Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HSA00251_GLUTAMATE_METABOLISM |
| Enrichment Score (ES) | 0.6399891 |
| Normalized Enrichment Score (NES) | 1.7918597 |
| Nominal p-value | 0.0020242915 |
| FDR q-value | 0.015229399 |
| FWER p-Value | 0.911 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 56 | 0.731 | 0.1662 | Yes |
| 2 | CPS1 | CPS1 Entrez, Source | carbamoyl-phosphate synthetase 1, mitochondrial | 91 | 0.631 | 0.3109 | Yes |
| 3 | GPT | GPT Entrez, Source | glutamic-pyruvate transaminase (alanine aminotransferase) | 137 | 0.555 | 0.4370 | Yes |
| 4 | GLS2 | GLS2 Entrez, Source | glutaminase 2 (liver, mitochondrial) | 291 | 0.403 | 0.5195 | Yes |
| 5 | ABAT | ABAT Entrez, Source | 4-aminobutyrate aminotransferase | 450 | 0.320 | 0.5824 | Yes |
| 6 | ALDH5A1 | ALDH5A1 Entrez, Source | aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 870 | 0.211 | 0.6002 | Yes |
| 7 | NADSYN1 | NADSYN1 Entrez, Source | NAD synthetase 1 | 959 | 0.199 | 0.6400 | Yes |
| 8 | GLUD1 | GLUD1 Entrez, Source | glutamate dehydrogenase 1 | 1864 | 0.128 | 0.6020 | No |
| 9 | EPRS | EPRS Entrez, Source | glutamyl-prolyl-tRNA synthetase | 2170 | 0.115 | 0.6060 | No |
| 10 | GSS | GSS Entrez, Source | glutathione synthetase | 3596 | 0.069 | 0.5150 | No |
| 11 | GSR | GSR Entrez, Source | glutathione reductase | 4018 | 0.059 | 0.4972 | No |
| 12 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 5183 | 0.034 | 0.4178 | No |
| 13 | GLUL | GLUL Entrez, Source | glutamate-ammonia ligase (glutamine synthetase) | 6150 | 0.015 | 0.3489 | No |
| 14 | GCLC | GCLC Entrez, Source | glutamate-cysteine ligase, catalytic subunit | 6525 | 0.007 | 0.3225 | No |
| 15 | GFPT1 | GFPT1 Entrez, Source | glutamine-fructose-6-phosphate transaminase 1 | 6698 | 0.004 | 0.3105 | No |
| 16 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 7234 | -0.007 | 0.2720 | No |
| 17 | NAGK | NAGK Entrez, Source | N-acetylglucosamine kinase | 7948 | -0.022 | 0.2237 | No |
| 18 | GCLM | GCLM Entrez, Source | glutamate-cysteine ligase, modifier subunit | 8939 | -0.045 | 0.1597 | No |
| 19 | GFPT2 | GFPT2 Entrez, Source | glutamine-fructose-6-phosphate transaminase 2 | 9121 | -0.049 | 0.1576 | No |
| 20 | GAD2 | GAD2 Entrez, Source | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 9551 | -0.061 | 0.1396 | No |
| 21 | PPAT | PPAT Entrez, Source | phosphoribosyl pyrophosphate amidotransferase | 10398 | -0.088 | 0.0967 | No |
| 22 | GMPS | GMPS Entrez, Source | guanine monphosphate synthetase | 10477 | -0.091 | 0.1120 | No |
| 23 | GLS | GLS Entrez, Source | glutaminase | 13118 | -0.442 | 0.0168 | No |
