Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HCC_SURVIVAL_GOOD_VS_POOR_UP |
| Enrichment Score (ES) | 0.7370231 |
| Normalized Enrichment Score (NES) | 2.7339616 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GLYAT | GLYAT Entrez, Source | glycine-N-acyltransferase | 10 | 1.121 | 0.0423 | Yes |
| 2 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 17 | 0.930 | 0.0776 | Yes |
| 3 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 21 | 0.893 | 0.1117 | Yes |
| 4 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 24 | 0.864 | 0.1448 | Yes |
| 5 | LPIN1 | LPIN1 Entrez, Source | lipin 1 | 43 | 0.774 | 0.1732 | Yes |
| 6 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 49 | 0.765 | 0.2022 | Yes |
| 7 | ACOX2 | ACOX2 Entrez, Source | acyl-Coenzyme A oxidase 2, branched chain | 60 | 0.721 | 0.2291 | Yes |
| 8 | PC | PC Entrez, Source | pyruvate carboxylase | 79 | 0.652 | 0.2529 | Yes |
| 9 | INSIG1 | INSIG1 Entrez, Source | insulin induced gene 1 | 83 | 0.642 | 0.2773 | Yes |
| 10 | ASGR1 | ASGR1 Entrez, Source | asialoglycoprotein receptor 1 | 90 | 0.632 | 0.3011 | Yes |
| 11 | CDO1 | CDO1 Entrez, Source | cysteine dioxygenase, type I | 104 | 0.612 | 0.3237 | Yes |
| 12 | MSRA | MSRA Entrez, Source | methionine sulfoxide reductase A | 135 | 0.556 | 0.3428 | Yes |
| 13 | F10 | F10 Entrez, Source | coagulation factor X | 141 | 0.550 | 0.3635 | Yes |
| 14 | SERPIND1 | SERPIND1 Entrez, Source | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | 144 | 0.544 | 0.3843 | Yes |
| 15 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 167 | 0.505 | 0.4020 | Yes |
| 16 | PKLR | PKLR Entrez, Source | pyruvate kinase, liver and RBC | 184 | 0.487 | 0.4196 | Yes |
| 17 | AQP9 | AQP9 Entrez, Source | aquaporin 9 | 197 | 0.479 | 0.4371 | Yes |
| 18 | TTPA | TTPA Entrez, Source | tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency) | 244 | 0.439 | 0.4504 | Yes |
| 19 | DPYS | DPYS Entrez, Source | dihydropyrimidinase | 253 | 0.432 | 0.4664 | Yes |
| 20 | ECHS1 | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 260 | 0.427 | 0.4824 | Yes |
| 21 | KHK | KHK Entrez, Source | ketohexokinase (fructokinase) | 285 | 0.407 | 0.4962 | Yes |
| 22 | CPT2 | CPT2 Entrez, Source | carnitine palmitoyltransferase II | 292 | 0.402 | 0.5112 | Yes |
| 23 | MASP2 | MASP2 Entrez, Source | mannan-binding lectin serine peptidase 2 | 308 | 0.392 | 0.5252 | Yes |
| 24 | SLC38A3 | SLC38A3 Entrez, Source | solute carrier family 38, member 3 | 319 | 0.384 | 0.5392 | Yes |
| 25 | SRD5A1 | SRD5A1 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 343 | 0.371 | 0.5517 | Yes |
| 26 | HADH2 | HADH2 Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase, type II | 361 | 0.357 | 0.5641 | Yes |
| 27 | SLC27A5 | SLC27A5 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 5 | 392 | 0.341 | 0.5750 | Yes |
| 28 | IL6R | IL6R Entrez, Source | interleukin 6 receptor | 398 | 0.339 | 0.5876 | Yes |
| 29 | PAH | PAH Entrez, Source | phenylalanine hydroxylase | 411 | 0.336 | 0.5996 | Yes |
| 30 | MVK | MVK Entrez, Source | mevalonate kinase (mevalonic aciduria) | 482 | 0.309 | 0.6062 | Yes |
| 31 | CES2 | CES2 Entrez, Source | carboxylesterase 2 (intestine, liver) | 489 | 0.305 | 0.6175 | Yes |
| 32 | SERPINC1 | SERPINC1 Entrez, Source | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 522 | 0.293 | 0.6263 | Yes |
| 33 | AMACR | AMACR Entrez, Source | alpha-methylacyl-CoA racemase | 533 | 0.289 | 0.6367 | Yes |
| 34 | ACF | ACF Entrez, Source | - | 567 | 0.278 | 0.6449 | Yes |
| 35 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 580 | 0.273 | 0.6545 | Yes |
| 36 | PCYT2 | PCYT2 Entrez, Source | phosphate cytidylyltransferase 2, ethanolamine | 625 | 0.260 | 0.6611 | Yes |
| 37 | SLC25A10 | SLC25A10 Entrez, Source | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 | 642 | 0.255 | 0.6698 | Yes |
| 38 | MST1 | MST1 Entrez, Source | macrophage stimulating 1 (hepatocyte growth factor-like) | 728 | 0.233 | 0.6723 | Yes |
| 39 | C4BPB | C4BPB Entrez, Source | complement component 4 binding protein, beta | 763 | 0.225 | 0.6784 | Yes |
| 40 | APOA5 | APOA5 Entrez, Source | apolipoprotein A-V | 827 | 0.217 | 0.6819 | Yes |
| 41 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 839 | 0.215 | 0.6894 | Yes |
| 42 | CPB2 | CPB2 Entrez, Source | carboxypeptidase B2 (plasma, carboxypeptidase U) | 898 | 0.208 | 0.6930 | Yes |
| 43 | FMO3 | FMO3 Entrez, Source | flavin containing monooxygenase 3 | 961 | 0.199 | 0.6960 | Yes |
| 44 | F12 | F12 Entrez, Source | coagulation factor XII (Hageman factor) | 970 | 0.198 | 0.7030 | Yes |
| 45 | SLC6A12 | SLC6A12 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 | 971 | 0.198 | 0.7106 | Yes |
| 46 | ABHD6 | ABHD6 Entrez, Source | abhydrolase domain containing 6 | 987 | 0.195 | 0.7170 | Yes |
| 47 | CES3 | CES3 Entrez, Source | carboxylesterase 3 (brain) | 1130 | 0.179 | 0.7131 | Yes |
| 48 | AR | AR Entrez, Source | androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease) | 1135 | 0.178 | 0.7196 | Yes |
| 49 | GJB1 | GJB1 Entrez, Source | gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked) | 1150 | 0.176 | 0.7253 | Yes |
| 50 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 1252 | 0.167 | 0.7241 | Yes |
| 51 | CABC1 | CABC1 Entrez, Source | chaperone, ABC1 activity of bc1 complex homolog (S. pombe) | 1268 | 0.166 | 0.7294 | Yes |
| 52 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 1296 | 0.164 | 0.7337 | Yes |
| 53 | MUCDHL | MUCDHL Entrez, Source | mucin and cadherin-like | 1335 | 0.162 | 0.7370 | Yes |
| 54 | APOC3 | APOC3 Entrez, Source | apolipoprotein C-III | 1478 | 0.151 | 0.7321 | No |
| 55 | PCCB | PCCB Entrez, Source | propionyl Coenzyme A carboxylase, beta polypeptide | 1620 | 0.142 | 0.7269 | No |
| 56 | SERPINF1 | SERPINF1 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 1787 | 0.132 | 0.7195 | No |
| 57 | STARD10 | STARD10 Entrez, Source | START domain containing 10 | 1800 | 0.131 | 0.7236 | No |
| 58 | MRPL46 | MRPL46 Entrez, Source | mitochondrial ribosomal protein L46 | 2040 | 0.120 | 0.7102 | No |
| 59 | ABCG5 | ABCG5 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 5 (sterolin 1) | 2148 | 0.116 | 0.7066 | No |
| 60 | IVD | IVD Entrez, Source | isovaleryl Coenzyme A dehydrogenase | 2248 | 0.113 | 0.7034 | No |
| 61 | EGLN2 | EGLN2 Entrez, Source | egl nine homolog 2 (C. elegans) | 2499 | 0.103 | 0.6885 | No |
| 62 | APCS | APCS Entrez, Source | amyloid P component, serum | 2625 | 0.098 | 0.6828 | No |
| 63 | SULT2A1 | SULT2A1 Entrez, Source | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 2731 | 0.094 | 0.6785 | No |
| 64 | HAGH | HAGH Entrez, Source | hydroxyacylglutathione hydrolase | 2738 | 0.094 | 0.6817 | No |
| 65 | INSR | INSR Entrez, Source | insulin receptor | 2897 | 0.088 | 0.6731 | No |
| 66 | NDUFS2 | NDUFS2 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | 2926 | 0.087 | 0.6744 | No |
| 67 | SLC2A2 | SLC2A2 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 2 | 2969 | 0.086 | 0.6745 | No |
| 68 | SERPING1 | SERPING1 Entrez, Source | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) | 3378 | 0.074 | 0.6466 | No |
| 69 | AMT | AMT Entrez, Source | aminomethyltransferase | 3875 | 0.063 | 0.6115 | No |
| 70 | CES1 | CES1 Entrez, Source | carboxylesterase 1 (monocyte/macrophage serine esterase 1) | 3984 | 0.060 | 0.6057 | No |
| 71 | CRAT | CRAT Entrez, Source | carnitine acetyltransferase | 5716 | 0.023 | 0.4759 | No |
| 72 | PPAP2A | PPAP2A Entrez, Source | phosphatidic acid phosphatase type 2A | 5751 | 0.023 | 0.4742 | No |
| 73 | MYRIP | MYRIP Entrez, Source | myosin VIIA and Rab interacting protein | 5768 | 0.022 | 0.4739 | No |
| 74 | CYP3A4 | CYP3A4 Entrez, Source | cytochrome P450, family 3, subfamily A, polypeptide 4 | 5860 | 0.021 | 0.4678 | No |
| 75 | CRYL1 | CRYL1 Entrez, Source | crystallin, lambda 1 | 5904 | 0.020 | 0.4653 | No |
| 76 | ABCG8 | ABCG8 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin 2) | 6099 | 0.016 | 0.4513 | No |
| 77 | WNT11 | WNT11 Entrez, Source | wingless-type MMTV integration site family, member 11 | 6459 | 0.009 | 0.4246 | No |
| 78 | PRDX6 | PRDX6 Entrez, Source | peroxiredoxin 6 | 6850 | 0.001 | 0.3952 | No |
| 79 | NDRG2 | NDRG2 Entrez, Source | NDRG family member 2 | 6868 | 0.001 | 0.3939 | No |
| 80 | SEC14L2 | SEC14L2 Entrez, Source | SEC14-like 2 (S. cerevisiae) | 7014 | -0.002 | 0.3831 | No |
| 81 | DCXR | DCXR Entrez, Source | dicarbonyl/L-xylulose reductase | 7272 | -0.008 | 0.3640 | No |
| 82 | ZP3 | ZP3 Entrez, Source | zona pellucida glycoprotein 3 (sperm receptor) | 7546 | -0.013 | 0.3439 | No |
| 83 | AOX1 | AOX1 Entrez, Source | aldehyde oxidase 1 | 8449 | -0.033 | 0.2771 | No |
| 84 | ITPR2 | ITPR2 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 2 | 9021 | -0.046 | 0.2357 | No |
| 85 | EPHX1 | EPHX1 Entrez, Source | epoxide hydrolase 1, microsomal (xenobiotic) | 9718 | -0.066 | 0.1857 | No |
| 86 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 10631 | -0.096 | 0.1206 | No |
| 87 | CABIN1 | CABIN1 Entrez, Source | - | 10784 | -0.102 | 0.1130 | No |
| 88 | C2 | C2 Entrez, Source | complement component 2 | 11264 | -0.125 | 0.0817 | No |
| 89 | NF1 | NF1 Entrez, Source | neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) | 11321 | -0.127 | 0.0823 | No |
| 90 | ENPP5 | ENPP5 Entrez, Source | ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative function) | 11985 | -0.172 | 0.0389 | No |
| 91 | KLK3 | KLK3 Entrez, Source | kallikrein 3, (prostate specific antigen) | 12252 | -0.199 | 0.0265 | No |
| 92 | ABCC2 | ABCC2 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 12438 | -0.220 | 0.0209 | No |
| 93 | SGPL1 | SGPL1 Entrez, Source | sphingosine-1-phosphate lyase 1 | 12559 | -0.237 | 0.0210 | No |
| 94 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 13038 | -0.386 | -0.0003 | No |
| 95 | MPDZ | MPDZ Entrez, Source | multiple PDZ domain protein | 13220 | -0.602 | 0.0092 | No |
