Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HETEROCYCLE_METABOLIC_PROCESS |
| Enrichment Score (ES) | 0.5976268 |
| Normalized Enrichment Score (NES) | 1.5537982 |
| Nominal p-value | 0.035785288 |
| FDR q-value | 0.09181492 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FTCD | FTCD Entrez, Source | formiminotransferase cyclodeaminase | 9 | 1.171 | 0.3868 | Yes |
| 2 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 524 | 0.292 | 0.4449 | Yes |
| 3 | ALDH1L1 | ALDH1L1 Entrez, Source | aldehyde dehydrogenase 1 family, member L1 | 750 | 0.228 | 0.5033 | Yes |
| 4 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 839 | 0.215 | 0.5679 | Yes |
| 5 | ALAD | ALAD Entrez, Source | aminolevulinate, delta-, dehydratase | 1424 | 0.155 | 0.5755 | Yes |
| 6 | UROS | UROS Entrez, Source | uroporphyrinogen III synthase (congenital erythropoietic porphyria) | 1842 | 0.129 | 0.5868 | Yes |
| 7 | ALAS2 | ALAS2 Entrez, Source | aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | 2203 | 0.114 | 0.5976 | Yes |
| 8 | P4HB | P4HB Entrez, Source | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide | 4100 | 0.057 | 0.4743 | No |
| 9 | BLVRA | BLVRA Entrez, Source | biliverdin reductase A | 4973 | 0.038 | 0.4215 | No |
| 10 | TSPO | TSPO Entrez, Source | translocator protein (18kDa) | 5475 | 0.028 | 0.3933 | No |
| 11 | HPRT1 | HPRT1 Entrez, Source | hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) | 7238 | -0.007 | 0.2635 | No |
| 12 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 8124 | -0.026 | 0.2057 | No |
| 13 | CPOX | CPOX Entrez, Source | coproporphyrinogen oxidase | 8432 | -0.033 | 0.1936 | No |
| 14 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 10317 | -0.085 | 0.0804 | No |
| 15 | PAICS | PAICS Entrez, Source | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 10338 | -0.086 | 0.1074 | No |
| 16 | GMPS | GMPS Entrez, Source | guanine monphosphate synthetase | 10477 | -0.091 | 0.1270 | No |
| 17 | COX15 | COX15 Entrez, Source | COX15 homolog, cytochrome c oxidase assembly protein (yeast) | 12707 | -0.266 | 0.0477 | No |
