Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HOHENKIRK_MONOCYTE_DEND_UP |
| Enrichment Score (ES) | 0.5084545 |
| Normalized Enrichment Score (NES) | 1.8110006 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.012302518 |
| FWER p-Value | 0.858 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FCGR2B | FCGR2B Entrez, Source | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 12 | 1.056 | 0.0710 | Yes |
| 2 | APOC1 | APOC1 Entrez, Source | apolipoprotein C-I | 36 | 0.809 | 0.1244 | Yes |
| 3 | TNFAIP6 | TNFAIP6 Entrez, Source | tumor necrosis factor, alpha-induced protein 6 | 64 | 0.710 | 0.1707 | Yes |
| 4 | CBS | CBS Entrez, Source | cystathionine-beta-synthase | 158 | 0.523 | 0.1993 | Yes |
| 5 | LPL | LPL Entrez, Source | lipoprotein lipase | 230 | 0.451 | 0.2246 | Yes |
| 6 | ACOT2 | ACOT2 Entrez, Source | acyl-CoA thioesterase 2 | 231 | 0.450 | 0.2553 | Yes |
| 7 | GDF15 | GDF15 Entrez, Source | growth differentiation factor 15 | 237 | 0.445 | 0.2852 | Yes |
| 8 | MGLL | MGLL Entrez, Source | monoglyceride lipase | 241 | 0.443 | 0.3152 | Yes |
| 9 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 311 | 0.390 | 0.3365 | Yes |
| 10 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 325 | 0.381 | 0.3615 | Yes |
| 11 | ACAA2 | ACAA2 Entrez, Source | acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | 374 | 0.353 | 0.3819 | Yes |
| 12 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 383 | 0.346 | 0.4049 | Yes |
| 13 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 487 | 0.306 | 0.4179 | Yes |
| 14 | SLC11A2 | SLC11A2 Entrez, Source | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | 538 | 0.287 | 0.4337 | Yes |
| 15 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 540 | 0.287 | 0.4531 | Yes |
| 16 | TGFA | TGFA Entrez, Source | transforming growth factor, alpha | 740 | 0.230 | 0.4538 | Yes |
| 17 | CAT | CAT Entrez, Source | catalase | 884 | 0.209 | 0.4573 | Yes |
| 18 | PCBD1 | PCBD1 Entrez, Source | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) | 936 | 0.202 | 0.4671 | Yes |
| 19 | FABP4 | FABP4 Entrez, Source | fatty acid binding protein 4, adipocyte | 947 | 0.200 | 0.4800 | Yes |
| 20 | SULT1C1 | SULT1C1 Entrez, Source | sulfotransferase family, cytosolic, 1C, member 1 | 964 | 0.199 | 0.4923 | Yes |
| 21 | FABP5 | FABP5 Entrez, Source | fatty acid binding protein 5 (psoriasis-associated) | 1363 | 0.160 | 0.4732 | Yes |
| 22 | CEBPA | CEBPA Entrez, Source | CCAAT/enhancer binding protein (C/EBP), alpha | 1386 | 0.158 | 0.4823 | Yes |
| 23 | ENPP2 | ENPP2 Entrez, Source | ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) | 1416 | 0.156 | 0.4907 | Yes |
| 24 | A2M | A2M Entrez, Source | alpha-2-macroglobulin | 1433 | 0.155 | 0.5000 | Yes |
| 25 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 1460 | 0.152 | 0.5085 | Yes |
| 26 | DPP4 | DPP4 Entrez, Source | dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) | 1919 | 0.125 | 0.4825 | No |
| 27 | CD86 | CD86 Entrez, Source | CD86 molecule | 2005 | 0.121 | 0.4843 | No |
| 28 | SCARB1 | SCARB1 Entrez, Source | scavenger receptor class B, member 1 | 2252 | 0.112 | 0.4734 | No |
| 29 | C1QB | C1QB Entrez, Source | complement component 1, q subcomponent, B chain | 2588 | 0.100 | 0.4549 | No |
| 30 | CYB5A | CYB5A Entrez, Source | cytochrome b5 type A (microsomal) | 2608 | 0.099 | 0.4602 | No |
| 31 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 2802 | 0.091 | 0.4519 | No |
| 32 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 3275 | 0.077 | 0.4215 | No |
| 33 | ST6GAL1 | ST6GAL1 Entrez, Source | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 3300 | 0.076 | 0.4249 | No |
| 34 | F13A1 | F13A1 Entrez, Source | coagulation factor XIII, A1 polypeptide | 3304 | 0.076 | 0.4298 | No |
| 35 | CCL22 | CCL22 Entrez, Source | chemokine (C-C motif) ligand 22 | 3377 | 0.074 | 0.4294 | No |
| 36 | PTPRO | PTPRO Entrez, Source | protein tyrosine phosphatase, receptor type, O | 3457 | 0.072 | 0.4284 | No |
| 37 | GATM | GATM Entrez, Source | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 3691 | 0.067 | 0.4154 | No |
| 38 | CSF1 | CSF1 Entrez, Source | colony stimulating factor 1 (macrophage) | 3716 | 0.066 | 0.4180 | No |
| 39 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 3806 | 0.064 | 0.4157 | No |
| 40 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 3998 | 0.059 | 0.4053 | No |
| 41 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 4054 | 0.058 | 0.4051 | No |
| 42 | DNASE1L3 | DNASE1L3 Entrez, Source | deoxyribonuclease I-like 3 | 4230 | 0.054 | 0.3956 | No |
| 43 | MMP12 | MMP12 Entrez, Source | matrix metallopeptidase 12 (macrophage elastase) | 4703 | 0.044 | 0.3630 | No |
| 44 | ALOX15 | ALOX15 Entrez, Source | arachidonate 15-lipoxygenase | 4728 | 0.043 | 0.3642 | No |
| 45 | RNASE6 | RNASE6 Entrez, Source | ribonuclease, RNase A family, k6 | 4848 | 0.041 | 0.3580 | No |
| 46 | CCNA1 | CCNA1 Entrez, Source | cyclin A1 | 5345 | 0.031 | 0.3227 | No |
| 47 | CDH1 | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 5558 | 0.026 | 0.3085 | No |
| 48 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 5560 | 0.026 | 0.3102 | No |
| 49 | CCL17 | CCL17 Entrez, Source | chemokine (C-C motif) ligand 17 | 5765 | 0.023 | 0.2964 | No |
| 50 | SLA | SLA Entrez, Source | Src-like-adaptor | 5835 | 0.021 | 0.2927 | No |
| 51 | NR4A3 | NR4A3 Entrez, Source | nuclear receptor subfamily 4, group A, member 3 | 5891 | 0.020 | 0.2899 | No |
| 52 | CTSC | CTSC Entrez, Source | cathepsin C | 6008 | 0.018 | 0.2824 | No |
| 53 | HMGN3 | HMGN3 Entrez, Source | high mobility group nucleosomal binding domain 3 | 6294 | 0.012 | 0.2617 | No |
| 54 | TOMM40 | TOMM40 Entrez, Source | translocase of outer mitochondrial membrane 40 homolog (yeast) | 6598 | 0.006 | 0.2393 | No |
| 55 | CCNH | CCNH Entrez, Source | cyclin H | 7280 | -0.008 | 0.1885 | No |
| 56 | INHBA | INHBA Entrez, Source | inhibin, beta A (activin A, activin AB alpha polypeptide) | 7375 | -0.010 | 0.1820 | No |
| 57 | ECM1 | ECM1 Entrez, Source | extracellular matrix protein 1 | 7713 | -0.017 | 0.1578 | No |
| 58 | RAP1GAP | RAP1GAP Entrez, Source | RAP1 GTPase activating protein | 7792 | -0.018 | 0.1532 | No |
| 59 | TGM2 | TGM2 Entrez, Source | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 7842 | -0.020 | 0.1508 | No |
| 60 | ARF4 | ARF4 Entrez, Source | ADP-ribosylation factor 4 | 7998 | -0.023 | 0.1407 | No |
| 61 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 8124 | -0.026 | 0.1330 | No |
| 62 | GAS6 | GAS6 Entrez, Source | growth arrest-specific 6 | 8485 | -0.034 | 0.1082 | No |
| 63 | PEBP1 | PEBP1 Entrez, Source | phosphatidylethanolamine binding protein 1 | 9172 | -0.051 | 0.0599 | No |
| 64 | AES | AES Entrez, Source | amino-terminal enhancer of split | 9813 | -0.069 | 0.0163 | No |
| 65 | KCNAB2 | KCNAB2 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, beta member 2 | 9914 | -0.072 | 0.0137 | No |
| 66 | SPINT2 | SPINT2 Entrez, Source | serine peptidase inhibitor, Kunitz type, 2 | 9927 | -0.073 | 0.0177 | No |
| 67 | ACOT7 | ACOT7 Entrez, Source | acyl-CoA thioesterase 7 | 9973 | -0.074 | 0.0194 | No |
| 68 | CRABP2 | CRABP2 Entrez, Source | cellular retinoic acid binding protein 2 | 10545 | -0.093 | -0.0174 | No |
| 69 | QSCN6 | QSCN6 Entrez, Source | quiescin Q6 | 10576 | -0.094 | -0.0132 | No |
| 70 | ITPKB | ITPKB Entrez, Source | inositol 1,4,5-trisphosphate 3-kinase B | 10615 | -0.096 | -0.0096 | No |
| 71 | SNRPN | SNRPN Entrez, Source | small nuclear ribonucleoprotein polypeptide N | 10931 | -0.108 | -0.0260 | No |
| 72 | CD74 | CD74 Entrez, Source | CD74 molecule, major histocompatibility complex, class II invariant chain | 10944 | -0.109 | -0.0194 | No |
| 73 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 11087 | -0.116 | -0.0223 | No |
| 74 | PDLIM4 | PDLIM4 Entrez, Source | PDZ and LIM domain 4 | 11133 | -0.119 | -0.0176 | No |
| 75 | ATP1B1 | ATP1B1 Entrez, Source | ATPase, Na+/K+ transporting, beta 1 polypeptide | 11599 | -0.144 | -0.0429 | No |
| 76 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 11683 | -0.149 | -0.0390 | No |
| 77 | FABP3 | FABP3 Entrez, Source | fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) | 12473 | -0.224 | -0.0833 | No |
| 78 | PFKM | PFKM Entrez, Source | phosphofructokinase, muscle | 13007 | -0.369 | -0.0983 | No |
| 79 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 13016 | -0.374 | -0.0735 | No |
| 80 | ABCG1 | ABCG1 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 1 | 13094 | -0.421 | -0.0506 | No |
| 81 | LGALS3BP | LGALS3BP Entrez, Source | lectin, galactoside-binding, soluble, 3 binding protein | 13114 | -0.440 | -0.0220 | No |
| 82 | PPIC | PPIC Entrez, Source | peptidylprolyl isomerase C (cyclophilin C) | 13206 | -0.575 | 0.0103 | No |
