Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | INTERPHASE_OF_MITOTIC_CELL_CYCLE |
| Enrichment Score (ES) | -0.5638474 |
| Normalized Enrichment Score (NES) | -1.6494496 |
| Nominal p-value | 0.00984252 |
| FDR q-value | 0.09736999 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SPDYA | SPDYA Entrez, Source | speedy homolog A (Drosophila) | 1994 | 0.122 | -0.1198 | No |
| 2 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 2067 | 0.119 | -0.0959 | No |
| 3 | TBRG4 | TBRG4 Entrez, Source | transforming growth factor beta regulator 4 | 3101 | 0.081 | -0.1534 | No |
| 4 | USH1C | USH1C Entrez, Source | Usher syndrome 1C (autosomal recessive, severe) | 3303 | 0.076 | -0.1498 | No |
| 5 | KPNA2 | KPNA2 Entrez, Source | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 3717 | 0.066 | -0.1645 | No |
| 6 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 3808 | 0.064 | -0.1556 | No |
| 7 | GFI1 | GFI1 Entrez, Source | growth factor independent 1 | 5640 | 0.025 | -0.2870 | No |
| 8 | INHBA | INHBA Entrez, Source | inhibin, beta A (activin A, activin AB alpha polypeptide) | 7375 | -0.010 | -0.4149 | No |
| 9 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 7589 | -0.014 | -0.4273 | No |
| 10 | KATNA1 | KATNA1 Entrez, Source | katanin p60 (ATPase-containing) subunit A 1 | 7746 | -0.018 | -0.4347 | No |
| 11 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 8322 | -0.030 | -0.4704 | No |
| 12 | MAP3K11 | MAP3K11 Entrez, Source | mitogen-activated protein kinase kinase kinase 11 | 8842 | -0.042 | -0.4991 | No |
| 13 | PPP6C | PPP6C Entrez, Source | protein phosphatase 6, catalytic subunit | 8915 | -0.044 | -0.4937 | No |
| 14 | CUL5 | CUL5 Entrez, Source | cullin 5 | 9220 | -0.052 | -0.5037 | No |
| 15 | CDKN3 | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 9252 | -0.053 | -0.4930 | No |
| 16 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 9560 | -0.061 | -0.5010 | No |
| 17 | CDKN2D | CDKN2D Entrez, Source | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 9788 | -0.068 | -0.5014 | No |
| 18 | ANAPC4 | ANAPC4 Entrez, Source | anaphase promoting complex subunit 4 | 9814 | -0.069 | -0.4863 | No |
| 19 | APBB1 | APBB1 Entrez, Source | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 10220 | -0.082 | -0.4965 | No |
| 20 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 11117 | -0.118 | -0.5348 | Yes |
| 21 | CDK10 | CDK10 Entrez, Source | cyclin-dependent kinase (CDC2-like) 10 | 11493 | -0.137 | -0.5292 | Yes |
| 22 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 11672 | -0.148 | -0.5060 | Yes |
| 23 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 11673 | -0.148 | -0.4695 | Yes |
| 24 | ACVR1 | ACVR1 Entrez, Source | activin A receptor, type I | 11998 | -0.173 | -0.4513 | Yes |
| 25 | KHDRBS1 | KHDRBS1 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 1 | 12056 | -0.178 | -0.4117 | Yes |
| 26 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 12163 | -0.188 | -0.3734 | Yes |
| 27 | CDC23 | CDC23 Entrez, Source | CDC23 (cell division cycle 23, yeast, homolog) | 12182 | -0.190 | -0.3280 | Yes |
| 28 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 12251 | -0.199 | -0.2841 | Yes |
| 29 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 12725 | -0.270 | -0.2531 | Yes |
| 30 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 12794 | -0.284 | -0.1881 | Yes |
| 31 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 13099 | -0.425 | -0.1062 | Yes |
| 32 | BCAT1 | BCAT1 Entrez, Source | branched chain aminotransferase 1, cytosolic | 13167 | -0.505 | 0.0131 | Yes |
