Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | IGF_VS_PDGF_DN |
| Enrichment Score (ES) | -0.5897984 |
| Normalized Enrichment Score (NES) | -1.6179386 |
| Nominal p-value | 0.028846154 |
| FDR q-value | 0.1095136 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 140 | 0.550 | 0.0890 | No |
| 2 | DSCR1L1 | DSCR1L1 Entrez, Source | Down syndrome critical region gene 1-like 1 | 1229 | 0.168 | 0.0377 | No |
| 3 | ERRFI1 | ERRFI1 Entrez, Source | ERBB receptor feedback inhibitor 1 | 1295 | 0.164 | 0.0625 | No |
| 4 | ATP1A3 | ATP1A3 Entrez, Source | ATPase, Na+/K+ transporting, alpha 3 polypeptide | 1543 | 0.146 | 0.0704 | No |
| 5 | DUSP4 | DUSP4 Entrez, Source | dual specificity phosphatase 4 | 1582 | 0.144 | 0.0936 | No |
| 6 | GREM1 | GREM1 Entrez, Source | gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis) | 3058 | 0.083 | -0.0021 | No |
| 7 | PRKG2 | PRKG2 Entrez, Source | protein kinase, cGMP-dependent, type II | 4208 | 0.055 | -0.0784 | No |
| 8 | CRYL1 | CRYL1 Entrez, Source | crystallin, lambda 1 | 5904 | 0.020 | -0.2020 | No |
| 9 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 6077 | 0.017 | -0.2119 | No |
| 10 | PTGS1 | PTGS1 Entrez, Source | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | 6103 | 0.016 | -0.2109 | No |
| 11 | FBXO32 | FBXO32 Entrez, Source | F-box protein 32 | 8720 | -0.039 | -0.4002 | No |
| 12 | PHEX | PHEX Entrez, Source | phosphate regulating endopeptidase homolog, X-linked (hypophosphatemia, vitamin D resistant rickets) | 8980 | -0.045 | -0.4115 | No |
| 13 | SPAG5 | SPAG5 Entrez, Source | sperm associated antigen 5 | 9056 | -0.048 | -0.4085 | No |
| 14 | STOM | STOM Entrez, Source | stomatin | 9313 | -0.055 | -0.4178 | No |
| 15 | MGP | MGP Entrez, Source | matrix Gla protein | 9643 | -0.064 | -0.4310 | No |
| 16 | CDKN2D | CDKN2D Entrez, Source | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 9788 | -0.068 | -0.4296 | No |
| 17 | CD53 | CD53 Entrez, Source | CD53 molecule | 10105 | -0.078 | -0.4391 | No |
| 18 | CAV2 | CAV2 Entrez, Source | caveolin 2 | 12113 | -0.183 | -0.5568 | Yes |
| 19 | THBD | THBD Entrez, Source | thrombomodulin | 12150 | -0.186 | -0.5258 | Yes |
| 20 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 12692 | -0.262 | -0.5190 | Yes |
| 21 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 12840 | -0.300 | -0.4758 | Yes |
| 22 | CAPG | CAPG Entrez, Source | capping protein (actin filament), gelsolin-like | 13018 | -0.375 | -0.4212 | Yes |
| 23 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 13213 | -0.582 | -0.3306 | Yes |
| 24 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 13270 | -0.762 | -0.1970 | Yes |
| 25 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 13324 | -1.119 | 0.0014 | Yes |
