Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | HSA05219_BLADDER_CANCER |
| Enrichment Score (ES) | -0.58794385 |
| Normalized Enrichment Score (NES) | -1.6985948 |
| Nominal p-value | 0.011627907 |
| FDR q-value | 0.07818396 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DAPK2 | DAPK2 Entrez, Source | death-associated protein kinase 2 | 973 | 0.198 | -0.0351 | No |
| 2 | VEGFB | VEGFB Entrez, Source | vascular endothelial growth factor B | 1471 | 0.151 | -0.0435 | No |
| 3 | EGF | EGF Entrez, Source | epidermal growth factor (beta-urogastrone) | 1695 | 0.137 | -0.0339 | No |
| 4 | ARAF | ARAF Entrez, Source | v-raf murine sarcoma 3611 viral oncogene homolog | 1896 | 0.126 | -0.0247 | No |
| 5 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 2307 | 0.110 | -0.0344 | No |
| 6 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 2898 | 0.088 | -0.0618 | No |
| 7 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 3805 | 0.064 | -0.1176 | No |
| 8 | RAF1 | RAF1 Entrez, Source | v-raf-1 murine leukemia viral oncogene homolog 1 | 3847 | 0.063 | -0.1086 | No |
| 9 | BRAF | BRAF Entrez, Source | v-raf murine sarcoma viral oncogene homolog B1 | 5502 | 0.028 | -0.2275 | No |
| 10 | CDH1 | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 5558 | 0.026 | -0.2266 | No |
| 11 | FIGF | FIGF Entrez, Source | c-fos induced growth factor (vascular endothelial growth factor D) | 5779 | 0.022 | -0.2388 | No |
| 12 | VEGFC | VEGFC Entrez, Source | vascular endothelial growth factor C | 6727 | 0.004 | -0.3092 | No |
| 13 | MAP2K2 | MAP2K2 Entrez, Source | mitogen-activated protein kinase kinase 2 | 6934 | -0.001 | -0.3246 | No |
| 14 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 7490 | -0.012 | -0.3640 | No |
| 15 | DAPK3 | DAPK3 Entrez, Source | death-associated protein kinase 3 | 7689 | -0.016 | -0.3757 | No |
| 16 | KRAS | KRAS Entrez, Source | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 8009 | -0.024 | -0.3951 | No |
| 17 | PGF | PGF Entrez, Source | placental growth factor, vascular endothelial growth factor-related protein | 9515 | -0.060 | -0.4966 | No |
| 18 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 10053 | -0.076 | -0.5223 | No |
| 19 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 10171 | -0.080 | -0.5157 | No |
| 20 | RASSF1 | RASSF1 Entrez, Source | Ras association (RalGDS/AF-6) domain family 1 | 10613 | -0.096 | -0.5305 | No |
| 21 | MAP2K1 | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 11069 | -0.115 | -0.5426 | No |
| 22 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 11673 | -0.148 | -0.5595 | Yes |
| 23 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 11690 | -0.149 | -0.5321 | Yes |
| 24 | NRAS | NRAS Entrez, Source | neuroblastoma RAS viral (v-ras) oncogene homolog | 11999 | -0.173 | -0.5221 | Yes |
| 25 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 12039 | -0.176 | -0.4911 | Yes |
| 26 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 12163 | -0.188 | -0.4643 | Yes |
| 27 | ERBB2 | ERBB2 Entrez, Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 12237 | -0.197 | -0.4320 | Yes |
| 28 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 12794 | -0.284 | -0.4191 | Yes |
| 29 | FGFR3 | FGFR3 Entrez, Source | fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) | 13098 | -0.424 | -0.3605 | Yes |
| 30 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 13099 | -0.425 | -0.2790 | Yes |
| 31 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13162 | -0.500 | -0.1877 | Yes |
| 32 | MMP2 | MMP2 Entrez, Source | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 13316 | -1.048 | 0.0020 | Yes |
