Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | HOFFMANN_BIVSBII_BI_TABLE2 |
| Enrichment Score (ES) | -0.5638878 |
| Normalized Enrichment Score (NES) | -2.1017559 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0021528224 |
| FWER p-Value | 0.019 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 56 | 0.731 | 0.0347 | No |
| 2 | RBP4 | RBP4 Entrez, Source | retinol binding protein 4, plasma | 351 | 0.361 | 0.0318 | No |
| 3 | PSAT1 | PSAT1 Entrez, Source | phosphoserine aminotransferase 1 | 1473 | 0.151 | -0.0449 | No |
| 4 | AZIN1 | AZIN1 Entrez, Source | antizyme inhibitor 1 | 1688 | 0.138 | -0.0538 | No |
| 5 | HSPB8 | HSPB8 Entrez, Source | heat shock 22kDa protein 8 | 1968 | 0.123 | -0.0683 | No |
| 6 | RABEP1 | RABEP1 Entrez, Source | rabaptin, RAB GTPase binding effector protein 1 | 2072 | 0.118 | -0.0698 | No |
| 7 | IGH-1A | 2091 | 0.118 | -0.0648 | No | ||
| 8 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 2134 | 0.117 | -0.0618 | No |
| 9 | GPHN | GPHN Entrez, Source | gephyrin | 2447 | 0.105 | -0.0798 | No |
| 10 | FBP2 | FBP2 Entrez, Source | fructose-1,6-bisphosphatase 2 | 2767 | 0.093 | -0.0990 | No |
| 11 | IGSF10 | IGSF10 Entrez, Source | immunoglobulin superfamily, member 10 | 2849 | 0.090 | -0.1003 | No |
| 12 | PPP2CA | PPP2CA Entrez, Source | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | 3355 | 0.075 | -0.1345 | No |
| 13 | ARL1 | ARL1 Entrez, Source | ADP-ribosylation factor-like 1 | 3408 | 0.073 | -0.1345 | No |
| 14 | HES1 | HES1 Entrez, Source | hairy and enhancer of split 1, (Drosophila) | 3410 | 0.073 | -0.1307 | No |
| 15 | IER3 | IER3 Entrez, Source | immediate early response 3 | 3649 | 0.068 | -0.1451 | No |
| 16 | NELF | NELF Entrez, Source | nasal embryonic LHRH factor | 3888 | 0.062 | -0.1597 | No |
| 17 | CCNE1 | CCNE1 Entrez, Source | cyclin E1 | 4056 | 0.058 | -0.1693 | No |
| 18 | WDSUB1 | WDSUB1 Entrez, Source | WD repeat, sterile alpha motif and U-box domain containing 1 | 4214 | 0.055 | -0.1782 | No |
| 19 | NUCKS1 | NUCKS1 Entrez, Source | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 4499 | 0.048 | -0.1971 | No |
| 20 | IL4 | IL4 Entrez, Source | interleukin 4 | 4550 | 0.047 | -0.1984 | No |
| 21 | IL4R | IL4R Entrez, Source | interleukin 4 receptor | 4588 | 0.047 | -0.1987 | No |
| 22 | RAMP1 | RAMP1 Entrez, Source | receptor (calcitonin) activity modifying protein 1 | 4600 | 0.046 | -0.1970 | No |
| 23 | CD2 | CD2 Entrez, Source | CD2 molecule | 4873 | 0.040 | -0.2154 | No |
| 24 | COIL | COIL Entrez, Source | coilin | 4911 | 0.040 | -0.2161 | No |
| 25 | ATP5D | ATP5D Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit | 5013 | 0.038 | -0.2218 | No |
| 26 | MYH11 | MYH11 Entrez, Source | myosin, heavy chain 11, smooth muscle | 5315 | 0.032 | -0.2428 | No |
| 27 | WT1 | WT1 Entrez, Source | Wilms tumor 1 | 5444 | 0.029 | -0.2509 | No |
| 28 | EVL | EVL Entrez, Source | Enah/Vasp-like | 5460 | 0.029 | -0.2505 | No |
| 29 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 5560 | 0.026 | -0.2566 | No |
| 30 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 5670 | 0.024 | -0.2636 | No |
| 31 | E2F8 | E2F8 Entrez, Source | E2F transcription factor 8 | 5971 | 0.019 | -0.2852 | No |
| 32 | ANK3 | ANK3 Entrez, Source | ankyrin 3, node of Ranvier (ankyrin G) | 6084 | 0.017 | -0.2928 | No |
| 33 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 6111 | 0.016 | -0.2939 | No |
| 34 | TBXA2R | TBXA2R Entrez, Source | thromboxane A2 receptor | 6244 | 0.013 | -0.3032 | No |
| 35 | GJA4 | GJA4 Entrez, Source | gap junction protein, alpha 4, 37kDa (connexin 37) | 6569 | 0.007 | -0.3274 | No |
| 36 | CAMP | CAMP Entrez, Source | cathelicidin antimicrobial peptide | 6681 | 0.005 | -0.3355 | No |
| 37 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 6709 | 0.004 | -0.3374 | No |
| 38 | HSPD1 | HSPD1 Entrez, Source | heat shock 60kDa protein 1 (chaperonin) | 6772 | 0.003 | -0.3419 | No |
| 39 | ANP32B | ANP32B Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 6879 | 0.001 | -0.3499 | No |
| 40 | CLCN2 | CLCN2 Entrez, Source | chloride channel 2 | 6939 | -0.001 | -0.3543 | No |
| 41 | SEPP1 | SEPP1 Entrez, Source | selenoprotein P, plasma, 1 | 7281 | -0.008 | -0.3797 | No |
| 42 | CHAF1B | CHAF1B Entrez, Source | chromatin assembly factor 1, subunit B (p60) | 7873 | -0.020 | -0.4233 | No |
| 43 | FLIIH | 7969 | -0.023 | -0.4292 | No | ||
| 44 | PPIA | PPIA Entrez, Source | peptidylprolyl isomerase A (cyclophilin A) | 8000 | -0.023 | -0.4302 | No |
| 45 | RPL10 | RPL10 Entrez, Source | ribosomal protein L10 | 8132 | -0.026 | -0.4388 | No |
| 46 | AARS | AARS Entrez, Source | alanyl-tRNA synthetase | 8177 | -0.027 | -0.4406 | No |
| 47 | KIF4A | KIF4A Entrez, Source | kinesin family member 4A | 8274 | -0.029 | -0.4463 | No |
| 48 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 8322 | -0.030 | -0.4483 | No |
| 49 | SPIN | SPIN Entrez, Source | spindlin | 8397 | -0.032 | -0.4521 | No |
| 50 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 8700 | -0.039 | -0.4729 | No |
| 51 | SPINK1 | SPINK1 Entrez, Source | serine peptidase inhibitor, Kazal type 1 | 8891 | -0.043 | -0.4850 | No |
| 52 | IDE | IDE Entrez, Source | insulin-degrading enzyme | 8919 | -0.044 | -0.4846 | No |
| 53 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 8949 | -0.045 | -0.4845 | No |
| 54 | HCK | HCK Entrez, Source | hemopoietic cell kinase | 9107 | -0.049 | -0.4937 | No |
| 55 | TUBB2C | TUBB2C Entrez, Source | tubulin, beta 2C | 9110 | -0.049 | -0.4913 | No |
| 56 | CDKN3 | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 9252 | -0.053 | -0.4991 | No |
| 57 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 9560 | -0.061 | -0.5190 | No |
| 58 | ITGB7 | ITGB7 Entrez, Source | integrin, beta 7 | 9605 | -0.063 | -0.5190 | No |
| 59 | SLC29A1 | SLC29A1 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 1 | 9613 | -0.063 | -0.5162 | No |
| 60 | JUN | JUN Entrez, Source | jun oncogene | 9748 | -0.066 | -0.5228 | No |
| 61 | GALT | GALT Entrez, Source | galactose-1-phosphate uridylyltransferase | 9817 | -0.069 | -0.5242 | No |
| 62 | HDH | 9976 | -0.074 | -0.5323 | No | ||
| 63 | BRCA2 | BRCA2 Entrez, Source | breast cancer 2, early onset | 10026 | -0.075 | -0.5319 | No |
| 64 | RAB4B | RAB4B Entrez, Source | RAB4B, member RAS oncogene family | 10064 | -0.077 | -0.5307 | No |
| 65 | KIFC1 | KIFC1 Entrez, Source | kinesin family member C1 | 10247 | -0.083 | -0.5400 | No |
| 66 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 10400 | -0.088 | -0.5468 | No |
| 67 | CAPN1 | CAPN1 Entrez, Source | calpain 1, (mu/I) large subunit | 10465 | -0.091 | -0.5468 | No |
| 68 | SCN1B | SCN1B Entrez, Source | sodium channel, voltage-gated, type I, beta | 10536 | -0.093 | -0.5471 | No |
| 69 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 10538 | -0.093 | -0.5423 | No |
| 70 | MDN1 | MDN1 Entrez, Source | MDN1, midasin homolog (yeast) | 10751 | -0.101 | -0.5529 | No |
| 71 | PPP1CA | PPP1CA Entrez, Source | protein phosphatase 1, catalytic subunit, alpha isoform | 10852 | -0.105 | -0.5549 | No |
| 72 | FHL1 | FHL1 Entrez, Source | four and a half LIM domains 1 | 10972 | -0.110 | -0.5580 | Yes |
| 73 | PSMC3 | PSMC3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 10989 | -0.111 | -0.5533 | Yes |
| 74 | TUBB3 | TUBB3 Entrez, Source | tubulin, beta 3 | 11053 | -0.114 | -0.5520 | Yes |
| 75 | MYEF2 | MYEF2 Entrez, Source | myelin expression factor 2 | 11057 | -0.115 | -0.5461 | Yes |
| 76 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 11099 | -0.117 | -0.5430 | Yes |
| 77 | EIF2AK2 | EIF2AK2 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 2 | 11121 | -0.118 | -0.5382 | Yes |
| 78 | EDN2 | EDN2 Entrez, Source | endothelin 2 | 11154 | -0.119 | -0.5343 | Yes |
| 79 | LSP1 | LSP1 Entrez, Source | lymphocyte-specific protein 1 | 11156 | -0.119 | -0.5280 | Yes |
| 80 | ANP32A | ANP32A Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 11345 | -0.129 | -0.5354 | Yes |
| 81 | SSX2IP | SSX2IP Entrez, Source | synovial sarcoma, X breakpoint 2 interacting protein | 11580 | -0.142 | -0.5455 | Yes |
| 82 | NUDC | NUDC Entrez, Source | nuclear distribution gene C homolog (A. nidulans) | 11586 | -0.143 | -0.5382 | Yes |
| 83 | CIT | CIT Entrez, Source | citron (rho-interacting, serine/threonine kinase 21) | 11639 | -0.146 | -0.5344 | Yes |
| 84 | XPO1 | XPO1 Entrez, Source | exportin 1 (CRM1 homolog, yeast) | 11725 | -0.151 | -0.5328 | Yes |
| 85 | KIF2C | KIF2C Entrez, Source | kinesin family member 2C | 11889 | -0.164 | -0.5364 | Yes |
| 86 | SMC4 | SMC4 Entrez, Source | structural maintenance of chromosomes 4 | 11916 | -0.167 | -0.5294 | Yes |
| 87 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 12163 | -0.188 | -0.5380 | Yes |
| 88 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 12177 | -0.189 | -0.5289 | Yes |
| 89 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 12269 | -0.201 | -0.5251 | Yes |
| 90 | GSN | GSN Entrez, Source | gelsolin (amyloidosis, Finnish type) | 12307 | -0.205 | -0.5169 | Yes |
| 91 | RELN | RELN Entrez, Source | reelin | 12369 | -0.211 | -0.5103 | Yes |
| 92 | TMPO | TMPO Entrez, Source | thymopoietin | 12402 | -0.215 | -0.5012 | Yes |
| 93 | NT5DC2 | NT5DC2 Entrez, Source | 5'-nucleotidase domain containing 2 | 12442 | -0.220 | -0.4924 | Yes |
| 94 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 12504 | -0.229 | -0.4848 | Yes |
| 95 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 12519 | -0.231 | -0.4736 | Yes |
| 96 | AURKA | AURKA Entrez, Source | aurora kinase A | 12548 | -0.235 | -0.4631 | Yes |
| 97 | HMMR | HMMR Entrez, Source | hyaluronan-mediated motility receptor (RHAMM) | 12560 | -0.237 | -0.4513 | Yes |
| 98 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 12611 | -0.247 | -0.4419 | Yes |
| 99 | CKAP5 | CKAP5 Entrez, Source | cytoskeleton associated protein 5 | 12613 | -0.247 | -0.4288 | Yes |
| 100 | KIF22 | KIF22 Entrez, Source | kinesin family member 22 | 12713 | -0.267 | -0.4220 | Yes |
| 101 | CD151 | CD151 Entrez, Source | CD151 molecule (Raph blood group) | 12718 | -0.268 | -0.4080 | Yes |
| 102 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 12720 | -0.269 | -0.3937 | Yes |
| 103 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 12767 | -0.278 | -0.3824 | Yes |
| 104 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 12822 | -0.294 | -0.3708 | Yes |
| 105 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 12954 | -0.340 | -0.3626 | Yes |
| 106 | TUBB | TUBB Entrez, Source | tubulin, beta | 12961 | -0.344 | -0.3447 | Yes |
| 107 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 12986 | -0.357 | -0.3275 | Yes |
| 108 | CAPG | CAPG Entrez, Source | capping protein (actin filament), gelsolin-like | 13018 | -0.375 | -0.3098 | Yes |
| 109 | CDC2A | 13061 | -0.405 | -0.2913 | Yes | ||
| 110 | LIPC | LIPC Entrez, Source | lipase, hepatic | 13109 | -0.433 | -0.2718 | Yes |
| 111 | AURKB | AURKB Entrez, Source | aurora kinase B | 13112 | -0.438 | -0.2486 | Yes |
| 112 | CRIP2 | CRIP2 Entrez, Source | cysteine-rich protein 2 | 13214 | -0.582 | -0.2252 | Yes |
| 113 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 13247 | -0.677 | -0.1915 | Yes |
| 114 | LGALS3 | LGALS3 Entrez, Source | lectin, galactoside-binding, soluble, 3 (galectin 3) | 13253 | -0.689 | -0.1551 | Yes |
| 115 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13288 | -0.823 | -0.1138 | Yes |
| 116 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13289 | -0.828 | -0.0696 | Yes |
| 117 | PKIB | PKIB Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor beta | 13334 | -1.378 | 0.0006 | Yes |
