Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HSA00150_ANDROGEN_AND_ESTROGEN_METABOLISM |
| Enrichment Score (ES) | 0.72037655 |
| Normalized Enrichment Score (NES) | 2.0274181 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0011795462 |
| FWER p-Value | 0.091 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | UGT2A1 | UGT2A1 Entrez, Source | UDP glucuronosyltransferase 2 family, polypeptide A1 | 25 | 0.863 | 0.1841 | Yes |
| 2 | HSD17B7 | HSD17B7 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 7 | 74 | 0.685 | 0.3281 | Yes |
| 3 | HSD17B2 | HSD17B2 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 2 | 280 | 0.415 | 0.4021 | Yes |
| 4 | HSD3B1 | HSD3B1 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 293 | 0.402 | 0.4877 | Yes |
| 5 | SRD5A1 | SRD5A1 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 343 | 0.371 | 0.5639 | Yes |
| 6 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 487 | 0.306 | 0.6191 | Yes |
| 7 | SULT1E1 | SULT1E1 Entrez, Source | sulfotransferase family 1E, estrogen-preferring, member 1 | 571 | 0.277 | 0.6726 | Yes |
| 8 | AKR1D1 | AKR1D1 Entrez, Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 656 | 0.251 | 0.7204 | Yes |
| 9 | STS | STS Entrez, Source | steroid sulfatase (microsomal), arylsulfatase C, isozyme S | 1743 | 0.134 | 0.6678 | No |
| 10 | ARSE | ARSE Entrez, Source | arylsulfatase E (chondrodysplasia punctata 1) | 2110 | 0.117 | 0.6656 | No |
| 11 | HSD17B1 | HSD17B1 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 1 | 2150 | 0.116 | 0.6877 | No |
| 12 | HSD17B3 | HSD17B3 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 3 | 2606 | 0.099 | 0.6749 | No |
| 13 | SULT2A1 | SULT2A1 Entrez, Source | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 2731 | 0.094 | 0.6859 | No |
| 14 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 2909 | 0.088 | 0.6915 | No |
| 15 | HSD17B8 | HSD17B8 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 8 | 3280 | 0.077 | 0.6803 | No |
| 16 | HSD17B12 | HSD17B12 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 12 | 5100 | 0.036 | 0.5514 | No |
| 17 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 6111 | 0.016 | 0.4790 | No |
| 18 | PRMT3 | PRMT3 Entrez, Source | protein arginine methyltransferase 3 | 6340 | 0.011 | 0.4642 | No |
| 19 | SRD5A2 | SRD5A2 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 6493 | 0.008 | 0.4545 | No |
| 20 | CYP11B1 | CYP11B1 Entrez, Source | cytochrome P450, family 11, subfamily B, polypeptide 1 | 7700 | -0.017 | 0.3676 | No |
| 21 | CARM1 | CARM1 Entrez, Source | coactivator-associated arginine methyltransferase 1 | 8288 | -0.030 | 0.3299 | No |
| 22 | METTL6 | METTL6 Entrez, Source | methyltransferase like 6 | 8429 | -0.033 | 0.3264 | No |
| 23 | LCMT2 | LCMT2 Entrez, Source | leucine carboxyl methyltransferase 2 | 8973 | -0.045 | 0.2954 | No |
| 24 | PRMT2 | PRMT2 Entrez, Source | protein arginine methyltransferase 2 | 9909 | -0.072 | 0.2407 | No |
| 25 | LCMT1 | LCMT1 Entrez, Source | leucine carboxyl methyltransferase 1 | 10118 | -0.079 | 0.2421 | No |
