Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HSA00410_BETA_ALANINE_METABOLISM |
| Enrichment Score (ES) | 0.6564818 |
| Normalized Enrichment Score (NES) | 1.8470576 |
| Nominal p-value | 0.0022522523 |
| FDR q-value | 0.008861724 |
| FWER p-Value | 0.724 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 24 | 0.864 | 0.1517 | Yes |
| 2 | ABP1 | ABP1 Entrez, Source | amiloride binding protein 1 (amine oxidase (copper-containing)) | 109 | 0.606 | 0.2529 | Yes |
| 3 | UPB1 | UPB1 Entrez, Source | ureidopropionase, beta | 162 | 0.519 | 0.3412 | Yes |
| 4 | DPYD | DPYD Entrez, Source | dihydropyrimidine dehydrogenase | 168 | 0.502 | 0.4299 | Yes |
| 5 | DPYS | DPYS Entrez, Source | dihydropyrimidinase | 253 | 0.432 | 0.5002 | Yes |
| 6 | ECHS1 | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 260 | 0.427 | 0.5756 | Yes |
| 7 | ABAT | ABAT Entrez, Source | 4-aminobutyrate aminotransferase | 450 | 0.320 | 0.6183 | Yes |
| 8 | MLYCD | MLYCD Entrez, Source | malonyl-CoA decarboxylase | 584 | 0.271 | 0.6565 | Yes |
| 9 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 1399 | 0.157 | 0.6232 | No |
| 10 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 1403 | 0.157 | 0.6508 | No |
| 11 | SRM | SRM Entrez, Source | spermidine synthase | 1809 | 0.131 | 0.6436 | No |
| 12 | ALDH7A1 | ALDH7A1 Entrez, Source | aldehyde dehydrogenase 7 family, member A1 | 2281 | 0.111 | 0.6280 | No |
| 13 | HIBCH | HIBCH Entrez, Source | 3-hydroxyisobutyryl-Coenzyme A hydrolase | 2413 | 0.106 | 0.6370 | No |
| 14 | CNDP1 | CNDP1 Entrez, Source | carnosine dipeptidase 1 (metallopeptidase M20 family) | 2792 | 0.092 | 0.6249 | No |
| 15 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 4305 | 0.053 | 0.5208 | No |
| 16 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 4310 | 0.053 | 0.5298 | No |
| 17 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 4870 | 0.040 | 0.4950 | No |
| 18 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 5183 | 0.034 | 0.4777 | No |
| 19 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 6279 | 0.012 | 0.3977 | No |
| 20 | GAD2 | GAD2 Entrez, Source | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 9551 | -0.061 | 0.1629 | No |
| 21 | ALDH1B1 | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 10696 | -0.098 | 0.0945 | No |
| 22 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 11983 | -0.171 | 0.0284 | No |
| 23 | SMS | SMS Entrez, Source | spermine synthase | 13083 | -0.414 | 0.0194 | No |
