Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | IDX_TSA_DN_CLUSTER3 |
| Enrichment Score (ES) | -0.56661814 |
| Normalized Enrichment Score (NES) | -1.8754488 |
| Nominal p-value | 0.0019120459 |
| FDR q-value | 0.02636751 |
| FWER p-Value | 0.592 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PHLDA1 | PHLDA1 Entrez, Source | pleckstrin homology-like domain, family A, member 1 | 303 | 0.396 | 0.0105 | No |
| 2 | FADS1 | FADS1 Entrez, Source | fatty acid desaturase 1 | 401 | 0.338 | 0.0317 | No |
| 3 | CXCL12 | CXCL12 Entrez, Source | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | 407 | 0.337 | 0.0597 | No |
| 4 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 1016 | 0.190 | 0.0300 | No |
| 5 | GSTT1 | GSTT1 Entrez, Source | glutathione S-transferase theta 1 | 1394 | 0.157 | 0.0148 | No |
| 6 | GPC4 | GPC4 Entrez, Source | glypican 4 | 2133 | 0.117 | -0.0309 | No |
| 7 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 2379 | 0.107 | -0.0403 | No |
| 8 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 2802 | 0.091 | -0.0643 | No |
| 9 | GGTA1 | GGTA1 Entrez, Source | glycoprotein, alpha-galactosyltransferase 1 | 3574 | 0.069 | -0.1165 | No |
| 10 | CSF1 | CSF1 Entrez, Source | colony stimulating factor 1 (macrophage) | 3716 | 0.066 | -0.1216 | No |
| 11 | TSPYL4 | TSPYL4 Entrez, Source | TSPY-like 4 | 3740 | 0.065 | -0.1178 | No |
| 12 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 3806 | 0.064 | -0.1173 | No |
| 13 | PLK2 | PLK2 Entrez, Source | polo-like kinase 2 (Drosophila) | 4002 | 0.059 | -0.1270 | No |
| 14 | CEBPD | CEBPD Entrez, Source | CCAAT/enhancer binding protein (C/EBP), delta | 4687 | 0.044 | -0.1748 | No |
| 15 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 5084 | 0.036 | -0.2015 | No |
| 16 | ACVR2A | ACVR2A Entrez, Source | activin A receptor, type IIA | 5863 | 0.021 | -0.2583 | No |
| 17 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 6077 | 0.017 | -0.2729 | No |
| 18 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 7004 | -0.002 | -0.3425 | No |
| 19 | SFRP2 | SFRP2 Entrez, Source | secreted frizzled-related protein 2 | 7256 | -0.008 | -0.3607 | No |
| 20 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 7589 | -0.014 | -0.3845 | No |
| 21 | DNM1 | DNM1 Entrez, Source | dynamin 1 | 7697 | -0.017 | -0.3912 | No |
| 22 | PRKCD | PRKCD Entrez, Source | protein kinase C, delta | 8690 | -0.039 | -0.4626 | No |
| 23 | SKAP2 | SKAP2 Entrez, Source | src kinase associated phosphoprotein 2 | 9093 | -0.049 | -0.4887 | No |
| 24 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 9477 | -0.059 | -0.5126 | No |
| 25 | SLC8A1 | SLC8A1 Entrez, Source | solute carrier family 8 (sodium/calcium exchanger), member 1 | 9583 | -0.062 | -0.5153 | No |
| 26 | EPHX1 | EPHX1 Entrez, Source | epoxide hydrolase 1, microsomal (xenobiotic) | 9718 | -0.066 | -0.5198 | No |
| 27 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 10193 | -0.081 | -0.5487 | No |
| 28 | ANXA11 | ANXA11 Entrez, Source | annexin A11 | 10207 | -0.082 | -0.5428 | No |
| 29 | STXBP3 | STXBP3 Entrez, Source | syntaxin binding protein 3 | 10258 | -0.083 | -0.5395 | No |
| 30 | SIRT2 | SIRT2 Entrez, Source | sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) | 10295 | -0.085 | -0.5351 | No |
| 31 | RASSF5 | RASSF5 Entrez, Source | Ras association (RalGDS/AF-6) domain family 5 | 10560 | -0.094 | -0.5471 | No |
| 32 | PTGS2 | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 10604 | -0.095 | -0.5423 | No |
| 33 | CCT3 | CCT3 Entrez, Source | chaperonin containing TCP1, subunit 3 (gamma) | 10769 | -0.102 | -0.5461 | No |
| 34 | CSRP1 | CSRP1 Entrez, Source | cysteine and glycine-rich protein 1 | 10850 | -0.105 | -0.5433 | No |
| 35 | PLEKHC1 | PLEKHC1 Entrez, Source | pleckstrin homology domain containing, family C (with FERM domain) member 1 | 11076 | -0.115 | -0.5505 | No |
| 36 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 11087 | -0.116 | -0.5415 | No |
| 37 | BCAR1 | BCAR1 Entrez, Source | breast cancer anti-estrogen resistance 1 | 11123 | -0.118 | -0.5342 | No |
| 38 | CNN3 | CNN3 Entrez, Source | calponin 3, acidic | 11257 | -0.124 | -0.5337 | No |
| 39 | NEDD9 | NEDD9 Entrez, Source | neural precursor cell expressed, developmentally down-regulated 9 | 11695 | -0.149 | -0.5540 | Yes |
| 40 | SPG20 | SPG20 Entrez, Source | spastic paraplegia 20, spartin (Troyer syndrome) | 11730 | -0.151 | -0.5439 | Yes |
| 41 | EXOC4 | EXOC4 Entrez, Source | exocyst complex component 4 | 11967 | -0.170 | -0.5473 | Yes |
| 42 | ROCK2 | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 12156 | -0.187 | -0.5457 | Yes |
| 43 | MAGED2 | MAGED2 Entrez, Source | melanoma antigen family D, 2 | 12245 | -0.198 | -0.5356 | Yes |
| 44 | JUP | JUP Entrez, Source | junction plakoglobin | 12351 | -0.210 | -0.5258 | Yes |
| 45 | PSCD3 | PSCD3 Entrez, Source | pleckstrin homology, Sec7 and coiled-coil domains 3 | 12426 | -0.218 | -0.5130 | Yes |
| 46 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 12794 | -0.284 | -0.5167 | Yes |
| 47 | FZD2 | FZD2 Entrez, Source | frizzled homolog 2 (Drosophila) | 12935 | -0.334 | -0.4991 | Yes |
| 48 | NDRG4 | NDRG4 Entrez, Source | NDRG family member 4 | 12943 | -0.337 | -0.4712 | Yes |
| 49 | PLA2G4A | PLA2G4A Entrez, Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 12946 | -0.338 | -0.4430 | Yes |
| 50 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12998 | -0.364 | -0.4161 | Yes |
| 51 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 13010 | -0.371 | -0.3857 | Yes |
| 52 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13077 | -0.411 | -0.3561 | Yes |
| 53 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 13099 | -0.425 | -0.3219 | Yes |
| 54 | DPP7 | DPP7 Entrez, Source | dipeptidyl-peptidase 7 | 13210 | -0.577 | -0.2815 | Yes |
| 55 | DOK1 | DOK1 Entrez, Source | docking protein 1, 62kDa (downstream of tyrosine kinase 1) | 13216 | -0.591 | -0.2321 | Yes |
| 56 | DDAH2 | DDAH2 Entrez, Source | dimethylarginine dimethylaminohydrolase 2 | 13266 | -0.741 | -0.1734 | Yes |
| 57 | ARMCX2 | ARMCX2 Entrez, Source | armadillo repeat containing, X-linked 2 | 13310 | -1.005 | -0.0919 | Yes |
| 58 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 13324 | -1.119 | 0.0014 | Yes |
