Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HSA00650_BUTANOATE_METABOLISM |
| Enrichment Score (ES) | 0.73368174 |
| Normalized Enrichment Score (NES) | 2.1907513 |
| Nominal p-value | 0.0 |
| FDR q-value | 6.688698E-5 |
| FWER p-Value | 0.0030 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 24 | 0.864 | 0.1198 | Yes |
| 2 | AADAC | AADAC Entrez, Source | arylacetamide deacetylase (esterase) | 97 | 0.619 | 0.2015 | Yes |
| 3 | ACAT2 | ACAT2 Entrez, Source | acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) | 172 | 0.499 | 0.2662 | Yes |
| 4 | HMGCS1 | HMGCS1 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) | 199 | 0.477 | 0.3313 | Yes |
| 5 | ECHS1 | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 260 | 0.427 | 0.3869 | Yes |
| 6 | HMGCL | HMGCL Entrez, Source | 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria) | 344 | 0.371 | 0.4328 | Yes |
| 7 | HMGCS2 | HMGCS2 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) | 360 | 0.358 | 0.4820 | Yes |
| 8 | ACAT1 | ACAT1 Entrez, Source | acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) | 430 | 0.329 | 0.5232 | Yes |
| 9 | ABAT | ABAT Entrez, Source | 4-aminobutyrate aminotransferase | 450 | 0.320 | 0.5668 | Yes |
| 10 | PDHA2 | PDHA2 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 2 | 663 | 0.250 | 0.5860 | Yes |
| 11 | AACS | AACS Entrez, Source | acetoacetyl-CoA synthetase | 771 | 0.224 | 0.6096 | Yes |
| 12 | PDHB | PDHB Entrez, Source | pyruvate dehydrogenase (lipoamide) beta | 858 | 0.213 | 0.6330 | Yes |
| 13 | ALDH5A1 | ALDH5A1 Entrez, Source | aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 870 | 0.211 | 0.6619 | Yes |
| 14 | HSD17B4 | HSD17B4 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 4 | 1074 | 0.185 | 0.6727 | Yes |
| 15 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 1296 | 0.164 | 0.6792 | Yes |
| 16 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 1399 | 0.157 | 0.6936 | Yes |
| 17 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 1403 | 0.157 | 0.7154 | Yes |
| 18 | HADH | HADH Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase | 1615 | 0.142 | 0.7196 | Yes |
| 19 | BDH1 | BDH1 Entrez, Source | 3-hydroxybutyrate dehydrogenase, type 1 | 1686 | 0.138 | 0.7337 | Yes |
| 20 | RDH11 | RDH11 Entrez, Source | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 2018 | 0.121 | 0.7258 | No |
| 21 | ALDH7A1 | ALDH7A1 Entrez, Source | aldehyde dehydrogenase 7 family, member A1 | 2281 | 0.111 | 0.7218 | No |
| 22 | DDHD1 | DDHD1 Entrez, Source | DDHD domain containing 1 | 2904 | 0.088 | 0.6874 | No |
| 23 | AKR1B10 | AKR1B10 Entrez, Source | aldo-keto reductase family 1, member B10 (aldose reductase) | 4097 | 0.057 | 0.6059 | No |
| 24 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 4305 | 0.053 | 0.5978 | No |
| 25 | PLA1A | PLA1A Entrez, Source | phospholipase A1 member A | 4469 | 0.049 | 0.5924 | No |
| 26 | PDHA1 | PDHA1 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 1 | 4772 | 0.042 | 0.5757 | No |
| 27 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 5183 | 0.034 | 0.5497 | No |
| 28 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 6279 | 0.012 | 0.4691 | No |
| 29 | PRDX6 | PRDX6 Entrez, Source | peroxiredoxin 6 | 6850 | 0.001 | 0.4265 | No |
| 30 | HSD3B7 | HSD3B7 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 8334 | -0.031 | 0.3194 | No |
| 31 | GAD2 | GAD2 Entrez, Source | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 9551 | -0.061 | 0.2366 | No |
| 32 | PPME1 | PPME1 Entrez, Source | protein phosphatase methylesterase 1 | 9891 | -0.071 | 0.2212 | No |
| 33 | ALDH1B1 | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 10696 | -0.098 | 0.1746 | No |
| 34 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 11983 | -0.171 | 0.1021 | No |
