Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_single_gel_8d.class.cls
#double_gel_8d_versus_single_gel_8d_repos
Phenotypeclass.cls#double_gel_8d_versus_single_gel_8d_repos
Upregulated in classdouble_gel_8d
GeneSetHUMAN_MITODB_6_2002
Enrichment Score (ES)0.51399
Normalized Enrichment Score (NES)2.183985
Nominal p-value0.0
FDR q-value8.420639E-5
FWER p-Value0.0040
Table: GSEA Results Summary



Fig 1: Enrichment plot: HUMAN_MITODB_6_2002   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1GLYATGLYAT
Entrez,  Source
glycine-N-acyltransferase101.1210.0302Yes
2OTCOTC
Entrez,  Source
ornithine carbamoyltransferase490.7650.0485Yes
3BCL2A1BCL2A1
Entrez,  Source
BCL2-related protein A1530.7400.0687Yes
4GOT1GOT1
Entrez,  Source
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)560.7310.0888Yes
5PDK4PDK4
Entrez,  Source
pyruvate dehydrogenase kinase, isozyme 4580.7260.1088Yes
6PCPC
Entrez,  Source
pyruvate carboxylase790.6520.1253Yes
7CPS1CPS1
Entrez,  Source
carbamoyl-phosphate synthetase 1, mitochondrial910.6310.1419Yes
8AGXTAGXT
Entrez,  Source
alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase)1080.6060.1575Yes
9SLC25A15SLC25A15
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 151130.5970.1737Yes
10GPTGPT
Entrez,  Source
glutamic-pyruvate transaminase (alanine aminotransferase)1370.5550.1873Yes
11PDK1PDK1
Entrez,  Source
pyruvate dehydrogenase kinase, isozyme 11430.5450.2020Yes
12TATTAT
Entrez,  Source
tyrosine aminotransferase2210.4570.2087Yes
13SARDHSARDH
Entrez,  Source
sarcosine dehydrogenase2450.4380.2191Yes
14GCKGCK
Entrez,  Source
glucokinase (hexokinase 4, maturity onset diabetes of the young 2)2590.4270.2299Yes
15ECHS1ECHS1
Entrez,  Source
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial2600.4270.2417Yes
16BCKDHBBCKDHB
Entrez,  Source
branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease)2710.4190.2525Yes
17CPT2CPT2
Entrez,  Source
carnitine palmitoyltransferase II2920.4020.2621Yes
18HSD3B1HSD3B1
Entrez,  Source
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 12930.4020.2732Yes
19HMGCLHMGCL
Entrez,  Source
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria)3440.3710.2796Yes
20BNIP3BNIP3
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 33560.3600.2887Yes
21HMGCS2HMGCS2
Entrez,  Source
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)3600.3580.2984Yes
22ETFDHETFDH
Entrez,  Source
electron-transferring-flavoprotein dehydrogenase3630.3570.3081Yes
23ACAA2ACAA2
Entrez,  Source
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)3740.3530.3171Yes
24BCKDHABCKDHA
Entrez,  Source
branched chain keto acid dehydrogenase E1, alpha polypeptide3890.3440.3256Yes
25SOD2SOD2
Entrez,  Source
superoxide dismutase 2, mitochondrial3910.3430.3350Yes
26TIMM8ATIMM8A
Entrez,  Source
translocase of inner mitochondrial membrane 8 homolog A (yeast)4120.3360.3427Yes
27ACAT1ACAT1
Entrez,  Source
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)4300.3290.3506Yes
28ABATABAT
Entrez,  Source
4-aminobutyrate aminotransferase4500.3200.3580Yes
29AMACRAMACR
Entrez,  Source
alpha-methylacyl-CoA racemase5330.2890.3597Yes
30ACADVLACADVL
Entrez,  Source
acyl-Coenzyme A dehydrogenase, very long chain5370.2880.3674Yes
31CYP27A1CYP27A1
Entrez,  Source
cytochrome P450, family 27, subfamily A, polypeptide 15780.2740.3720Yes
32SCP2SCP2
Entrez,  Source
sterol carrier protein 26240.2600.3757Yes
33SLC25A10SLC25A10
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 106420.2550.3815Yes
34DCIDCI
Entrez,  Source
dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase)6600.2500.3871Yes
35SLC25A20SLC25A20
Entrez,  Source
solute carrier family 25 (carnitine/acylcarnitine translocase), member 207590.2260.3859Yes
36GCATGCAT
Entrez,  Source
glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase)7670.2250.3915Yes
37PPIFPPIF
Entrez,  Source
peptidylprolyl isomerase F (cyclophilin F)7690.2240.3977Yes
38CLPXCLPX
Entrez,  Source
ClpX caseinolytic peptidase X homolog (E. coli)7850.2210.4026Yes
39DBTDBT
Entrez,  Source
dihydrolipoamide branched chain transacylase E27990.2200.4077Yes
40TIMM9TIMM9
Entrez,  Source
translocase of inner mitochondrial membrane 9 homolog (yeast)8280.2160.4116Yes
41ALAS1ALAS1
Entrez,  Source
aminolevulinate, delta-, synthase 18390.2150.4168Yes
42MCCC1MCCC1
Entrez,  Source
methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)8560.2130.4214Yes
43PDHBPDHB
Entrez,  Source
pyruvate dehydrogenase (lipoamide) beta8580.2130.4273Yes
44ETFBETFB
Entrez,  Source
electron-transfer-flavoprotein, beta polypeptide8650.2120.4327Yes
45ATP5G1ATP5G1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)8780.2100.4376Yes
46AK2AK2
Entrez,  Source
adenylate kinase 28800.2100.4433Yes
47TSTTST
Entrez,  Source
thiosulfate sulfurtransferase (rhodanese)9260.2030.4455Yes
48SLC25A1SLC25A1
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 19460.2000.4495Yes
49CPT1ACPT1A
Entrez,  Source
carnitine palmitoyltransferase 1A (liver)9500.2000.4548Yes
50TXN2TXN2
Entrez,  Source
thioredoxin 210190.1900.4549Yes
51MTHFD1MTHFD1
Entrez,  Source
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase10500.1870.4578Yes
52SHMT2SHMT2
Entrez,  Source
serine hydroxymethyltransferase 2 (mitochondrial)11050.1810.4587Yes
53ACADSBACADSB
Entrez,  Source
acyl-Coenzyme A dehydrogenase, short/branched chain11580.1750.4596Yes
54NDUFV2NDUFV2
Entrez,  Source
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa11610.1750.4642Yes
55ODC1ODC1
Entrez,  Source
ornithine decarboxylase 112050.1700.4657Yes
56SDSSDS
Entrez,  Source
serine dehydratase12220.1690.4691Yes
57PRDX3PRDX3
Entrez,  Source
peroxiredoxin 312740.1660.4698Yes
58CPT1BCPT1B
Entrez,  Source
carnitine palmitoyltransferase 1B (muscle)12780.1650.4741Yes
59POLGPOLG
Entrez,  Source
polymerase (DNA directed), gamma12880.1650.4780Yes
60ACADSACADS
Entrez,  Source
acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain12960.1640.4820Yes
61DECR1DECR1
Entrez,  Source
2,4-dienoyl CoA reductase 1, mitochondrial13150.1630.4851Yes
62HADHAHADHA
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit13990.1570.4831Yes
63SDHDSDHD
Entrez,  Source
succinate dehydrogenase complex, subunit D, integral membrane protein14040.1570.4872Yes
64AFG3L2AFG3L2
Entrez,  Source
AFG3 ATPase family gene 3-like 2 (yeast)14490.1530.4880Yes
65OATOAT
Entrez,  Source
ornithine aminotransferase (gyrate atrophy)14600.1520.4915Yes
66COQ7COQ7
Entrez,  Source
coenzyme Q7 homolog, ubiquinone (yeast)14760.1510.4945Yes
67TIMM10TIMM10
Entrez,  Source
translocase of inner mitochondrial membrane 10 homolog (yeast)14910.1500.4976Yes
68PCCBPCCB
Entrez,  Source
propionyl Coenzyme A carboxylase, beta polypeptide16200.1420.4918Yes
69DLDDLD
Entrez,  Source
dihydrolipoamide dehydrogenase16280.1410.4951Yes
70MAOBMAOB
Entrez,  Source
monoamine oxidase B17120.1370.4926Yes
71HADHBHADHB
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit17470.1340.4937Yes
72SPG7SPG7
Entrez,  Source
spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive)17920.1320.4940Yes
73SLC25A21SLC25A21
Entrez,  Source
solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 2118040.1310.4967Yes
74UROSUROS
Entrez,  Source
uroporphyrinogen III synthase (congenital erythropoietic porphyria)18420.1290.4975Yes
75COX7BCOX7B
Entrez,  Source
cytochrome c oxidase subunit VIIb18490.1290.5006Yes
76GLUD1GLUD1
Entrez,  Source
glutamate dehydrogenase 118640.1280.5031Yes
77UQCRBUQCRB
Entrez,  Source
ubiquinol-cytochrome c reductase binding protein18800.1270.5054Yes
78SHMT1SHMT1
Entrez,  Source
serine hydroxymethyltransferase 1 (soluble)18920.1270.5081Yes
79MRPL12MRPL12
Entrez,  Source
mitochondrial ribosomal protein L1219400.1240.5079Yes
80MIPEPMIPEP
Entrez,  Source
mitochondrial intermediate peptidase19640.1230.5096Yes
81ACADLACADL
Entrez,  Source
acyl-Coenzyme A dehydrogenase, long chain20240.1210.5084Yes
82ENDOGENDOG
Entrez,  Source
endonuclease G20360.1200.5109Yes
83MRPL46MRPL46
Entrez,  Source
mitochondrial ribosomal protein L4620400.1200.5140Yes
84MRPL16MRPL16
Entrez,  Source
mitochondrial ribosomal protein L1621320.1170.5103No
85NFS1NFS1
Entrez,  Source
NFS1 nitrogen fixation 1 (S. cerevisiae)21830.1150.5096No
86TXNRD2TXNRD2
Entrez,  Source
thioredoxin reductase 222000.1140.5116No
87IVDIVD
Entrez,  Source
isovaleryl Coenzyme A dehydrogenase22480.1130.5111No
88BCS1LBCS1L
Entrez,  Source
BCS1-like (yeast)22720.1110.5124No
89ATP5EATP5E
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit23240.1090.5115No
90ATP5OATP5O
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein)24500.1050.5049No
91BCL2BCL2
Entrez,  Source
B-cell CLL/lymphoma 224670.1040.5065No
92TFB1MTFB1M
Entrez,  Source
transcription factor B1, mitochondrial25800.1000.5008No
93TIMM8BTIMM8B
Entrez,  Source
translocase of inner mitochondrial membrane 8 homolog B (yeast)25920.1000.5027No
94ETFAETFA
Entrez,  Source
electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II)26500.0980.5010No
95NDUFS7NDUFS7
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)26740.0960.5019No
96STARSTAR
Entrez,  Source
steroidogenic acute regulator26760.0960.5045No
97OGG1OGG1
Entrez,  Source
8-oxoguanine DNA glycosylase26770.0960.5072No
98DHODHDHODH
Entrez,  Source
dihydroorotate dehydrogenase27520.0940.5041No
99SLC25A5SLC25A5
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 527560.0940.5065No
100GPD2GPD2
Entrez,  Source
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)27710.0930.5080No
101MAOAMAOA
Entrez,  Source
monoamine oxidase A28020.0910.5082No
102SDHASDHA
Entrez,  Source
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)28860.0880.5043No
103ATP7BATP7B
Entrez,  Source
ATPase, Cu++ transporting, beta polypeptide29000.0880.5057No
104NDUFS2NDUFS2
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)29260.0870.5063No
105PDCD8PDCD8
Entrez,  Source
programmed cell death 8 (apoptosis-inducing factor)30030.0850.5028No
106ATP5G3ATP5G3
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)30380.0840.5025No
107TOMM70ATOMM70A
Entrez,  Source
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)30620.0830.5030No
108BCKDKBCKDK
Entrez,  Source
branched chain ketoacid dehydrogenase kinase30820.0820.5039No
109SURF1SURF1
Entrez,  Source
surfeit 130980.0820.5050No
110HSPE1HSPE1
Entrez,  Source
heat shock 10kDa protein 1 (chaperonin 10)32270.0780.4974No
111ARG2ARG2
Entrez,  Source
arginase, type II34490.0720.4825No
112MRPS15MRPS15
Entrez,  Source
mitochondrial ribosomal protein S1534960.0710.4809No
113COX6A2COX6A2
Entrez,  Source
cytochrome c oxidase subunit VIa polypeptide 235170.0710.4813No
114IDH3BIDH3B
Entrez,  Source
isocitrate dehydrogenase 3 (NAD+) beta35450.0700.4812No
115COX7A2COX7A2
Entrez,  Source
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)36470.0680.4754No
116GATMGATM
Entrez,  Source
glycine amidinotransferase (L-arginine:glycine amidinotransferase)36910.0670.4739No
117ATP5JATP5J
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F637090.0660.4745No
118ATP5G2ATP5G2
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)37310.0660.4747No
119MRPS7MRPS7
Entrez,  Source
mitochondrial ribosomal protein S737450.0650.4755No
120RAF1RAF1
Entrez,  Source
v-raf-1 murine leukemia viral oncogene homolog 138470.0630.4695No
121AMTAMT
Entrez,  Source
aminomethyltransferase38750.0630.4692No
122ATP5F1ATP5F1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B138860.0620.4701No
123SDHCSDHC
Entrez,  Source
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa38980.0620.4710No
124NDUFC2NDUFC2
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa39090.0620.4720No
125ABCB6ABCB6
Entrez,  Source
ATP-binding cassette, sub-family B (MDR/TAP), member 639580.0610.4700No
126ATP5IATP5I
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E39630.0610.4713No
127PRSS15PRSS15
Entrez,  Source
protease, serine, 1539900.0600.4710No
128BNIP3LBNIP3L
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 3-like40110.0590.4711No
129GSRGSR
Entrez,  Source
glutathione reductase40180.0590.4723No
130UQCRFS1UQCRFS1
Entrez,  Source
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 140240.0590.4735No
131UCP1UCP1
Entrez,  Source
uncoupling protein 1 (mitochondrial, proton carrier)41330.0560.4668No
132UQCRC2UQCRC2
Entrez,  Source
ubiquinol-cytochrome c reductase core protein II41410.0560.4678No
133MDH2MDH2
Entrez,  Source
malate dehydrogenase 2, NAD (mitochondrial)41680.0560.4674No
134GRID2GRID2
Entrez,  Source
glutamate receptor, ionotropic, delta 242380.0540.4636No
135ATP5C1ATP5C1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 142830.0530.4617No
136ACADMACADM
Entrez,  Source
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain43100.0530.4612No
137COX5BCOX5B
Entrez,  Source
cytochrome c oxidase subunit Vb43250.0520.4616No
138ACO2ACO2
Entrez,  Source
aconitase 2, mitochondrial43530.0520.4609No
139NDUFS6NDUFS6
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)43550.0510.4623No
140COX6CCOX6C
Entrez,  Source
cytochrome c oxidase subunit VIc44410.0500.4572No
141MRPL11MRPL11
Entrez,  Source
mitochondrial ribosomal protein L1144850.0490.4552No
142MRPL44MRPL44
Entrez,  Source
mitochondrial ribosomal protein L4445140.0480.4544No
143DAP3DAP3
Entrez,  Source
death associated protein 345900.0470.4500No
144MPSTMPST
Entrez,  Source
mercaptopyruvate sulfurtransferase47130.0440.4419No
145PDHA1PDHA1
Entrez,  Source
pyruvate dehydrogenase (lipoamide) alpha 147720.0420.4386No
146NR3C1NR3C1
Entrez,  Source
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)47910.0420.4384No
147ACP6ACP6
Entrez,  Source
acid phosphatase 6, lysophosphatidic48170.0420.4376No
148UQCRC1UQCRC1
Entrez,  Source
ubiquinol-cytochrome c reductase core protein I48610.0410.4355No
149DLSTDLST
Entrez,  Source
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)48840.0400.4349No
150UQCRHUQCRH
Entrez,  Source
ubiquinol-cytochrome c reductase hinge protein49660.0390.4298No
151BLVRABLVRA
Entrez,  Source
biliverdin reductase A49730.0380.4304No
152OPA1OPA1
Entrez,  Source
optic atrophy 1 (autosomal dominant)50050.0380.4290No
153ATP5DATP5D
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit50130.0380.4296No
154AK3AK3
Entrez,  Source
adenylate kinase 350820.0360.4254No
155CYP27B1CYP27B1
Entrez,  Source
cytochrome P450, family 27, subfamily B, polypeptide 152480.0330.4137No
156MRPL34MRPL34
Entrez,  Source
mitochondrial ribosomal protein L3452520.0330.4143No
157SUCLG1SUCLG1
Entrez,  Source
succinate-CoA ligase, GDP-forming, alpha subunit52600.0330.4147No
158CYCSCYCS
Entrez,  Source
cytochrome c, somatic53200.0320.4111No
159SLC1A3SLC1A3
Entrez,  Source
solute carrier family 1 (glial high affinity glutamate transporter), member 353620.0310.4088No
160COX4I1COX4I1
Entrez,  Source
cytochrome c oxidase subunit IV isoform 153800.0310.4083No
161NDUFS1NDUFS1
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)53950.0300.4081No
162MRPL19MRPL19
Entrez,  Source
mitochondrial ribosomal protein L1956940.0240.3860No
163CRATCRAT
Entrez,  Source
carnitine acetyltransferase57160.0230.3850No
164MRPL17MRPL17
Entrez,  Source
mitochondrial ribosomal protein L1757200.0230.3855No
165BCL2L11BCL2L11
Entrez,  Source
BCL2-like 11 (apoptosis facilitator)57240.0230.3859No
166ATP5BATP5B
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide57770.0220.3825No
167COX5ACOX5A
Entrez,  Source
cytochrome c oxidase subunit Va58000.0220.3814No
168SUPV3L1SUPV3L1
Entrez,  Source
suppressor of var1, 3-like 1 (S. cerevisiae)58020.0220.3820No
169HCLS1HCLS1
Entrez,  Source
hematopoietic cell-specific Lyn substrate 160430.0170.3641No
170ALDH2ALDH2
Entrez,  Source
aldehyde dehydrogenase 2 family (mitochondrial)62790.0120.3465No
171MRPS18BMRPS18B
Entrez,  Source
mitochondrial ribosomal protein S18B62920.0120.3459No
172MRPL9MRPL9
Entrez,  Source
mitochondrial ribosomal protein L963140.0120.3446No
173TRAP1TRAP1
Entrez,  Source
TNF receptor-associated protein 163350.0110.3434No
174CRY1CRY1
Entrez,  Source
cryptochrome 1 (photolyase-like)63560.0100.3422No
175PMPCBPMPCB
Entrez,  Source
peptidase (mitochondrial processing) beta64060.0090.3387No
176IDH3AIDH3A
Entrez,  Source
isocitrate dehydrogenase 3 (NAD+) alpha64330.0090.3370No
177DIABLODIABLO
Entrez,  Source
diablo homolog (Drosophila)64490.0090.3361No
178NDUFS4NDUFS4
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)64770.0080.3342No
179NDUFA5NDUFA5
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa65530.0070.3287No
180TOMM40TOMM40
Entrez,  Source
translocase of outer mitochondrial membrane 40 homolog (yeast)65980.0060.3255No
181NDUFA9NDUFA9
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa66650.0050.3206No
182CLN3CLN3
Entrez,  Source
ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)66860.0040.3192No
183NDUFB4NDUFB4
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa66900.0040.3191No
184MTIF2MTIF2
Entrez,  Source
mitochondrial translational initiation factor 267120.0040.3176No
185GPX4GPX4
Entrez,  Source
glutathione peroxidase 4 (phospholipid hydroperoxidase)67210.0040.3171No
186HSPD1HSPD1
Entrez,  Source
heat shock 60kDa protein 1 (chaperonin)67720.0030.3133No
187ABCB8ABCB8
Entrez,  Source
ATP-binding cassette, sub-family B (MDR/TAP), member 867730.0030.3134No
188MRPL13MRPL13
Entrez,  Source
mitochondrial ribosomal protein L1368220.0020.3098No
189COX6A1COX6A1
Entrez,  Source
cytochrome c oxidase subunit VIa polypeptide 168670.0010.3064No
190IMMTIMMT
Entrez,  Source
inner membrane protein, mitochondrial (mitofilin)68760.0010.3059No
191VDAC3VDAC3
Entrez,  Source
voltage-dependent anion channel 37025-0.0030.2946No
192SSBP1SSBP1
Entrez,  Source
single-stranded DNA binding protein 17057-0.0030.2923No
193TOMM20TOMM20
Entrez,  Source
translocase of outer mitochondrial membrane 20 homolog (yeast)7072-0.0040.2914No
194MRPS18AMRPS18A
Entrez,  Source
mitochondrial ribosomal protein S18A7193-0.0060.2824No
195MFN2MFN2
Entrez,  Source
mitofusin 27196-0.0060.2824No
196GOT2GOT2
Entrez,  Source
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)7234-0.0070.2798No
197NDUFA8NDUFA8
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa7295-0.0080.2754No
198MRPL2MRPL2
Entrez,  Source
mitochondrial ribosomal protein L27336-0.0090.2726No
199DNM1LDNM1L
Entrez,  Source
dynamin 1-like7354-0.0090.2715No
200MTERFMTERF
Entrez,  Source
mitochondrial transcription termination factor7400-0.0100.2684No
201TIMM44TIMM44
Entrez,  Source
translocase of inner mitochondrial membrane 44 homolog (yeast)7409-0.0100.2681No
202MRPL24MRPL24
Entrez,  Source
mitochondrial ribosomal protein L247475-0.0120.2634No
203CSCS
Entrez,  Source
citrate synthase7513-0.0130.2609No
204ATP5HATP5H
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d7543-0.0130.2591No
205LYPLA2LYPLA2
Entrez,  Source
lysophospholipase II7583-0.0140.2565No
206CYP11B1CYP11B1
Entrez,  Source
cytochrome P450, family 11, subfamily B, polypeptide 17700-0.0170.2481No
207TFAMTFAM
Entrez,  Source
transcription factor A, mitochondrial7833-0.0190.2386No
208FDXRFDXR
Entrez,  Source
ferredoxin reductase7908-0.0210.2335No
209SLC1A1SLC1A1
Entrez,  Source
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 18024-0.0240.2254No
210TIMM13TIMM13
Entrez,  Source
translocase of inner mitochondrial membrane 13 homolog (yeast)8076-0.0250.2222No
211AKAP1AKAP1
Entrez,  Source
A kinase (PRKA) anchor protein 18091-0.0250.2218No
212RPL3RPL3
Entrez,  Source
ribosomal protein L38109-0.0260.2212No
213TIMM17ATIMM17A
Entrez,  Source
translocase of inner mitochondrial membrane 17 homolog A (yeast)8212-0.0280.2142No
214BCAT2BCAT2
Entrez,  Source
branched chain aminotransferase 2, mitochondrial8232-0.0280.2135No
215GALR3GALR3
Entrez,  Source
galanin receptor 38247-0.0290.2132No
216VDAC2VDAC2
Entrez,  Source
voltage-dependent anion channel 28404-0.0320.2022No
217CYBBCYBB
Entrez,  Source
cytochrome b-245, beta polypeptide (chronic granulomatous disease)8513-0.0350.1949No
218RPS3ARPS3A
Entrez,  Source
ribosomal protein S3A8514-0.0350.1959No
219BCL2L1BCL2L1
Entrez,  Source
BCL2-like 18585-0.0370.1915No
220IDH3GIDH3G
Entrez,  Source
isocitrate dehydrogenase 3 (NAD+) gamma8587-0.0370.1925No
221CA5BCA5B
Entrez,  Source
carbonic anhydrase VB, mitochondrial8760-0.0400.1804No
222SLC25A11SLC25A11
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 118929-0.0440.1688No
223TOMM22TOMM22
Entrez,  Source
translocase of outer mitochondrial membrane 22 homolog (yeast)9085-0.0480.1583No
224UCP3UCP3
Entrez,  Source
uncoupling protein 3 (mitochondrial, proton carrier)9230-0.0520.1488No
225TIMM22TIMM22
Entrez,  Source
translocase of inner mitochondrial membrane 22 homolog (yeast)9516-0.0600.1286No
226MUTYHMUTYH
Entrez,  Source
mutY homolog (E. coli)9600-0.0630.1240No
227PPM2CPPM2C
Entrez,  Source
protein phosphatase 2C, magnesium-dependent, catalytic subunit9971-0.0740.0978No
228SLC25A3SLC25A3
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 310075-0.0770.0921No
229BIDBID
Entrez,  Source
BH3 interacting domain death agonist10406-0.0880.0693No
230SLC25A4SLC25A4
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 410578-0.0940.0588No
231BAXBAX
Entrez,  Source
BCL2-associated X protein10699-0.0980.0524No
232MRPL49MRPL49
Entrez,  Source
mitochondrial ribosomal protein L4910732-0.1000.0527No
233ATPIF1ATPIF1
Entrez,  Source
ATPase inhibitory factor 110815-0.1030.0493No
234FDX1FDX1
Entrez,  Source
ferredoxin 110969-0.1100.0406No
235ATP5SATP5S
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B)11182-0.1200.0278No
236PPIDPPID
Entrez,  Source
peptidylprolyl isomerase D (cyclophilin D)11332-0.1280.0199No
237FIBPFIBP
Entrez,  Source
fibroblast growth factor (acidic) intracellular binding protein11371-0.1300.0206No
238DUTDUT
Entrez,  Source
dUTP pyrophosphatase11400-0.1310.0221No
239CASP8CASP8
Entrez,  Source
caspase 8, apoptosis-related cysteine peptidase11401-0.1310.0257No
240DNASE2DNASE2
Entrez,  Source
deoxyribonuclease II, lysosomal11563-0.1410.0173No
241CYP11A1CYP11A1
Entrez,  Source
cytochrome P450, family 11, subfamily A, polypeptide 111705-0.1500.0107No
242DLATDLAT
Entrez,  Source
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)11723-0.1500.0135No
243BADBAD
Entrez,  Source
BCL2-antagonist of cell death11752-0.1520.0156No
244FRAP1FRAP1
Entrez,  Source
FK506 binding protein 12-rapamycin associated protein 111775-0.1550.0182No
245MTCH1MTCH1
Entrez,  Source
mitochondrial carrier homolog 1 (C. elegans)11859-0.1610.0163No
246BAK1BAK1
Entrez,  Source
BCL2-antagonist/killer 112372-0.212-0.0169No
247CA5ACA5A
Entrez,  Source
carbonic anhydrase VA, mitochondrial12440-0.220-0.0160No
248APAF1APAF1
Entrez,  Source
apoptotic peptidase activating factor12510-0.230-0.0149No
249POPDC2POPDC2
Entrez,  Source
popeye domain containing 212600-0.245-0.0149No
250HK1HK1
Entrez,  Source
hexokinase 112636-0.251-0.0106No
251COX15COX15
Entrez,  Source
COX15 homolog, cytochrome c oxidase assembly protein (yeast)12707-0.266-0.0086No
252CYBACYBA
Entrez,  Source
cytochrome b-245, alpha polypeptide12989-0.359-0.0202No
253GLSGLS
Entrez,  Source
glutaminase13118-0.442-0.0177No
254NGFRAP1NGFRAP1
Entrez,  Source
nerve growth factor receptor (TNFRSF16) associated protein 113127-0.447-0.0060No
255UCP2UCP2
Entrez,  Source
uncoupling protein 2 (mitochondrial, proton carrier)13284-0.8080.0044No
Table: GSEA details [plain text format]



Fig 2: HUMAN_MITODB_6_2002   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: HUMAN_MITODB_6_2002: Random ES distribution   
Gene set null distribution of ES for HUMAN_MITODB_6_2002