Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | IRITANI_ADPROX_DN |
| Enrichment Score (ES) | -0.63415927 |
| Normalized Enrichment Score (NES) | -1.9142029 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.021166768 |
| FWER p-Value | 0.401 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RGS4 | RGS4 Entrez, Source | regulator of G-protein signalling 4 | 1058 | 0.187 | -0.0562 | No |
| 2 | SELP | SELP Entrez, Source | selectin P (granule membrane protein 140kDa, antigen CD62) | 1408 | 0.156 | -0.0629 | No |
| 3 | BMP6 | BMP6 Entrez, Source | bone morphogenetic protein 6 | 1653 | 0.140 | -0.0638 | No |
| 4 | PROCR | PROCR Entrez, Source | protein C receptor, endothelial (EPCR) | 1750 | 0.134 | -0.0542 | No |
| 5 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 1938 | 0.125 | -0.0527 | No |
| 6 | CDH2 | CDH2 Entrez, Source | cadherin 2, type 1, N-cadherin (neuronal) | 2409 | 0.106 | -0.0748 | No |
| 7 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 2530 | 0.102 | -0.0711 | No |
| 8 | NRCAM | NRCAM Entrez, Source | neuronal cell adhesion molecule | 3263 | 0.077 | -0.1165 | No |
| 9 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 3320 | 0.076 | -0.1113 | No |
| 10 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 4003 | 0.059 | -0.1551 | No |
| 11 | CAP2 | CAP2 Entrez, Source | CAP, adenylate cyclase-associated protein, 2 (yeast) | 4433 | 0.050 | -0.1811 | No |
| 12 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 4898 | 0.040 | -0.2110 | No |
| 13 | MAPKAPK3 | MAPKAPK3 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 3 | 5140 | 0.035 | -0.2248 | No |
| 14 | LPXN | LPXN Entrez, Source | leupaxin | 5312 | 0.032 | -0.2336 | No |
| 15 | LYL1 | LYL1 Entrez, Source | lymphoblastic leukemia derived sequence 1 | 5624 | 0.025 | -0.2539 | No |
| 16 | LTBP2 | LTBP2 Entrez, Source | latent transforming growth factor beta binding protein 2 | 7613 | -0.015 | -0.4015 | No |
| 17 | ICAM2 | ICAM2 Entrez, Source | intercellular adhesion molecule 2 | 7636 | -0.015 | -0.4012 | No |
| 18 | SLC38A6 | SLC38A6 Entrez, Source | solute carrier family 38, member 6 | 7813 | -0.019 | -0.4121 | No |
| 19 | TFEC | TFEC Entrez, Source | transcription factor EC | 8147 | -0.026 | -0.4338 | No |
| 20 | FAP | FAP Entrez, Source | fibroblast activation protein, alpha | 8649 | -0.038 | -0.4668 | No |
| 21 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 10723 | -0.099 | -0.6102 | No |
| 22 | EMP3 | EMP3 Entrez, Source | epithelial membrane protein 3 | 10906 | -0.107 | -0.6105 | No |
| 23 | PDLIM4 | PDLIM4 Entrez, Source | PDZ and LIM domain 4 | 11133 | -0.119 | -0.6127 | No |
| 24 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 11420 | -0.132 | -0.6176 | Yes |
| 25 | SRPX | SRPX Entrez, Source | sushi-repeat-containing protein, X-linked | 11499 | -0.137 | -0.6063 | Yes |
| 26 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 11683 | -0.149 | -0.6015 | Yes |
| 27 | TCN2 | TCN2 Entrez, Source | transcobalamin II; macrocytic anemia | 11922 | -0.167 | -0.5985 | Yes |
| 28 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 12177 | -0.189 | -0.5940 | Yes |
| 29 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 12248 | -0.199 | -0.5744 | Yes |
| 30 | ARL6IP5 | ARL6IP5 Entrez, Source | ADP-ribosylation-like factor 6 interacting protein 5 | 12296 | -0.204 | -0.5524 | Yes |
| 31 | PRNP | PRNP Entrez, Source | prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) | 12376 | -0.212 | -0.5318 | Yes |
| 32 | NRP1 | NRP1 Entrez, Source | neuropilin 1 | 12499 | -0.229 | -0.5124 | Yes |
| 33 | PLAU | PLAU Entrez, Source | plasminogen activator, urokinase | 12662 | -0.256 | -0.4925 | Yes |
| 34 | MLLT11 | MLLT11 Entrez, Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 12710 | -0.266 | -0.4628 | Yes |
| 35 | PLA2G4A | PLA2G4A Entrez, Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 12946 | -0.338 | -0.4383 | Yes |
| 36 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12998 | -0.364 | -0.3966 | Yes |
| 37 | PFKM | PFKM Entrez, Source | phosphofructokinase, muscle | 13007 | -0.369 | -0.3510 | Yes |
| 38 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 13197 | -0.560 | -0.2953 | Yes |
| 39 | AXL | AXL Entrez, Source | AXL receptor tyrosine kinase | 13219 | -0.601 | -0.2217 | Yes |
| 40 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 13233 | -0.633 | -0.1436 | Yes |
| 41 | GBP2 | GBP2 Entrez, Source | guanylate binding protein 2, interferon-inducible | 13329 | -1.214 | 0.0010 | Yes |
