Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | HSA04512_ECM_RECEPTOR_INTERACTION |
| Enrichment Score (ES) | -0.51319045 |
| Normalized Enrichment Score (NES) | -1.645682 |
| Nominal p-value | 0.0059405942 |
| FDR q-value | 0.09897651 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | COL5A3 | COL5A3 Entrez, Source | collagen, type V, alpha 3 | 139 | 0.553 | 0.0521 | No |
| 2 | ITGA1 | ITGA1 Entrez, Source | integrin, alpha 1 | 278 | 0.416 | 0.0888 | No |
| 3 | VTN | VTN Entrez, Source | vitronectin | 766 | 0.225 | 0.0777 | No |
| 4 | SDC2 | SDC2 Entrez, Source | syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan) | 960 | 0.199 | 0.0856 | No |
| 5 | SV2B | SV2B Entrez, Source | synaptic vesicle glycoprotein 2B | 1251 | 0.167 | 0.0827 | No |
| 6 | LAMA3 | LAMA3 Entrez, Source | laminin, alpha 3 | 1875 | 0.127 | 0.0503 | No |
| 7 | COL6A2 | COL6A2 Entrez, Source | collagen, type VI, alpha 2 | 2097 | 0.118 | 0.0470 | No |
| 8 | COL11A1 | COL11A1 Entrez, Source | collagen, type XI, alpha 1 | 2613 | 0.099 | 0.0194 | No |
| 9 | SV2C | SV2C Entrez, Source | synaptic vesicle glycoprotein 2C | 3183 | 0.079 | -0.0144 | No |
| 10 | FNDC1 | FNDC1 Entrez, Source | fibronectin type III domain containing 1 | 3364 | 0.074 | -0.0196 | No |
| 11 | GP9 | GP9 Entrez, Source | glycoprotein IX (platelet) | 3635 | 0.068 | -0.0322 | No |
| 12 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 3806 | 0.064 | -0.0377 | No |
| 13 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 3998 | 0.059 | -0.0454 | No |
| 14 | DAG1 | DAG1 Entrez, Source | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 4171 | 0.056 | -0.0520 | No |
| 15 | ITGA7 | ITGA7 Entrez, Source | integrin, alpha 7 | 4309 | 0.053 | -0.0564 | No |
| 16 | VWF | VWF Entrez, Source | von Willebrand factor | 4369 | 0.051 | -0.0550 | No |
| 17 | COL2A1 | COL2A1 Entrez, Source | collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) | 4714 | 0.044 | -0.0760 | No |
| 18 | SDC4 | SDC4 Entrez, Source | syndecan 4 (amphiglycan, ryudocan) | 4826 | 0.041 | -0.0797 | No |
| 19 | TNR | TNR Entrez, Source | tenascin R (restrictin, janusin) | 5041 | 0.037 | -0.0915 | No |
| 20 | THBS4 | THBS4 Entrez, Source | thrombospondin 4 | 5218 | 0.034 | -0.1010 | No |
| 21 | IBSP | IBSP Entrez, Source | integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II) | 5397 | 0.030 | -0.1109 | No |
| 22 | COL5A1 | COL5A1 Entrez, Source | collagen, type V, alpha 1 | 5666 | 0.024 | -0.1284 | No |
| 23 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 6077 | 0.017 | -0.1573 | No |
| 24 | LAMB3 | LAMB3 Entrez, Source | laminin, beta 3 | 7303 | -0.008 | -0.2485 | No |
| 25 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 7328 | -0.009 | -0.2494 | No |
| 26 | COL4A4 | COL4A4 Entrez, Source | collagen, type IV, alpha 4 | 7382 | -0.010 | -0.2522 | No |
| 27 | GP5 | GP5 Entrez, Source | glycoprotein V (platelet) | 7405 | -0.010 | -0.2527 | No |
| 28 | SDC3 | SDC3 Entrez, Source | syndecan 3 (N-syndecan) | 7495 | -0.012 | -0.2580 | No |
| 29 | FNDC5 | FNDC5 Entrez, Source | fibronectin type III domain containing 5 | 8027 | -0.024 | -0.2953 | No |
| 30 | CHAD | CHAD Entrez, Source | chondroadherin | 8079 | -0.025 | -0.2963 | No |
| 31 | ITGB7 | ITGB7 Entrez, Source | integrin, beta 7 | 9605 | -0.063 | -0.4039 | No |
| 32 | SV2A | SV2A Entrez, Source | synaptic vesicle glycoprotein 2A | 9631 | -0.064 | -0.3986 | No |
| 33 | SDC1 | SDC1 Entrez, Source | syndecan 1 | 9762 | -0.067 | -0.4008 | No |
| 34 | FN1 | FN1 Entrez, Source | fibronectin 1 | 9917 | -0.072 | -0.4043 | No |
| 35 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 11366 | -0.129 | -0.4985 | Yes |
| 36 | CD47 | CD47 Entrez, Source | CD47 molecule | 11473 | -0.136 | -0.4912 | Yes |
| 37 | ITGB6 | ITGB6 Entrez, Source | integrin, beta 6 | 11573 | -0.142 | -0.4826 | Yes |
| 38 | ITGB4 | ITGB4 Entrez, Source | integrin, beta 4 | 11844 | -0.160 | -0.4848 | Yes |
| 39 | ITGA9 | ITGA9 Entrez, Source | integrin, alpha 9 | 12149 | -0.186 | -0.4866 | Yes |
| 40 | RELN | RELN Entrez, Source | reelin | 12369 | -0.211 | -0.4791 | Yes |
| 41 | HMMR | HMMR Entrez, Source | hyaluronan-mediated motility receptor (RHAMM) | 12560 | -0.237 | -0.4666 | Yes |
| 42 | LAMC2 | LAMC2 Entrez, Source | laminin, gamma 2 | 12640 | -0.252 | -0.4441 | Yes |
| 43 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 12719 | -0.269 | -0.4195 | Yes |
| 44 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 12760 | -0.277 | -0.3911 | Yes |
| 45 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 12818 | -0.293 | -0.3623 | Yes |
| 46 | LAMC1 | LAMC1 Entrez, Source | laminin, gamma 1 (formerly LAMB2) | 12835 | -0.298 | -0.3297 | Yes |
| 47 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 12902 | -0.323 | -0.2981 | Yes |
| 48 | LAMA5 | LAMA5 Entrez, Source | laminin, alpha 5 | 13171 | -0.510 | -0.2606 | Yes |
| 49 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 13233 | -0.633 | -0.1936 | Yes |
| 50 | COL4A1 | COL4A1 Entrez, Source | collagen, type IV, alpha 1 | 13269 | -0.760 | -0.1102 | Yes |
| 51 | LAMB2 | LAMB2 Entrez, Source | laminin, beta 2 (laminin S) | 13313 | -1.021 | 0.0022 | Yes |
