Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | HSA04330_NOTCH_SIGNALING_PATHWAY |
| Enrichment Score (ES) | -0.60030097 |
| Normalized Enrichment Score (NES) | -1.6979077 |
| Nominal p-value | 0.009727626 |
| FDR q-value | 0.07812418 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 2102 | 0.118 | -0.1284 | No |
| 2 | DLL3 | DLL3 Entrez, Source | delta-like 3 (Drosophila) | 2604 | 0.099 | -0.1413 | No |
| 3 | NOTCH3 | NOTCH3 Entrez, Source | Notch homolog 3 (Drosophila) | 3339 | 0.075 | -0.1776 | No |
| 4 | RFNG | RFNG Entrez, Source | radical fringe homolog (Drosophila) | 3363 | 0.074 | -0.1607 | No |
| 5 | HES1 | HES1 Entrez, Source | hairy and enhancer of split 1, (Drosophila) | 3410 | 0.073 | -0.1457 | No |
| 6 | DLL1 | DLL1 Entrez, Source | delta-like 1 (Drosophila) | 3523 | 0.070 | -0.1365 | No |
| 7 | PCAF | PCAF Entrez, Source | p300/CBP-associated factor | 4209 | 0.055 | -0.1742 | No |
| 8 | DVL1 | DVL1 Entrez, Source | dishevelled, dsh homolog 1 (Drosophila) | 4410 | 0.050 | -0.1767 | No |
| 9 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 5670 | 0.024 | -0.2652 | No |
| 10 | NOTCH4 | NOTCH4 Entrez, Source | Notch homolog 4 (Drosophila) | 5781 | 0.022 | -0.2678 | No |
| 11 | JAG2 | JAG2 Entrez, Source | jagged 2 | 6015 | 0.018 | -0.2808 | No |
| 12 | PSENEN | PSENEN Entrez, Source | presenilin enhancer 2 homolog (C. elegans) | 6105 | 0.016 | -0.2835 | No |
| 13 | PSEN1 | PSEN1 Entrez, Source | presenilin 1 (Alzheimer disease 3) | 6918 | -0.000 | -0.3444 | No |
| 14 | MFNG | MFNG Entrez, Source | manic fringe homolog (Drosophila) | 7360 | -0.010 | -0.3751 | No |
| 15 | LFNG | LFNG Entrez, Source | lunatic fringe homolog (Drosophila) | 8096 | -0.025 | -0.4240 | No |
| 16 | DTX4 | DTX4 Entrez, Source | deltex 4 homolog (Drosophila) | 8671 | -0.038 | -0.4575 | No |
| 17 | APH1A | APH1A Entrez, Source | anterior pharynx defective 1 homolog A (C. elegans) | 9742 | -0.066 | -0.5213 | No |
| 18 | CTBP1 | CTBP1 Entrez, Source | C-terminal binding protein 1 | 9803 | -0.068 | -0.5087 | No |
| 19 | NCSTN | NCSTN Entrez, Source | nicastrin | 9963 | -0.074 | -0.5022 | No |
| 20 | NUMBL | NUMBL Entrez, Source | numb homolog (Drosophila)-like | 10559 | -0.094 | -0.5234 | No |
| 21 | ADAM17 | ADAM17 Entrez, Source | ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme) | 11584 | -0.143 | -0.5646 | Yes |
| 22 | NUMB | NUMB Entrez, Source | numb homolog (Drosophila) | 11741 | -0.151 | -0.5384 | Yes |
| 23 | NOTCH1 | NOTCH1 Entrez, Source | Notch homolog 1, translocation-associated (Drosophila) | 12433 | -0.219 | -0.5354 | Yes |
| 24 | EP300 | EP300 Entrez, Source | E1A binding protein p300 | 12496 | -0.228 | -0.4829 | Yes |
| 25 | HDAC2 | HDAC2 Entrez, Source | histone deacetylase 2 | 12630 | -0.250 | -0.4303 | Yes |
| 26 | DTX2 | DTX2 Entrez, Source | deltex homolog 2 (Drosophila) | 12704 | -0.265 | -0.3694 | Yes |
| 27 | NOTCH2 | NOTCH2 Entrez, Source | Notch homolog 2 (Drosophila) | 12734 | -0.272 | -0.3033 | Yes |
| 28 | CTBP2 | CTBP2 Entrez, Source | C-terminal binding protein 2 | 13212 | -0.580 | -0.1938 | Yes |
| 29 | JAG1 | JAG1 Entrez, Source | jagged 1 (Alagille syndrome) | 13287 | -0.812 | 0.0041 | Yes |
