Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HSA00330_ARGININE_AND_PROLINE_METABOLISM |
| Enrichment Score (ES) | 0.6217231 |
| Normalized Enrichment Score (NES) | 1.6773627 |
| Nominal p-value | 0.0020491802 |
| FDR q-value | 0.039845 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 49 | 0.765 | 0.1386 | Yes |
| 2 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 56 | 0.731 | 0.2740 | Yes |
| 3 | CPS1 | CPS1 Entrez, Source | carbamoyl-phosphate synthetase 1, mitochondrial | 91 | 0.631 | 0.3889 | Yes |
| 4 | ASL | ASL Entrez, Source | argininosuccinate lyase | 122 | 0.586 | 0.4956 | Yes |
| 5 | ARG1 | ARG1 Entrez, Source | arginase, liver | 246 | 0.438 | 0.5677 | Yes |
| 6 | ASS1 | ASS1 Entrez, Source | argininosuccinate synthetase 1 | 598 | 0.267 | 0.5911 | Yes |
| 7 | GAMT | GAMT Entrez, Source | guanidinoacetate N-methyltransferase | 753 | 0.227 | 0.6217 | Yes |
| 8 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 1460 | 0.152 | 0.5970 | No |
| 9 | NOS3 | NOS3 Entrez, Source | nitric oxide synthase 3 (endothelial cell) | 1840 | 0.129 | 0.5926 | No |
| 10 | GLUD1 | GLUD1 Entrez, Source | glutamate dehydrogenase 1 | 1864 | 0.128 | 0.6146 | No |
| 11 | EPRS | EPRS Entrez, Source | glutamyl-prolyl-tRNA synthetase | 2170 | 0.115 | 0.6132 | No |
| 12 | PYCRL | PYCRL Entrez, Source | pyrroline-5-carboxylate reductase-like | 2349 | 0.108 | 0.6200 | No |
| 13 | CKMT1A | CKMT1A Entrez, Source | creatine kinase, mitochondrial 1A | 2644 | 0.098 | 0.6161 | No |
| 14 | LAP3 | LAP3 Entrez, Source | leucine aminopeptidase 3 | 3371 | 0.074 | 0.5754 | No |
| 15 | ARG2 | ARG2 Entrez, Source | arginase, type II | 3449 | 0.072 | 0.5831 | No |
| 16 | GATM | GATM Entrez, Source | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 3691 | 0.067 | 0.5774 | No |
| 17 | NOS1 | NOS1 Entrez, Source | nitric oxide synthase 1 (neuronal) | 4800 | 0.042 | 0.5020 | No |
| 18 | PRODH | PRODH Entrez, Source | proline dehydrogenase (oxidase) 1 | 5569 | 0.026 | 0.4492 | No |
| 19 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 7234 | -0.007 | 0.3256 | No |
| 20 | CKM | CKM Entrez, Source | creatine kinase, muscle | 10056 | -0.076 | 0.1280 | No |
| 21 | P4HA1 | P4HA1 Entrez, Source | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I | 11102 | -0.117 | 0.0713 | No |
| 22 | PYCR2 | PYCR2 Entrez, Source | pyrroline-5-carboxylate reductase family, member 2 | 11972 | -0.171 | 0.0378 | No |
| 23 | CKB | CKB Entrez, Source | creatine kinase, brain | 12974 | -0.349 | 0.0276 | No |
