Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HSA00710_CARBON_FIXATION |
| Enrichment Score (ES) | 0.7465702 |
| Normalized Enrichment Score (NES) | 1.8749626 |
| Nominal p-value | 0.002004008 |
| FDR q-value | 0.0066958326 |
| FWER p-Value | 0.569 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 56 | 0.731 | 0.2015 | Yes |
| 2 | FBP1 | FBP1 Entrez, Source | fructose-1,6-bisphosphatase 1 | 66 | 0.702 | 0.3986 | Yes |
| 3 | GPT | GPT Entrez, Source | glutamic-pyruvate transaminase (alanine aminotransferase) | 137 | 0.555 | 0.5497 | Yes |
| 4 | PKLR | PKLR Entrez, Source | pyruvate kinase, liver and RBC | 184 | 0.487 | 0.6835 | Yes |
| 5 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 666 | 0.249 | 0.7175 | Yes |
| 6 | ALDOC | ALDOC Entrez, Source | aldolase C, fructose-bisphosphate | 1047 | 0.187 | 0.7417 | Yes |
| 7 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1535 | 0.147 | 0.7466 | Yes |
| 8 | MDH1 | MDH1 Entrez, Source | malate dehydrogenase 1, NAD (soluble) | 2361 | 0.108 | 0.7151 | No |
| 9 | FBP2 | FBP2 Entrez, Source | fructose-1,6-bisphosphatase 2 | 2767 | 0.093 | 0.7110 | No |
| 10 | TPI1 | TPI1 Entrez, Source | triosephosphate isomerase 1 | 3163 | 0.080 | 0.7037 | No |
| 11 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 3566 | 0.069 | 0.6931 | No |
| 12 | MDH2 | MDH2 Entrez, Source | malate dehydrogenase 2, NAD (mitochondrial) | 4168 | 0.056 | 0.6637 | No |
| 13 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 7234 | -0.007 | 0.4357 | No |
| 14 | TKT | TKT Entrez, Source | transketolase (Wernicke-Korsakoff syndrome) | 7534 | -0.013 | 0.4170 | No |
| 15 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 9745 | -0.066 | 0.2699 | No |
