Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HSA00020_CITRATE_CYCLE |
| Enrichment Score (ES) | 0.6650961 |
| Normalized Enrichment Score (NES) | 1.7947261 |
| Nominal p-value | 0.007936508 |
| FDR q-value | 0.014875049 |
| FWER p-Value | 0.905 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PC | PC Entrez, Source | pyruvate carboxylase | 79 | 0.652 | 0.1956 | Yes |
| 2 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 167 | 0.505 | 0.3452 | Yes |
| 3 | ACLY | ACLY Entrez, Source | ATP citrate lyase | 186 | 0.487 | 0.4942 | Yes |
| 4 | CLYBL | CLYBL Entrez, Source | citrate lyase beta like | 251 | 0.433 | 0.6230 | Yes |
| 5 | IDH1 | IDH1 Entrez, Source | isocitrate dehydrogenase 1 (NADP+), soluble | 1183 | 0.172 | 0.6063 | Yes |
| 6 | SDHD | SDHD Entrez, Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 1404 | 0.157 | 0.6382 | Yes |
| 7 | DLD | DLD Entrez, Source | dihydrolipoamide dehydrogenase | 1628 | 0.141 | 0.6651 | Yes |
| 8 | MDH1 | MDH1 Entrez, Source | malate dehydrogenase 1, NAD (soluble) | 2361 | 0.108 | 0.6436 | No |
| 9 | SDHA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 2886 | 0.088 | 0.6316 | No |
| 10 | ACO1 | ACO1 Entrez, Source | aconitase 1, soluble | 3429 | 0.073 | 0.6134 | No |
| 11 | IDH3B | IDH3B Entrez, Source | isocitrate dehydrogenase 3 (NAD+) beta | 3545 | 0.070 | 0.6264 | No |
| 12 | SDHC | SDHC Entrez, Source | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 3898 | 0.062 | 0.6191 | No |
| 13 | MDH2 | MDH2 Entrez, Source | malate dehydrogenase 2, NAD (mitochondrial) | 4168 | 0.056 | 0.6161 | No |
| 14 | ACO2 | ACO2 Entrez, Source | aconitase 2, mitochondrial | 4353 | 0.052 | 0.6182 | No |
| 15 | SUCLG2 | SUCLG2 Entrez, Source | succinate-CoA ligase, GDP-forming, beta subunit | 4416 | 0.050 | 0.6291 | No |
| 16 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 4884 | 0.040 | 0.6065 | No |
| 17 | SUCLG1 | SUCLG1 Entrez, Source | succinate-CoA ligase, GDP-forming, alpha subunit | 5260 | 0.033 | 0.5884 | No |
| 18 | IDH3A | IDH3A Entrez, Source | isocitrate dehydrogenase 3 (NAD+) alpha | 6433 | 0.009 | 0.5032 | No |
| 19 | CS | CS Entrez, Source | citrate synthase | 7513 | -0.013 | 0.4262 | No |
| 20 | IDH3G | IDH3G Entrez, Source | isocitrate dehydrogenase 3 (NAD+) gamma | 8587 | -0.037 | 0.3569 | No |
