCL2-associated athanogene 3 | 12420 | -0.218 | -0.4204 | Yes |
| 44 | PTPRD | PTPRD Entrez, Source | protein tyrosine phosphatase, receptor type, D | 12478 | -0.224 | -0.4044 | Yes |
| 45 | PPM1H | PPM1H Entrez, Source | protein phosphatase 1H (PP2C domain containing) | 12517 | -0.231 | -0.3863 | Yes |
| 46 | LAPTM4B | LAPTM4B Entrez, Source | lysosomal associated protein transmembrane 4 beta | 12759 | -0.277 | -0.3794 | Yes |
| 47 | HSPB1 | HSPB1 Entrez, Source | heat shock 27kDa protein 1 | 12892 | -0.318 | -0.3605 | Yes |
| 48 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 12985 | -0.357 | -0.3351 | Yes |
| 49 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12998 | -0.364 | -0.3031 | Yes |
| 50 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13077 | -0.411 | -0.2717 | Yes |
| 51 | MPDZ | MPDZ Entrez, Source | multiple PDZ domain protein | 13220 | -0.602 | -0.2279 | Yes |
| 52 | BEX1 | BEX1 Entrez, Source | brain expressed, X-linked 1 | 13225 | -0.617 | -0.1723 | Yes |
| 53 | LOX | LOX Entrez, Source | lysyl oxidase | 13308 | -0.991 | -0.0886 | Yes |
| 54 | ARMCX2 | ARMCX2 Entrez, Source | armadillo repeat containing, X-linked 2 | 13310 | -1.005 | 0.0024 | Yes |
