Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | IDX_TSA_UP_CLUSTER6 |
| Enrichment Score (ES) | 0.60546577 |
| Normalized Enrichment Score (NES) | 2.2723553 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 6 | 1.218 | 0.0703 | Yes |
| 2 | GPD1 | GPD1 Entrez, Source | glycerol-3-phosphate dehydrogenase 1 (soluble) | 189 | 0.483 | 0.0847 | Yes |
| 3 | FASN | FASN Entrez, Source | fatty acid synthase | 213 | 0.460 | 0.1097 | Yes |
| 4 | LPL | LPL Entrez, Source | lipoprotein lipase | 230 | 0.451 | 0.1347 | Yes |
| 5 | MGLL | MGLL Entrez, Source | monoglyceride lipase | 241 | 0.443 | 0.1597 | Yes |
| 6 | BCKDHB | BCKDHB Entrez, Source | branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease) | 271 | 0.419 | 0.1819 | Yes |
| 7 | REEP6 | REEP6 Entrez, Source | receptor accessory protein 6 | 274 | 0.418 | 0.2060 | Yes |
| 8 | FAH | FAH Entrez, Source | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 277 | 0.416 | 0.2301 | Yes |
| 9 | CHPT1 | CHPT1 Entrez, Source | choline phosphotransferase 1 | 302 | 0.396 | 0.2513 | Yes |
| 10 | DHCR7 | DHCR7 Entrez, Source | 7-dehydrocholesterol reductase | 333 | 0.375 | 0.2708 | Yes |
| 11 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 356 | 0.360 | 0.2900 | Yes |
| 12 | ETFDH | ETFDH Entrez, Source | electron-transferring-flavoprotein dehydrogenase | 363 | 0.357 | 0.3103 | Yes |
| 13 | GBE1 | GBE1 Entrez, Source | glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV) | 368 | 0.355 | 0.3307 | Yes |
| 14 | ACAA2 | ACAA2 Entrez, Source | acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | 374 | 0.353 | 0.3508 | Yes |
| 15 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 487 | 0.306 | 0.3601 | Yes |
| 16 | CYB5B | CYB5B Entrez, Source | cytochrome b5 type B (outer mitochondrial membrane) | 505 | 0.298 | 0.3762 | Yes |
| 17 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 540 | 0.287 | 0.3902 | Yes |
| 18 | AQP7 | AQP7 Entrez, Source | aquaporin 7 | 573 | 0.276 | 0.4039 | Yes |
| 19 | SCP2 | SCP2 Entrez, Source | sterol carrier protein 2 | 624 | 0.260 | 0.4152 | Yes |
| 20 | SLC25A10 | SLC25A10 Entrez, Source | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 | 642 | 0.255 | 0.4287 | Yes |
| 21 | DBT | DBT Entrez, Source | dihydrolipoamide branched chain transacylase E2 | 799 | 0.220 | 0.4298 | Yes |
| 22 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 839 | 0.215 | 0.4393 | Yes |
| 23 | MCCC1 | MCCC1 Entrez, Source | methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) | 856 | 0.213 | 0.4505 | Yes |
| 24 | PDHB | PDHB Entrez, Source | pyruvate dehydrogenase (lipoamide) beta | 858 | 0.213 | 0.4628 | Yes |
| 25 | CAT | CAT Entrez, Source | catalase | 884 | 0.209 | 0.4730 | Yes |
| 26 | EHD1 | EHD1 Entrez, Source | EH-domain containing 1 | 920 | 0.204 | 0.4822 | Yes |
| 27 | TST | TST Entrez, Source | thiosulfate sulfurtransferase (rhodanese) | 926 | 0.203 | 0.4937 | Yes |
| 28 | SLC25A1 | SLC25A1 Entrez, Source | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 946 | 0.200 | 0.5039 | Yes |
| 29 | RARRES2 | RARRES2 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 2 | 1079 | 0.184 | 0.5046 | Yes |
| 30 | ACAD9 | ACAD9 Entrez, Source | acyl-Coenzyme A dehydrogenase family, member 9 | 1089 | 0.183 | 0.5146 | Yes |
| 31 | HIBADH | HIBADH Entrez, Source | 3-hydroxyisobutyrate dehydrogenase | 1157 | 0.175 | 0.5197 | Yes |
| 32 | HBLD2 | HBLD2 Entrez, Source | HESB like domain containing 2 | 1186 | 0.172 | 0.5275 | Yes |
| 33 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 1296 | 0.164 | 0.5289 | Yes |
| 34 | DECR1 | DECR1 Entrez, Source | 2,4-dienoyl CoA reductase 1, mitochondrial | 1315 | 0.163 | 0.5370 | Yes |
| 35 | PGM1 | PGM1 Entrez, Source | phosphoglucomutase 1 | 1344 | 0.161 | 0.5442 | Yes |
| 36 | ALAD | ALAD Entrez, Source | aminolevulinate, delta-, dehydratase | 1424 | 0.155 | 0.5473 | Yes |
| 37 | LIAS | LIAS Entrez, Source | lipoic acid synthetase | 1435 | 0.155 | 0.5555 | Yes |
| 38 | SFXN1 | SFXN1 Entrez, Source | sideroflexin 1 | 1452 | 0.153 | 0.5632 | Yes |
| 39 | HP | HP Entrez, Source | haptoglobin | 1480 | 0.151 | 0.5699 | Yes |
| 40 | PON2 | PON2 Entrez, Source | paraoxonase 2 | 1531 | 0.147 | 0.5747 | Yes |
| 41 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1535 | 0.147 | 0.5830 | Yes |
| 42 | HADH | HADH Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase | 1615 | 0.142 | 0.5853 | Yes |
| 43 | DLD | DLD Entrez, Source | dihydrolipoamide dehydrogenase | 1628 | 0.141 | 0.5926 | Yes |
| 44 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 1747 | 0.134 | 0.5915 | Yes |
| 45 | DGAT1 | DGAT1 Entrez, Source | diacylglycerol O-acyltransferase homolog 1 (mouse) | 1822 | 0.130 | 0.5934 | Yes |
| 46 | COX7B | COX7B Entrez, Source | cytochrome c oxidase subunit VIIb | 1849 | 0.129 | 0.5990 | Yes |
| 47 | UQCRB | UQCRB Entrez, Source | ubiquinol-cytochrome c reductase binding protein | 1880 | 0.127 | 0.6041 | Yes |
| 48 | ACADL | ACADL Entrez, Source | acyl-Coenzyme A dehydrogenase, long chain | 2024 | 0.121 | 0.6003 | Yes |
| 49 | ISOC1 | ISOC1 Entrez, Source | isochorismatase domain containing 1 | 2061 | 0.119 | 0.6045 | Yes |
| 50 | SCARB1 | SCARB1 Entrez, Source | scavenger receptor class B, member 1 | 2252 | 0.112 | 0.5967 | Yes |
| 51 | HIBCH | HIBCH Entrez, Source | 3-hydroxyisobutyryl-Coenzyme A hydrolase | 2413 | 0.106 | 0.5908 | Yes |
| 52 | DHRS7B | DHRS7B Entrez, Source | dehydrogenase/reductase (SDR family) member 7B | 2433 | 0.105 | 0.5954 | Yes |
| 53 | ATP5O | ATP5O Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) | 2450 | 0.105 | 0.6003 | Yes |
| 54 | MGST1 | MGST1 Entrez, Source | microsomal glutathione S-transferase 1 | 2463 | 0.104 | 0.6055 | Yes |
| 55 | CYB5A | CYB5A Entrez, Source | cytochrome b5 type A (microsomal) | 2608 | 0.099 | 0.6003 | No |
| 56 | SLC25A5 | SLC25A5 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 2756 | 0.094 | 0.5947 | No |
| 57 | SAMM50 | SAMM50 Entrez, Source | sorting and assembly machinery component 50 homolog (S. cerevisiae) | 2829 | 0.090 | 0.5945 | No |
| 58 | SDHA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 2886 | 0.088 | 0.5954 | No |
| 59 | MPDU1 | MPDU1 Entrez, Source | mannose-P-dolichol utilization defect 1 | 3005 | 0.085 | 0.5914 | No |
| 60 | PEX19 | PEX19 Entrez, Source | peroxisomal biogenesis factor 19 | 3069 | 0.083 | 0.5914 | No |
| 61 | SLC2A4 | SLC2A4 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 4 | 3091 | 0.082 | 0.5946 | No |
| 62 | MOSC2 | MOSC2 Entrez, Source | MOCO sulphurase C-terminal domain containing 2 | 3158 | 0.080 | 0.5943 | No |
| 63 | ORM1 | ORM1 Entrez, Source | orosomucoid 1 | 3328 | 0.075 | 0.5859 | No |
| 64 | COX7A2 | COX7A2 Entrez, Source | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | 3647 | 0.068 | 0.5658 | No |
| 65 | SDHC | SDHC Entrez, Source | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 3898 | 0.062 | 0.5505 | No |
| 66 | GSR | GSR Entrez, Source | glutathione reductase | 4018 | 0.059 | 0.5449 | No |
| 67 | UQCRC2 | UQCRC2 Entrez, Source | ubiquinol-cytochrome c reductase core protein II | 4141 | 0.056 | 0.5390 | No |
| 68 | PCAF | PCAF Entrez, Source | p300/CBP-associated factor | 4209 | 0.055 | 0.5371 | No |
| 69 | COX5B | COX5B Entrez, Source | cytochrome c oxidase subunit Vb | 4325 | 0.052 | 0.5314 | No |
| 70 | ABCD2 | ABCD2 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 2 | 4613 | 0.046 | 0.5124 | No |
| 71 | QDPR | QDPR Entrez, Source | quinoid dihydropteridine reductase | 4665 | 0.045 | 0.5112 | No |
| 72 | UQCRC1 | UQCRC1 Entrez, Source | ubiquinol-cytochrome c reductase core protein I | 4861 | 0.041 | 0.4988 | No |
| 73 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 4884 | 0.040 | 0.4995 | No |
| 74 | ATP5D | ATP5D Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit | 5013 | 0.038 | 0.4920 | No |
| 75 | HSD17B12 | HSD17B12 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 12 | 5100 | 0.036 | 0.4876 | No |
| 76 | SUCLG1 | SUCLG1 Entrez, Source | succinate-CoA ligase, GDP-forming, alpha subunit | 5260 | 0.033 | 0.4775 | No |
| 77 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 5395 | 0.030 | 0.4691 | No |
| 78 | PCYOX1 | PCYOX1 Entrez, Source | prenylcysteine oxidase 1 | 5614 | 0.025 | 0.4541 | No |
| 79 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 5670 | 0.024 | 0.4513 | No |
| 80 | TSPAN12 | TSPAN12 Entrez, Source | tetraspanin 12 | 5919 | 0.020 | 0.4337 | No |
| 81 | PLA2G6 | PLA2G6 Entrez, Source | phospholipase A2, group VI (cytosolic, calcium-independent) | 6386 | 0.010 | 0.3991 | No |
| 82 | NDUFA5 | NDUFA5 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa | 6553 | 0.007 | 0.3870 | No |
| 83 | LTC4S | LTC4S Entrez, Source | leukotriene C4 synthase | 6566 | 0.007 | 0.3864 | No |
| 84 | ADIPOQ | ADIPOQ Entrez, Source | adiponectin, C1Q and collagen domain containing | 6570 | 0.007 | 0.3866 | No |
| 85 | NDUFA9 | NDUFA9 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa | 6665 | 0.005 | 0.3798 | No |
| 86 | CAMP | CAMP Entrez, Source | cathelicidin antimicrobial peptide | 6681 | 0.005 | 0.3789 | No |
| 87 | SLC19A1 | SLC19A1 Entrez, Source | solute carrier family 19 (folate transporter), member 1 | 6823 | 0.002 | 0.3684 | No |
| 88 | RETSAT | RETSAT Entrez, Source | retinol saturase (all-trans-retinol 13,14-reductase) | 6880 | 0.001 | 0.3642 | No |
| 89 | CS | CS Entrez, Source | citrate synthase | 7513 | -0.013 | 0.3172 | No |
| 90 | RTN3 | RTN3 Entrez, Source | reticulon 3 | 7533 | -0.013 | 0.3165 | No |
| 91 | TKT | TKT Entrez, Source | transketolase (Wernicke-Korsakoff syndrome) | 7534 | -0.013 | 0.3173 | No |
| 92 | BCAT2 | BCAT2 Entrez, Source | branched chain aminotransferase 2, mitochondrial | 8232 | -0.028 | 0.2662 | No |
| 93 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 8322 | -0.030 | 0.2613 | No |
| 94 | PDAP1 | PDAP1 Entrez, Source | PDGFA associated protein 1 | 8528 | -0.035 | 0.2478 | No |
| 95 | COL15A1 | COL15A1 Entrez, Source | collagen, type XV, alpha 1 | 8592 | -0.037 | 0.2452 | No |
| 96 | ADCY6 | ADCY6 Entrez, Source | adenylate cyclase 6 | 9064 | -0.048 | 0.2124 | No |
| 97 | S100A8 | S100A8 Entrez, Source | S100 calcium binding protein A8 | 10280 | -0.084 | 0.1255 | No |
| 98 | CA2 | CA2 Entrez, Source | carbonic anhydrase II | 10674 | -0.098 | 0.1014 | No |
| 99 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 10723 | -0.099 | 0.1036 | No |
| 100 | RAB3D | RAB3D Entrez, Source | RAB3D, member RAS oncogene family | 10905 | -0.107 | 0.0961 | No |
| 101 | S100A1 | S100A1 Entrez, Source | S100 calcium binding protein A1 | 11272 | -0.125 | 0.0757 | No |
| 102 | CIB2 | CIB2 Entrez, Source | calcium and integrin binding family member 2 | 11337 | -0.128 | 0.0783 | No |
| 103 | DLAT | DLAT Entrez, Source | dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) | 11723 | -0.150 | 0.0580 | No |
| 104 | CBR1 | CBR1 Entrez, Source | carbonyl reductase 1 | 11937 | -0.168 | 0.0517 | No |
| 105 | SDPR | SDPR Entrez, Source | serum deprivation response (phosphatidylserine binding protein) | 12367 | -0.211 | 0.0315 | No |
| 106 | UNC119 | UNC119 Entrez, Source | unc-119 homolog (C. elegans) | 12456 | -0.221 | 0.0377 | No |
| 107 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 12519 | -0.231 | 0.0465 | No |
| 108 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 12719 | -0.269 | 0.0471 | No |
