Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | HSA01430_CELL_COMMUNICATION |
| Enrichment Score (ES) | -0.5901612 |
| Normalized Enrichment Score (NES) | -1.875649 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.026980726 |
| FWER p-Value | 0.591 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GJB2 | GJB2 Entrez, Source | gap junction protein, beta 2, 26kDa (connexin 26) | 37 | 0.807 | 0.0747 | No |
| 2 | COL5A3 | COL5A3 Entrez, Source | collagen, type V, alpha 3 | 139 | 0.553 | 0.1203 | No |
| 3 | VTN | VTN Entrez, Source | vitronectin | 766 | 0.225 | 0.0948 | No |
| 4 | GJB1 | GJB1 Entrez, Source | gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked) | 1150 | 0.176 | 0.0829 | No |
| 5 | LAMA3 | LAMA3 Entrez, Source | laminin, alpha 3 | 1875 | 0.127 | 0.0406 | No |
| 6 | COL6A2 | COL6A2 Entrez, Source | collagen, type VI, alpha 2 | 2097 | 0.118 | 0.0353 | No |
| 7 | GJA5 | GJA5 Entrez, Source | gap junction protein, alpha 5, 40kDa (connexin 40) | 2591 | 0.100 | 0.0078 | No |
| 8 | COL11A1 | COL11A1 Entrez, Source | collagen, type XI, alpha 1 | 2613 | 0.099 | 0.0157 | No |
| 9 | KRT25 | KRT25 Entrez, Source | keratin 25 | 2622 | 0.098 | 0.0245 | No |
| 10 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 3806 | 0.064 | -0.0583 | No |
| 11 | VWF | VWF Entrez, Source | von Willebrand factor | 4369 | 0.051 | -0.0957 | No |
| 12 | COL2A1 | COL2A1 Entrez, Source | collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) | 4714 | 0.044 | -0.1174 | No |
| 13 | TNR | TNR Entrez, Source | tenascin R (restrictin, janusin) | 5041 | 0.037 | -0.1383 | No |
| 14 | THBS4 | THBS4 Entrez, Source | thrombospondin 4 | 5218 | 0.034 | -0.1483 | No |
| 15 | COMP | COMP Entrez, Source | cartilage oligomeric matrix protein | 5328 | 0.031 | -0.1535 | No |
| 16 | IBSP | IBSP Entrez, Source | integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II) | 5397 | 0.030 | -0.1557 | No |
| 17 | COL5A1 | COL5A1 Entrez, Source | collagen, type V, alpha 1 | 5666 | 0.024 | -0.1735 | No |
| 18 | DSC2 | DSC2 Entrez, Source | desmocollin 2 | 5772 | 0.022 | -0.1793 | No |
| 19 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 6077 | 0.017 | -0.2006 | No |
| 20 | GJA4 | GJA4 Entrez, Source | gap junction protein, alpha 4, 37kDa (connexin 37) | 6569 | 0.007 | -0.2369 | No |
| 21 | GJB6 | GJB6 Entrez, Source | gap junction protein, beta 6 (connexin 30) | 7028 | -0.003 | -0.2711 | No |
| 22 | GJA3 | GJA3 Entrez, Source | gap junction protein, alpha 3, 46kDa (connexin 46) | 7150 | -0.005 | -0.2797 | No |
| 23 | LAMB3 | LAMB3 Entrez, Source | laminin, beta 3 | 7303 | -0.008 | -0.2903 | No |
| 24 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 7328 | -0.009 | -0.2913 | No |
| 25 | COL4A4 | COL4A4 Entrez, Source | collagen, type IV, alpha 4 | 7382 | -0.010 | -0.2943 | No |
| 26 | CHAD | CHAD Entrez, Source | chondroadherin | 8079 | -0.025 | -0.3443 | No |
| 27 | DES | DES Entrez, Source | desmin | 8928 | -0.044 | -0.4038 | No |
| 28 | FN1 | FN1 Entrez, Source | fibronectin 1 | 9917 | -0.072 | -0.4712 | No |
| 29 | GJB4 | GJB4 Entrez, Source | gap junction protein, beta 4 (connexin 30.3) | 10324 | -0.086 | -0.4935 | No |
| 30 | ACTB | ACTB Entrez, Source | actin, beta | 10590 | -0.095 | -0.5043 | No |
| 31 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 11329 | -0.128 | -0.5476 | No |
| 32 | ITGB4 | ITGB4 Entrez, Source | integrin, beta 4 | 11844 | -0.160 | -0.5709 | No |
| 33 | GJB3 | GJB3 Entrez, Source | gap junction protein, beta 3, 31kDa (connexin 31) | 12077 | -0.180 | -0.5711 | Yes |
| 34 | GJB5 | GJB5 Entrez, Source | gap junction protein, beta 5 (connexin 31.1) | 12331 | -0.208 | -0.5702 | Yes |
| 35 | LMNA | LMNA Entrez, Source | lamin A/C | 12337 | -0.209 | -0.5505 | Yes |
| 36 | RELN | RELN Entrez, Source | reelin | 12369 | -0.211 | -0.5325 | Yes |
| 37 | LAMC2 | LAMC2 Entrez, Source | laminin, gamma 2 | 12640 | -0.252 | -0.5287 | Yes |
| 38 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 12719 | -0.269 | -0.5087 | Yes |
| 39 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 12760 | -0.277 | -0.4851 | Yes |
| 40 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 12818 | -0.293 | -0.4613 | Yes |
| 41 | LAMC1 | LAMC1 Entrez, Source | laminin, gamma 1 (formerly LAMB2) | 12835 | -0.298 | -0.4339 | Yes |
| 42 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 12902 | -0.323 | -0.4078 | Yes |
| 43 | GJA1 | GJA1 Entrez, Source | gap junction protein, alpha 1, 43kDa (connexin 43) | 13000 | -0.365 | -0.3801 | Yes |
| 44 | KRT20 | KRT20 Entrez, Source | keratin 20 | 13006 | -0.369 | -0.3450 | Yes |
| 45 | VIM | VIM Entrez, Source | vimentin | 13164 | -0.501 | -0.3087 | Yes |
| 46 | LAMA5 | LAMA5 Entrez, Source | laminin, alpha 5 | 13171 | -0.510 | -0.2602 | Yes |
| 47 | COL4A1 | COL4A1 Entrez, Source | collagen, type IV, alpha 1 | 13269 | -0.760 | -0.1945 | Yes |
| 48 | LAMB2 | LAMB2 Entrez, Source | laminin, beta 2 (laminin S) | 13313 | -1.021 | -0.0997 | Yes |
| 49 | NES | NES Entrez, Source | nestin | 13320 | -1.060 | 0.0017 | Yes |
