Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | HSA04520_ADHERENS_JUNCTION |
| Enrichment Score (ES) | -0.5398849 |
| Normalized Enrichment Score (NES) | -1.7167907 |
| Nominal p-value | 0.007490637 |
| FDR q-value | 0.0737357 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ACVR1C | ACVR1C Entrez, Source | activin A receptor, type IC | 641 | 0.255 | -0.0108 | No |
| 2 | LEF1 | LEF1 Entrez, Source | lymphoid enhancer-binding factor 1 | 815 | 0.219 | 0.0083 | No |
| 3 | FYN | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 1691 | 0.137 | -0.0374 | No |
| 4 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 2102 | 0.118 | -0.0510 | No |
| 5 | PTPN6 | PTPN6 Entrez, Source | protein tyrosine phosphatase, non-receptor type 6 | 2383 | 0.107 | -0.0564 | No |
| 6 | INSR | INSR Entrez, Source | insulin receptor | 2897 | 0.088 | -0.0821 | No |
| 7 | PTPRM | PTPRM Entrez, Source | protein tyrosine phosphatase, receptor type, M | 3619 | 0.068 | -0.1263 | No |
| 8 | SNAI1 | SNAI1 Entrez, Source | snail homolog 1 (Drosophila) | 3621 | 0.068 | -0.1164 | No |
| 9 | RAC2 | RAC2 Entrez, Source | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 3759 | 0.065 | -0.1172 | No |
| 10 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 4105 | 0.057 | -0.1348 | No |
| 11 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 5159 | 0.035 | -0.2089 | No |
| 12 | ACP1 | ACP1 Entrez, Source | acid phosphatase 1, soluble | 5200 | 0.034 | -0.2069 | No |
| 13 | CDH1 | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 5558 | 0.026 | -0.2299 | No |
| 14 | FGFR1 | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 6165 | 0.015 | -0.2733 | No |
| 15 | WASF2 | WASF2 Entrez, Source | WAS protein family, member 2 | 7261 | -0.008 | -0.3545 | No |
| 16 | CSNK2A1 | CSNK2A1 Entrez, Source | casein kinase 2, alpha 1 polypeptide | 7384 | -0.010 | -0.3622 | No |
| 17 | WASL | WASL Entrez, Source | Wiskott-Aldrich syndrome-like | 7397 | -0.010 | -0.3617 | No |
| 18 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 7461 | -0.012 | -0.3647 | No |
| 19 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 7490 | -0.012 | -0.3650 | No |
| 20 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 9133 | -0.050 | -0.4813 | No |
| 21 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 9885 | -0.071 | -0.5273 | No |
| 22 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 10053 | -0.076 | -0.5287 | Yes |
| 23 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 10171 | -0.080 | -0.5257 | Yes |
| 24 | PVRL2 | PVRL2 Entrez, Source | poliovirus receptor-related 2 (herpesvirus entry mediator B) | 10176 | -0.081 | -0.5142 | Yes |
| 25 | CSNK2B | CSNK2B Entrez, Source | casein kinase 2, beta polypeptide | 10221 | -0.082 | -0.5055 | Yes |
| 26 | SRC | SRC Entrez, Source | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 10292 | -0.084 | -0.4984 | Yes |
| 27 | CTNNB1 | CTNNB1 Entrez, Source | catenin (cadherin-associated protein), beta 1, 88kDa | 10376 | -0.087 | -0.4919 | Yes |
| 28 | ACTB | ACTB Entrez, Source | actin, beta | 10590 | -0.095 | -0.4940 | Yes |
| 29 | PTPN1 | PTPN1 Entrez, Source | protein tyrosine phosphatase, non-receptor type 1 | 11110 | -0.117 | -0.5158 | Yes |
| 30 | RHOA | RHOA Entrez, Source | ras homolog gene family, member A | 11190 | -0.121 | -0.5040 | Yes |
| 31 | SMAD2 | SMAD2 Entrez, Source | SMAD, mothers against DPP homolog 2 (Drosophila) | 11475 | -0.136 | -0.5055 | Yes |
| 32 | TGFBR2 | TGFBR2 Entrez, Source | transforming growth factor, beta receptor II (70/80kDa) | 11501 | -0.137 | -0.4873 | Yes |
| 33 | SMAD3 | SMAD3 Entrez, Source | SMAD, mothers against DPP homolog 3 (Drosophila) | 11527 | -0.139 | -0.4688 | Yes |
| 34 | BAIAP2 | BAIAP2 Entrez, Source | BAI1-associated protein 2 | 11565 | -0.141 | -0.4509 | Yes |
| 35 | SSX2IP | SSX2IP Entrez, Source | synovial sarcoma, X breakpoint 2 interacting protein | 11580 | -0.142 | -0.4311 | Yes |
| 36 | SMAD4 | SMAD4 Entrez, Source | SMAD, mothers against DPP homolog 4 (Drosophila) | 11978 | -0.171 | -0.4358 | Yes |
| 37 | PTPRF | PTPRF Entrez, Source | protein tyrosine phosphatase, receptor type, F | 12043 | -0.177 | -0.4147 | Yes |
| 38 | WASF1 | WASF1 Entrez, Source | WAS protein family, member 1 | 12111 | -0.182 | -0.3930 | Yes |
| 39 | ERBB2 | ERBB2 Entrez, Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 12237 | -0.197 | -0.3735 | Yes |
| 40 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 12269 | -0.201 | -0.3465 | Yes |
| 41 | EP300 | EP300 Entrez, Source | E1A binding protein p300 | 12496 | -0.228 | -0.3300 | Yes |
| 42 | TGFBR1 | TGFBR1 Entrez, Source | transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa) | 12538 | -0.234 | -0.2988 | Yes |
| 43 | MLLT4 | MLLT4 Entrez, Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | 12569 | -0.239 | -0.2661 | Yes |
| 44 | MET | MET Entrez, Source | met proto-oncogene (hepatocyte growth factor receptor) | 12926 | -0.331 | -0.2444 | Yes |
| 45 | PTPRJ | PTPRJ Entrez, Source | protein tyrosine phosphatase, receptor type, J | 13012 | -0.372 | -0.1963 | Yes |
| 46 | LMO7 | LMO7 Entrez, Source | LIM domain 7 | 13121 | -0.443 | -0.1395 | Yes |
| 47 | PARD3 | PARD3 Entrez, Source | par-3 partitioning defective 3 homolog (C. elegans) | 13124 | -0.445 | -0.0744 | Yes |
| 48 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13226 | -0.619 | 0.0087 | Yes |
